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Community Management of Acute Malnutrition in the Developing World

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주제분류소아과학

초록

Globally, acute malnutrition triggers more than 50% of childhood mortality in children under 5 years old, which implies that about 3.5 million children die of malnutrition each year. Prior to the advent of ready-to-use therapeutic food (RUTF), the management of acute malnutrition was limited to hospitals, resulting in low coverage rates with high mortality, as malnourished cases were indentified at later stages often plagued with complications. However, current availability of RUTF has enabled malnourished children to be treated at communities. Further, because RUTF is dehydrated and sealed, it has the added advantage of a lower risk of bacterial contamination, thereby prolonging its storage life at room temperature. Recent data indicate that Community Management of Acute Malnutrition (CMAM) is as cost effective as other high-impact public health measures such as oral rehydration therapy for acute diarrheal diseases, vitamin A supplementation, and antibiotic treatment for acute respiratory infections. Despite the high efficacy of CMAM programs, CMAM still draws insufficient attention for global implementation, suggesting that CMAM programs should be integrated into local or regional routine health systems. Knowledge gaps requiring further research include: the definition of practical screening criteria for malnourished children at communities, the need for systematic antibiotic therapy during malnutrition treatment, and the dietary management of severe malnutrition in children below 6 months of age.

Abstract

Globally, acute malnutrition triggers more than 50% of childhood mortality in children under 5 years old, which implies that about 3.5 million children die of malnutrition each year. Prior to the advent of ready-to-use therapeutic food (RUTF), the management of acute malnutrition was limited to hospitals, resulting in low coverage rates with high mortality, as malnourished cases were indentified at later stages often plagued with complications. However, current availability of RUTF has enabled malnourished children to be treated at communities. Further, because RUTF is dehydrated and sealed, it has the added advantage of a lower risk of bacterial contamination, thereby prolonging its storage life at room temperature. Recent data indicate that Community Management of Acute Malnutrition (CMAM) is as cost effective as other high-impact public health measures such as oral rehydration therapy for acute diarrheal diseases, vitamin A supplementation, and antibiotic treatment for acute respiratory infections. Despite the high efficacy of CMAM programs, CMAM still draws insufficient attention for global implementation, suggesting that CMAM programs should be integrated into local or regional routine health systems. Knowledge gaps requiring further research include: the definition of practical screening criteria for malnourished children at communities, the need for systematic antibiotic therapy during malnutrition treatment, and the dietary management of severe malnutrition in children below 6 months of age.

참고문헌 (62)

  1. "The World Bank Joint Child Malnutrition, Levels & Trends in Child Malnutrition" (2012)[URL]
  2. Caulfield LE, "Undernutrition as an underlying cause of child deaths associated with diarrhea, pneumonia, malaria, and measles", Am J Clin Nutr, 80, pp.193~198 (2004)
  3. Collins S, "Key issues in the success of community-based management of severe malnutrition", Food Nutr Bull, 27(3), pp.49~82 (2006)
  4. Black RE, "Maternal and child undernutrition: global and regional exposures and health consequences", Lancet, 371, pp.243~260 (2008)
  5. At least one-third of poor countries’ disease burden is due to malnutrition, "Mason JB", Fogarty International Center of the National Institutes of Health., ~, pp.Disease Control Priorities Project (DCPP) Working Paper No. 1 (2003)
  6. Bryce J, "Maternal and child undernutrition: effective action at national level", Lancet, 371, pp.510~526 (2008)
  7. Nassar MF, "T-lymphocyte subsets and thymic size in malnourished infants in Egypt: a hospital-based study", East Mediterr Health J, 13, pp.1031~1042 (2007)
  8. Salimonu LS, "Lymphocyte subpopulations and antibody levels in immunized malnourished children", Br J Nutr, 48, pp.7~14 (1982)
  9. Savy M, "Landscape analysis of interactions between nutrition and vaccine responses in children", J Nutr, 139, pp.2154~2218 (2009)
  10. Hafez M, "Antibody production and complement system in protein energy malnutrition", J Trop Med Hyg, 80, pp.36~39 (1977)
  11. Vesikari T, "Efficacy of a pentavalent rotavirus vaccine in reducing rotavirus-associated health care utilization across three regions (11 countries)", Int J Infect Dis, 11(2), pp.29~35 (2007)
  12. Greenwood BM, "The immune response to vaccination in undernourished and well-nourished Nigerian children", Ann Trop Med Parasitol, 80, pp.537~544 (1986)
  13. Chopra K, "Antibody response of infants in tropics to five doses of oral polio vaccine", J Trop Pediatr, 35, pp.19~23 (1989)
  14. Chandra RK, "Reduced secretory antibody response to live attenuated measles and poliovirus vaccines in malnourished children", Br Med J, 2, pp.583~585 (1975)
  15. Vesikari T, "Rotavirus Efficacy and Safety Trial (REST) Study Team. Safety and efficacy of a pentavalent human-bovine (WC3) reassortant rotavirus vaccine", N Engl J Med, 354, pp.23~33 (2006)
  16. Ciarlet M, "Development of a rotavirus vaccine: clinical safety, immunogenicity, and efficacy of the pentavalent rotavirus vaccine, RotaTeq", Vaccine, 27(6), pp.72~81 (2009)
  17. Block SL, "Efficacy, immunogenicity, and safety of a pentavalent human-bovine (WC3) reassortant rotavirus vaccine at the end of shelf life", Pediatrics, 119, pp.11~18 (2007)
  18. "Child Growth Standards and the Identification of Severe Acute Malnutrition in Infants and Children. A Joint Statement by the World Health Organization and the United Nations Children’s Fund, 2009" (2009)[URL]
  19. Mason JB, "Treatment of severe malnutrition in relief", Lancet, 1, pp.332~335 (1974)
  20. "Management of severe malnutrition: a manual for physicians and other senior health workers" (1999)[URL]
  21. "Malnutrition and infection. A review. 1989. Geneva, WHO. Advisor committee on coordination/Subcommittee on nutrition" (1989)[URL]
  22. Cunningham-Rundles S, "Effects of nutritional status on immunological function", Am J Clin Nutr, 35(5), pp.1202~1210 (1982)
  23. Golden MH, "Treatment of malnutrition in refugee camps", Lancet, 342, pp.360~ (1993)
  24. "The management of nutrition in major emergencies" (2000)[URL]
  25. Boelaert M, "Nutrition guidelines. 1st" (1995), Medecins sans Frontieres
  26. "IMCI: the integrated approach" (1997)[URL]
  27. Ahmed T, "Mortality in severely malnourished children with diarrhoea and use of a standardised management protocol", Lancet, 353, pp.1919~1922 (1999)
  28. Deen JL, "Implementation of WHO guidelines on management of severe malnutrition in hospitals in Africa", Bull World Health Organ, 81, pp.237~243 (2003)
  29. Prudhon C, "Comparison of weight- and height-based indices for assessing the risk of death in severely malnourished children", Am J Epidemiol, 144, pp.116~123 (1996)
  30. "WHO global health atlas-human resources for health"[URL]
  31. Cook R, "Is hospital the place for the treatment of malnourished children?", J Trop Pediatr Environ Child Health, 17, pp.15~25 (1971)
  32. Bengoa JM, "Nutrition rehabilitation centres", J Trop Pediatr, 13, pp.169~176 (1967)
  33. Ashworth A, "Efficacy and effectiveness of community-based treatment of severe malnutrition", Food Nutr Bull, 27(3), pp.24~48 (2006)
  34. "Treatment of severe malnutrition with a therapeutic spread. ENN Field Exchange" (1997)[URL]
  35. Briend A, "Treatment of severe child malnutrition in refugee camps", Eur J Clin Nutr, 47, pp.750~754 (1993)
  36. Briend A, "Ready-to-use therapeutic food for treatment of marasmus", Lancet, 353, pp.1767~1768 (1999)
  37. Diop el HI, "Comparison of the efficacy of a solid ready-to-use food and a liquid, milk-based diet for the rehabilitation of severely malnourished children: a randomized trial", Am J Clin Nutr, 78, pp.302~307 (2003)
  38. Navarro-Colorado C, "Clinical trial of BP100 vs F100 milk for rehabilitation of severe malnutrition", ENN Field Exchange, 24, pp.22~24 (2005)
  39. "Community-based Therapeutic Care (CTC). Emergency Nutrition Network (ENN) Special Supplement Series No. 2" (2004)[URL]
  40. Myatt M, "A review of methods to detect cases of severely malnourished children in the community for their admission into community-based therapeutic care programs", Food Nutr Bull, 27(3), pp.7~23 (2006)
  41. Pelletier DL, "The relationship between child anthropometry and mortality in developing countries: implications for policy, programs and future research", J Nutr, 124(10), pp.2047~2081 (1994)
  42. Briend A, "Usefulness of nutritional indices and classifications in predicting death of malnourished children", Br Med J (Clin Res Ed), 293, pp.373~375 (1986)
  43. Lapidus N, "Prognostic accuracy of WHO growth standards to predict mortality in a large-scale nutritional program in Niger", PLoS Med, 6, pp.39~ (2009)
  44. English M, "Assessment of inpatient paediatric care in first referral level hospitals in 13 districts in Kenya", Lancet, 363, pp.1948~1953 (2004)
  45. Berkley J, "Assessment of severe malnutrition among hospitalized children in rural Kenya: comparison of weight for height and mid upper arm circumference", JAMA, 294, pp.591~597 (2005)
  46. "Valid International, Community Based Therapeutic Care, first edition 2006" (2006)[URL]
  47. Schofield C, "A. Why have mortality rates for severe malnutrition remained so high?", Bull World Health Organ, 74, pp.223~229 (1996)
  48. Golden M, "The effects of malnutrition in the metabolism of children", Trans R Soc Trop Med Hyg, 82, pp.3~6 (1988)
  49. Golden MHN, "Severe Malnutrition. The Oxford Textbook of Medicine", pp.1278~1296 (1996), Oxford University Press
  50. Collins S, "Outpatient care for severely malnourished children in emergency relief programmes: a retrospective cohort study", Lancet, 360, pp.1824~1830 (2002)
  51. "The Sphere Project: Humanitarian charter and minimum standards in disaster response" (2011)[URL]
  52. Tectonidis M, "Crisis in Niger--outpatient care for severe acute malnutrition", N Engl J Med, 354, pp.224~227 (2006)
  53. Collins S, "Management of severe acute malnutrition in children", Lancet, 368, pp.1992~2000 (2006)
  54. Vygen SB, "Treatment of severe acute malnutrition in infants aged <6 months in niger", J Pediatr (2012)
  55. Report of an informal consultation on the community-based management of severe malnutrition in children, "WHO", ~ (2012)
  56. Van Damme W, "Medical assistance to self-settled refugees. Guinea 1990–1996" (1998), ITG Press
  57. Jha P, "The cost-effectiveness of forty health interventions in Guinea", Health Policy Plan, 13, pp.249~262 (1998)
  58. Sandige H, "Home-based treatment of malnourished Malawian children with locally produced or imported ready-to-use food", J Pediatr Gastroenterol Nutr, 39, pp.141~146 (2004)
  59. Manary MJ, "Home based therapy for severe malnutrition with ready-to-use food", Arch Dis Child, 89, pp.557~561 (2004)
  60. Ndekha MJ, "Home-based therapy with ready-to-use therapeutic food is of benefit to malnourished, HIV-infected Malawian children", Acta Paediatr, 94, pp.222~225 (2005)
  61. Ashraf H, "A follow-up experience of 6 months after treatment of children with severe acute malnutrition in Dhaka, Bangladesh", J Trop Pediatr, 58, pp.253~257 (2012)
  62. Puett C, "Cost-effectiveness of the community-based management of severe acute malnutrition by community health workers in southern Bangladesh", Health Policy Plan (2012)

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