조현병에서 긍정 정서가 인지적 갈등 해결에 미치는 영향과 사회적 무쾌감증과의 관계
Deficit of Executive Control of Positive Emotional Information and Its Association with Social Anhedonia in Schizophrenia
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Objectives : Schizophrenia has been considered to be characterized by an abnormality in attention, especially in the executive control. Emotion is an important component of the executive control. The aim of this study was to investigate the influence of emotion on the executive control in patients with schizophrenia. Methods : Participants were 20 healthy controls and 19 subjects with schizophrenia. They viewed full-color pictures selected from the International Affective Picture System. During each trial, an emotional picture, which was either positive or negative, lit up on either the left or right side. Participants were instructed to respond to the emotional valance of each stimulus by pressing a button with their left or right index finger, while ignoring its presented side. Results : There was a group difference in the response time, and patients with schizophrenia exhibited an impairment in the executive control of emotional information. However, there was no difference in the response time between the emotional conditions. In the patient group, the missing rate in the positive emotional condition was correlated with the severity of social anhedonia, whereas the missing rate in the negative emotional condition was correlated with the severity of positive symptoms. Conclusion : Patients with schizophrenia have a deficit in the executive control of positive emotional information as well as negative emotion, but it may be due to different underlying mechanisms.
Abstract
Objectives : Schizophrenia has been considered to be characterized by an abnormality in attention, especially in the executive control. Emotion is an important component of the executive control. The aim of this study was to investigate the influence of emotion on the executive control in patients with schizophrenia. Methods : Participants were 20 healthy controls and 19 subjects with schizophrenia. They viewed full-color pictures selected from the International Affective Picture System. During each trial, an emotional picture, which was either positive or negative, lit up on either the left or right side. Participants were instructed to respond to the emotional valance of each stimulus by pressing a button with their left or right index finger, while ignoring its presented side. Results : There was a group difference in the response time, and patients with schizophrenia exhibited an impairment in the executive control of emotional information. However, there was no difference in the response time between the emotional conditions. In the patient group, the missing rate in the positive emotional condition was correlated with the severity of social anhedonia, whereas the missing rate in the negative emotional condition was correlated with the severity of positive symptoms. Conclusion : Patients with schizophrenia have a deficit in the executive control of positive emotional information as well as negative emotion, but it may be due to different underlying mechanisms.
참고문헌 (32)
- Heinrichs RW, "Neurocognitive deficit in schizophrenia: a quantitative review of the evidence", Neuropsychology, 12, pp.426~445 (1998)
- Milev P, "Predictive values of neurocognition and negative symptoms on functional outcome in schizophrenia: a longitudinal first-episode study with 7-year follow-up", Am J Psychiatry, 162, pp.495~506 (2005)
- Green MF, "What are the functional consequences of neurocognitive deficits in schizophrenia?", Am J Psychiatry, 153, pp.321~330 (1996)
- Benedict RHB, "Effects of attention training on information processing in schizophrenia", Schizophr Bull, 20, pp.537~546 (1994)
- McGurk S, "A meta-analysis of cognitive remediation in schizophrenia", Am J Psychiatry, 164, pp.1791~1802 (2007)
- Dickinson D, "A randomized, controlled trial of computer-assisted cognitive remediation for schizophrenia", Am J Psychiatry, 167, pp.170~180 (2010)
- Strauss GP, "Attentional disengagement from emotional stimuli in schizophrenia", Schizophr Res, 131, pp.219~223 (2011)
- Sachs G, "Training of affect recognition (TAR) in schizophrenia-Impact on functional outcome", Schizophr Res (2012)[DOI]
- Cho BH, "The effect of virtual reality cognitive training for attention enhancement", CyberPsychology & Behavior, 5, pp.129~137 (2002)
- Posner MI, "The attention system of the human brain", Annu Rev Neurosci, 13, pp.25~42 (1990)
- Urbanek C, "Attention network test (ANT) reveals gender-specific alterations of executive function in schizophrenia", Psychiatry Res, 168, pp.102~109 (2009)
- Gooding DC, "Attentional network task performance in patients with schizophrenia-spectrum disorders: evidence of a specific deficit", Schizophr Res, 88, pp.169~178 (2006)
- Wang K, "Selective impairment of attentional networks of orienting and executive control in schizophrenia", Schizophr Res, 78, pp.235~241 (2005)
- Peer JE, "Social cognitive bias and neurocognitive deficit in paranoid symptoms: evidence for an interaction effect and changes during treatment", Schizophr Res, 71, pp.463~471 (2004)
- Cohen AS, "Neuropsychological functioning and social anhedonia: results from a community high-risk study", Schizophr Res, 85, pp.132~141 (2006)
- Tully LM, "Impaired executive control of emotional information in social anhedonia", Psychiatry Res (2012)[DOI]
- Tallent KA, "Working memory and Wisconsin Card Sorting Test performance in schizotypic individuals: a replication and extension", Psychiatry Res, 89, pp.161~170 (1999)
- Association AP, "DSM-IV. APATFo. Diagnostic and statistical manual of mental disorders: DSM-IV-TR" (2000), American Psychiatric Publishing, Inc
- Kay SR, "The positive and negative syndrome scale (PANSS) for schizophrenia", Schizophr Bull, 13, pp.261~276 (1987)
- Chapman LJ, "Scales for physical and social anhedonia", J Abnorm Psychol, 85, pp.374~382 (1976)
- Kratzmeier H, "Manual: Raven-Matrizen-Test, Standard Progressive Matrices: Weinheim" (1979), Beltz Test
- Lang PJ, "International affective picture system (IAPS): Technical manual and affective ratings: Gainesville, FL: The Center for Research in Psychophysiology" (1999), University of Florida
- Park IH, "Dysfunctional modulation of emotional interference in the medial prefrontal cortex in patients with schizophrenia", Neurosci Lett, 440, pp.119~124 (2008)
- Linden SC, "Emotion-cognition interactions in schizophrenia: Implicit and explicit effects of facial expression", Neuropsychologia, 48, pp.997~1002 (2010)
- Strauss GP, "Patterns of emotional experience in schizophrenia: Differences in emotional response to visual stimuli are associated with clinical presentation and functional outcome", Schizophr Res, 128, pp.117~123 (2011)
- Choi SH, "Deficits in eye gaze during negative social interactions in patients with schizophrenia", J Nerv Ment DIS, 198, pp.829~835 (2010)
- Modinos G, "Multivariate pattern classification reveals differential brain activation during emotional processing in individuals with psychosis proneness", Neuroimage, 59, pp.3033~3041 (2012)
- Paradiso S, "Cerebral blood flow changes associated with attribution of emotional valence to pleasant, unpleasant, and neutral visual stimuli in a PET study of normal subjects", Am J Psychiatry, 156, pp.1618~1629 (1999)
- Kerns JG, "Aberrant semantic and affective processing in people at risk for psychosis", J Abnorm Psychol, 109, pp.728~732 (2000)
- Hooker CI, "Can I trust you? Negative affective priming influences social judgments in schizophrenia", J Abnorm Psychol, 120, pp.98~107 (2011)
- Breton F, "The executive control of attention differentiates patients with schizophrenia, their first-degree relatives and healthy controls", Neuropsychologia, 49, pp.203~208 (2011)
- Posner MI, "Attentional mechanisms of borderline personality disorder", Proc Natl Acad Sci U S A, 99, pp.16366~16370 (2002)