본문 바로가기
KERD
논문KCI 등재

Variables Influencing Subjective Well-Being in Patients with Schizophrenia

2

조회

0

다운로드

0

인용

0

참고문헌

키워드

주제분류정신과학

초록

Objectives : The purpose of this study was to analyze the relationship between subjective well-being and other clinical parameters such as sociodemographic and clinical variables, which include positive and negative symptoms, depressive symptoms, insight, and side effects. Methods : Fifty-one outpatients diagnosed with schizophrenia were recruited in this study. Subjective well-being was assessed using a self-rating scale, the Subjective Well-being under Neuroleptics-Short form (SWN-K). Sociodemographic variables were also evaluated and other evaluations were conducted using the Positive and Negative Syndrome Scale (PANSS), Calgary Depression Scale for Schizophrenia (CDSS), Liverpool University Neuroleptic Side Effect Rating Scale (LUNSERS), Korean Version of the Revised Insight Scale for Psychosis (KISP), and Multidimensional Scale of Perceived Social Support (MSPSS). The relationship between subjective well-being and these clinical variables was assessed. Results : Education years and social support scores were positively correlated with the total SWN-K scores, but severity of illness, severity of depression, severity of side effect, and the scores on insight were negatively correlated. The stepwise multiple regression analyses indicated that the total SWN-K score of the patients with schizophrenia was associated with negative symptoms and insight. Conclusion : Better insight and more severe negative symptoms in patients with schizophrenia may be associated with worse subjective well-being. Results indicate that careful evaluation of subjective well-being is essential for proper management of patients with schizophrenia.

Abstract

Objectives : The purpose of this study was to analyze the relationship between subjective well-being and other clinical parameters such as sociodemographic and clinical variables, which include positive and negative symptoms, depressive symptoms, insight, and side effects. Methods : Fifty-one outpatients diagnosed with schizophrenia were recruited in this study. Subjective well-being was assessed using a self-rating scale, the Subjective Well-being under Neuroleptics-Short form (SWN-K). Sociodemographic variables were also evaluated and other evaluations were conducted using the Positive and Negative Syndrome Scale (PANSS), Calgary Depression Scale for Schizophrenia (CDSS), Liverpool University Neuroleptic Side Effect Rating Scale (LUNSERS), Korean Version of the Revised Insight Scale for Psychosis (KISP), and Multidimensional Scale of Perceived Social Support (MSPSS). The relationship between subjective well-being and these clinical variables was assessed. Results : Education years and social support scores were positively correlated with the total SWN-K scores, but severity of illness, severity of depression, severity of side effect, and the scores on insight were negatively correlated. The stepwise multiple regression analyses indicated that the total SWN-K score of the patients with schizophrenia was associated with negative symptoms and insight. Conclusion : Better insight and more severe negative symptoms in patients with schizophrenia may be associated with worse subjective well-being. Results indicate that careful evaluation of subjective well-being is essential for proper management of patients with schizophrenia.

참고문헌 (55)

  1. Carpenter WT, "Schizophrenia", N Engl J Med, 330, pp.681~690 (1994)
  2. Karow A, "Subjective well-being and quality of life under atypical antipsychotic treatment", Psychopharmacology (Berl), 162, pp.3~10 (2002)
  3. Narvaez JM, "Subjective and objective quality of life in schizophrenia", Schizophr Res, 98, pp.201~208 (2008)
  4. 김성완, "단축형 항정신병약물치료 중 주관적 안녕감 척도의 표준화 연구", 대한정신약물학회지, 18(4), pp.221~230 (2007), 대한정신약물학회
  5. Spilker B, "Quality of life and pharmacoeconomics in clinical trials", pp.11~24 (1996), Lippincott-Raven
  6. Bullinger M, "Evaluating quality-of-life measures for clin-ical trials in germany", Control Clin Trials, 12, pp.91~105 (1991)
  7. Lambert M, "Long-term patterns of subjective wellbeing in schizophrenia: cluster, predictors of cluster affiliation, and their re-lation to recovery criteria in 2842 patients followed over 3 years", Schizophr Res, 107, pp.165~172 (2009)
  8. Wehmeier PM, "Cor-relation of physician and patient rated quality of life during antipsy-chotic treatment in outpatients with schizophrenia", Schizophr Res, 91, pp.178~186
  9. Wehmeier PM, "Quality of life and subjective well-being during treatment with antipsychotics in out-patients with schizophrenia", Prog Neuro-psychopharmacol Biol Psychiatry, 31, pp.703~712 (2007)
  10. Lambert M, "Remission of severely impaired subjective wellbeing in 727 pa-tients with schizophrenia treated with amisulpride", Acta Psychiatr Scand, 115, pp.106~113 (2007)
  11. Karow A, "Association of subjective well-being, symptoms, and side effects with compliance after 12 months of treatment in schizophre-nia", J Clin Psychiatry, 68, pp.75~80 (2007)
  12. Perkins DO, "Predictors of antipsychotic medication adherence in patients recovering from a first psychotic episode", Schizophr Res, 83, pp.53~63 (2006)
  13. Heslegrave RJ, "The influence of neurocog-nitive deficits and symptoms on quality of life in schizophrenia", J Psychiatry Neurosci, 22, pp.235~ (1997)
  14. Lysaker PH, "Stig-ma, social function and symptoms in schizophrenia and schizoaffec-tive disorder: associations across 6 months", Psychiatry Res, 149, pp.89~ (2007)
  15. Galletly CA, "Relationships be-tween changes in symptom ratings, neuropsychological test per-formance and quality of life in schizophrenic patients treated with clozapine", Psychiatry Res, 72, pp.161~166 (1997)
  16. Packer S, "Psychopathology and quality of life in schizophrenia", J Psychiatry Neurosci, 22, pp.231~ (1997)
  17. Karow A, "Panss syn-dromes and quality of life in schizophrenia", Psychopathology, 38, pp.320~326 (2005)
  18. Huppert JD, "Quality of life in schizophrenia: contributions of anxiety and depression", Schizophr Res, 51, pp.171~180 (2001)
  19. Kim JH, "The relationship between depressive symptoms and subjective well-being in newly admitted patients with schizophrenia", Compr Psychiatry, 51, pp.165~170 (2010)
  20. Dickerson F, "Subjective quality of life in out-pa-tients with schizophrenia: clinical and utilization correlates", Acta Psychiatr Scand, 98, pp.124~127 (1998)
  21. Jung HY, "A validation study of korean-version of liverpool university neuro-leptic side effect rating scale (LUNSERS): liverpool university neu-roleptic side effect rating scale (LUNSERS)", J Korean Neuropsychiatr Assoc, 41, pp.138~145 (2002)
  22. 류석환, "정신분열병 환자의 삶의 질:항정신병 약물의 차이에 따른 주관적 삶의 질, 약물 태도와 약물 부작용의 관련성", 대한정신약물학회지, 16(1), pp.42~51 (2005), 대한정신약물학회
  23. Corrigan PW, "The construct validity of subjective quali-ty of life for the severely mentally ill", J Nerv Ment Dis, 183, pp.281~285 (1995)
  24. Ritsner M, "Predicting changes in domain-specific quality of life of schizophrenia patients", J Nerv Ment Dis, 191, pp.287~294 (2003)
  25. Ritsner M, "Differences in quality of life domains and psychopathologic and psychosocial factors in psychiatric patients", J Clin Psychiatry, 61, pp.880~889 (2000)
  26. Alptekin K, "quality of life associated with cognitive impairment in schizo-phrenia?", Prog Neuropsychopharmacol Biol Psychiatry, 29, pp.239~244 (2005)
  27. Matsui M, "Cognitive functioning related to quality of life in schizophrenia", Prog Neuro-psychopharmacol Biol Psychiatry, 32, pp.280~287 (2008)
  28. Karow A, "Insight and quality of life in schizophrenia: re-cent findings and treatment implications", Curr Opin Psychiatry, 19, pp.637~641 (2006)
  29. Sim K, "Subjective quality of life in first episode schizophrenia spectrum disorders with comorbid depression", Psychiatry Res, 129, pp.141~ (2004)
  30. Hasson-Ohayon I, "Insight into psychosis and quality of life", Compr Psychiatry, 47, pp.265~269 (2006)
  31. Naber D, "Improvement of schizophrenic patients’ subjective well-being under atypical antipsychotic drugs", Schizophr Res, 50, pp.79~88 (2001)
  32. Yoon JS, "The development of a korean modification of the scale to measure subjective well-being under neuroleptic treatment (KmSWN)", J Korean Neuropsychiatr Assoc, 39, pp.987~998 (2000)
  33. Naber D, "A self-rating to measure subjective effects of neuroleptic drugs, relationships to objective psychopathology, quality of life, compliance and other clinical variables", Int Clin Psychopharmacol, 10, pp.133~138 (1995)
  34. Kay SR, "The positive and negative syndrome scale (PANSS) for schizophrenia", Schizophr Bull, 13, pp.261~276 (1987)
  35. Kay SR, "The positive and negative syn-drome scale (PANSS): Rationale and standardisation", Br J Psychia-try Suppl, 155, pp.59~67 (1989)
  36. 이중서, "한국판 양성 및 음성증후군 척도(Positive and Negative Syndrome Scale)의 신뢰도와 타당도", 신경정신의학, 40(6), pp.1090~1105 (2001), 대한신경정신의학회
  37. Addington D, "A depression rating scale for schizophrenics", Schizophr Res, 3, pp.247~251 (1990)
  38. Addington D, "Reliability and validity of a depression rating scale for schizophrenics", Schizophr Res, 6, pp.201~208 (1992)
  39. Kim JH, "Assessing the reliability and validity of the korean version of the revised insight scale for psychosis (KISP)", Schizophr Clinics, 7, pp.15~21 (2004)
  40. Hogan T, "Subjective response to neuroleptics and outcome in schizophrenia: A re-examination comparing two measures", Psy-chol Med, 22, pp.347~352 (1992)
  41. 윤보현, "한국판 약물태도 척도의 심리측정적 특성", 대한정신약물학회지, 16(6), pp.480~487 (2005), 대한정신약물학회
  42. Eker D, "Perceived social support: Psychometric proper-ties of the mspss in normal and pathological groups in a developing country", Soc Psychiatry Psychiatr Epidemiol, 30, pp.121~126 (1995)
  43. Cardoso CS, "Factors associated with low quality of life in schizo-phrenia", Cad Saude Publica, 21, pp.1338~1340 (2005)
  44. Röder-Wanner UU, "Does quality of life differ in schizophrenic women and men? An empirical study", Int J Soc Psychiatry, 43, pp.129~143 (1997)
  45. Koivumaa-Honkanen HT, "Correlates of life satisfaction among psychiatric patients", Acta Psychiatr Scand, 94, pp.372~378 (1996)
  46. Huber G, "A long-term follow-up study of schizo-phrenia: psychiatric course of illness and prognosis", Acta Psychiatr Scand, 52, pp.49~57 (1975)
  47. Cobb S, "Presidential address-1976. Social support as a moderator of life stress", Psychosom Med, 38, pp.300~314 (1976)
  48. 양동석, "정신장애 환자와 보호자의 사회인구학적, 임상적 및 심리적 특성과 삶의 질의 관계", 신경정신의학, 40(6), pp.1044~1054 (2001), 대한신경정신의학회
  49. Yoo HJ, "Quality of life and in-sight in patients with schizophrenia", J Korean Neuropsychiatr Assoc, 38, pp.340~348 (1999)
  50. Ho BC, "Two-year outcome in first-episode schizophrenia: predictive value of symp-toms for quality of life", Am J Psychiatry, 155, pp.1196~1201 (1998)
  51. De Haan L, "Psy-chometric properties of the subjective well-being under neurolep-tics scale and the subjective deficit syndrome scale", Psychopharmacology (Berl), 162, pp.24~28 (2002)
  52. 김경진, "정신분열병 환자의 삶의 질과 정신사회적 특성과의 관계", 신경정신의학, 43(5), pp.603~610 (2004), 대한신경정신의학회
  53. Kim EK, "Effect of clozapine on the quality of life in treatment-resistant schizophrenic patients", J Korean Neuropsychiatr Assoc, 38, pp.1447~1458 (1999)
  54. Pinikahana J, "Quality of life in schizo-phrenia: a review of the literature from 1995 to 2000", Int J Ment Health Nurs, 11, pp.103~111 (2000)
  55. 서호석, "정신분열병 환자의 삶의 질과 정신병리:주관 및 객관적 평가", 신경정신의학, 40(6), pp.1122~1131 (2001), 대한신경정신의학회

관련 논문AI추천

Subjective Well-being in Patients with Schizophrenia Treated with Atypical Antipsychotics: The Impact of Psychopathology and Adverse Drug Effects김종훈, 배승민, 조인희, Jinyoung Lee, Jun-Hyung Ann, Min-Jung Kim, Seo-Eun Cho, Seog Ju Kim, Seong-Jin Cho, Yeon-Woo Lee, Yu-Jin Lee대한정신약물학회 · Clinical Psychopharmacology and Neuroscience2010 · 제8권 제3호조현병 환자에서 심리사회적 요인, 인지 기능, 정신병리와 병식의 관계김승현, 백종우, 어다솜, 이문수, 한창수대한조현병학회 · 대한조현병학회지2015 · 제18권 제2호조현병 환자에서 가족관계와 삶의 질의 관계김선영, 김성완, 김재민, 윤진상, 이주연, 정하란, 강한고은비대한생물치료정신의학회 · 생물치료정신의학2018 · 제24권 제3호노인 만성 조현병 환자군에서 병태생리, 인지기능, 병식, 삶의 질 간의 관련성김정민, 나의현, 이준노, 임선진, 한혜리, 홍경기, 홍문화대한노인정신의학회 · 노인정신의학2014 · 제18권 제2호정신분열증의 정신증 후 우울장애의 예측인자구본훈, 김이영, 김정엽, 김진성, 배대석, 서완석, 이종범영남대학교 의과대학 · Journal of Yeungnam Medical Science2005 · 제22권 제2호조현병 환자에서의 삶의 질을 결정하는 요인 : 회복탄력성을 중심으로김민숙, 우은송, 정재오, 최영민대한신경정신의학회 · 신경정신의학2016 · 제55권 제4호

이 간행물의 다른 논문 (5건)