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Ileal Perforation with Norovirus Gastroenteritis in a 3-Month-Old Infant

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주제분류소아과학

초록

Noroviruses have been recognized as the leading cause of epidemic and sporadic gastroenteritis since the advent of molecular diagnostic technique. They have been documented in 5-31% of pediatric patients hospitalized with gastroenteritis. Although norovirus gastroenteritis is typically mild and self-limited, it causes severe, but sometimes fatal, conditions in the vulnerable population such as immunocompromised patients, young children, and the elderly. Bowel perforation due to norovirus infection is rare. We report a case of small bowel perforation with norovirus gastroenteritis in the infant with Down syndrome during the hospitalization with pneumonia. Severe dehydration may cause bowel ischemia and could have triggered bowel perforation in this case. Physicians should be alert to the potential surgical complications followed by severe acute diarrhea, especially in high risk groups.

Abstract

Noroviruses have been recognized as the leading cause of epidemic and sporadic gastroenteritis since the advent of molecular diagnostic technique. They have been documented in 5-31% of pediatric patients hospitalized with gastroenteritis. Although norovirus gastroenteritis is typically mild and self-limited, it causes severe, but sometimes fatal, conditions in the vulnerable population such as immunocompromised patients, young children, and the elderly. Bowel perforation due to norovirus infection is rare. We report a case of small bowel perforation with norovirus gastroenteritis in the infant with Down syndrome during the hospitalization with pneumonia. Severe dehydration may cause bowel ischemia and could have triggered bowel perforation in this case. Physicians should be alert to the potential surgical complications followed by severe acute diarrhea, especially in high risk groups.

참고문헌 (18)

  1. Glass RI, "Norovirus gastroenteritis", N Engl J Med, 361, pp.1776~1785 (2009)
  2. Matthews JE, "The epidemiology of published norovirus outbreaks: a review of risk factors associated with attack rate and genogroup", Epidemiol Infect, 140, pp.1161~1172 (2012)
  3. Mattner F, "Risk groups for clinical complications of norovirus infections: an outbreak investigation", Clin Microbiol Infect, 12, pp.69~74 (2006)
  4. Patel MM, "Systematic literature review of role of noroviruses in sporadic gastroenteritis", Emerg Infect Dis, 14, pp.1224~1231 (2008)
  5. Bull RA, "Emergence of a new norovirus genotype II.4 variant associated with global outbreaks of gastroenteritis", J Clin Microbiol, 44, pp.327~333 (2006)
  6. Mans J, "Emerging norovirus GII.4 2008 variant detected in hospitalised paediatric patients in South Africa", J Clin Virol, 49, pp.258~264 (2010)
  7. Johnston CP, "Outbreak management and implications of a nosocomial norovirus outbreak", Clin Infect Dis, 45, pp.534~540 (2007)
  8. Beersma MF, "Norovirus in a Dutch tertiary care hospital (2002-2007): frequent nosocomial transmission and dominance of GIIb strains in young children", J Hosp Infect, 71, pp.199~205 (2009)
  9. Beersma MF, "Unrecognized norovirus infections in health care institutions and their clinical impact", J Clin Microbiol, 50, pp.3040~3045 (2012)
  10. Pawa N, "Spontaneous bowel perforation due to norovirus: a case report", Cases J, 2, pp.9101~ (2009)
  11. Souza M, "Pathogenesis and immune responses in gnotobiotic calves after infection with the genogroup II.4-HS66strain of human norovirus", J Virol, 82, pp.1777~1786 (2008)
  12. Pelizzo G, "Isolated colon ischemia with norovirus infection in preterm babies: a case series", J Med Case Rep, 7, pp.108~ (2013)
  13. Turcios-Ruiz RM, "Outbreak of necrotizing enterocolitis caused by norovirus in a neonatal intensive care unit", J Pediatr, 153, pp.339~344 (2008)
  14. Ueda N, "Duodenal perforation associated with norovirus and rotavirus gastroenteritis", Clin Case Rep, 1, pp.47~49 (2013)
  15. Chen JC, "Spontaneous bowel perforation in infants and young children: a clinicopathologic analysis of pathogenesis", J Pediatr Gastroenterol Nutr, 30, pp.432~435 (2000)
  16. Ballance WA, "Pathology of neonatal necrotizing enterocolitis: a ten-year experience", J Pediatr, 117, pp.S6~S13 (1990)
  17. Kusters MA, "Intrinsic defect of the immune system in children with Down syndrome: a review", Clin Exp Immunol, 156, pp.189~193 (2009)
  18. Verstegen RH, "Down syndrome B-lymphocyte subpopulations, intrinsic defect or decreased T-lymphocyte help", Pediatr Res, 67, pp.563~569 (2010)

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