Comparison of the immunogenicity between bacterial ghost and formalin-killed bacteria for Vibrio vulnificus
0
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Vibrio vulnificus ghosts (VVG) were generated using a mobilizable vector including a thermosensitive expression cassette by conjugation. The vaccine potential of VVG was investigated in mouse. Mice immunized with VVG showed significantly higher antibody titer than those with formalin-killed V. vulnificus. The present study supports the conceptive usefulness of bacterial ghosts as vaccine candidates.
Abstract
Vibrio vulnificus ghosts (VVG) were generated using a mobilizable vector including a thermosensitive expression cassette by conjugation. The vaccine potential of VVG was investigated in mouse. Mice immunized with VVG showed significantly higher antibody titer than those with formalin-killed V. vulnificus. The present study supports the conceptive usefulness of bacterial ghosts as vaccine candidates.
참고문헌 (24)
- Bowdre, J.H., "Edema and hemoconcenration in mice experimentally infected with Vibrio vulnificus", Infect. Immun, 32, pp.1193~1199 (1981)
- Chuang, Y.C., "Vibrio vulnificus infection in Taiwan: Report of 28 cases and review of clinical manifestations and treatment", Clin. Infect. Dis, 15, pp.1~6 (1992)
- Ferguson, M., "Antigenic structure of poliovirus in inactivated vaccines", J. Gen. Virol, 74, pp.685~690 (1993)
- Hamashima, H., "A simple and rapid method for transformation of Vibrio species by electroporation", Methods Mol. Biol, 47, pp.155~160 (1995)
- Hansen, J., "Liposome delivery of Chlamydia muridarum major outer membrane protein primes a Th1 response that protects against genital chlamydial infection in a mouse model", J infect. Dis, 198, pp.758~767 (2008)
- Heckels, J.E., "The potential protective effect of immunization with outer membrane protein I from Neisseria gonorhoeae", J. Gen. Microbiol, 135, pp.2269~2276 (1989)
- Hlady, W.G., "Vibrio vulnificus infections associated with raw oyster consumption Florida, 1981-1992", Arch. Dermatol, 129, pp.957~958 (1993)
- Huter, V., "Improved protection against lung colonization by Actinobacillus pleuropneumoniae ghosts: characterization of a genetically inactivated vaccine", J. Biotechnol, 83, pp.161~172 (2000)
- Cho-Rok Jung, "Immunization with Major Outer Membrane Protein of Vibrio vulnificus Elicits Protective Antibodies in a Murine Model", The Journal of Microbiology, 43(5), pp.437~442 (2005), 한국미생물학회
- Kasten, R.W., "Pateurella multocida produces a protein with homology to the P6 outer membrane protein of Haemophilus influenzae", Infect. Immunol, 63, pp.989~993 (1995)
- Kawai, K., "Conserved 37 kDa outer membrane protein of Edwardsiella tarda is an effective vaccine candidate", Vaccine, 22, pp.3411~3418 (2004)
- Kelly, M.T., "Effect of temperature and salinity on Vibrio (beneckea) vulnificus occurrence in a Gulf coast environment", App. Environ. Microbiol, 44, pp.820~824 (1982)
- Kwon, S.R., "Generation of Vibrio anguillarum ghost by coexpression of PhiX174 lysis E gene and Staphylococcal Nuclease A gene", Mol. Biotechnol, 42, pp.154~159 (2009)
- Kwon, S. R., "Efficacy of oral immunization with Edwardsiella tarda ghosts against edwardsiellosis in olive flounder (Paralichthys olivaceus)", AQUACULTURE, 269, pp.84~88 (2007), ELSEVIER SCIENCE BV
- Kwon, S. R., "Generation of Edwardsiella tarda ghosts by bacteriophage PhiX174 lysis gene E", AQUACULTURE, 250, pp.16~21 (2005), ELSEVIER SCIENCE BV
- Kwon, S. R., "Protection of tilapia (Oreochromis mosambicus) from edwardsiellosis by vaccination with Edwardsiella tarda ghosts", FISH SHELLFISH IMMUNOLOGY, 20(4), pp.621~626 (2006), ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD
- Lutwyche, P., "A conserved Aeromonas salmonicida porin provides protective immunity to rainbow trout", Infect. Immunol, 63, pp.3137~3142 (1995)
- Melamed, D., "A vaccine against avian colibacillosis based on ultrasonic inactivation of Escherichia coli", Avian Dis, 35, pp.17~22 (1991)
- Nencioni, L., "Properties of pertussis toxin mutant PT-9K", 129G after formaldehyde treatment, 1991, pp.59, 625~630
- Park, S.D., "Vibrio vulnificus septicemia in Korea: clinical and epidemiologic findings in seventy patients", J. Am. Acad. Dermatol, 24, pp.397~403 (1991)
- Sengupta, D.K., "Major outer membrane proteins of Vibrio cholerae and their role in induction of protective immunity through inhibition of intestinal colonization", Infect. Immunol, 60, pp.4848~4855 (1992)
- Tamplin, M, "Isolation and characterization of Vibrio vulnificus from two Florida estuaries", App. Environ. Microbiol, 44, pp.1466~1470 (1982)
- Tison, D.L., "Vibrio vulnificus biogroup 2: new biogroup pathogenic for eels", Appl. Environ. Microbiol, 44, pp.640~646 (1982)
- Tu, F.P., "Effect of oral immunization with Aeromonas hydrophila ghosts on protection against experimental fish infection", Lett. Appl. Microbiol, 50, pp.13~17 (2010)
