약물 전달 시스템의 네트워크 연구: 마이크로니들과 피부
A Study on Networks for Drug Delivery Systems: Microneedle and Skin
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초록
치료약물은 경구, 주사, 경피, 비강, 폐를 통하여 주입할 수 있으나 많은 부작용을 가지고 있다. 약물전달시스템은 약물이 가지고 있는 부작용을 줄이고 효율성을 증가시키기 위하여 최근에 개발되고 한단계 진전된 방법으로 원하는 부위에 치료약물을 효과적으로 전달할 수 있다. 다양한 약물전달시스템 방법들 중에 마이크로니들 치료시스템은 고통 없이 피부에 약물을 효과적으로 주입하는 방법으로 의약과 피부미용 분야에서 발달되고 있다. 이 논문에서는, 약물전달시스템과 마이크로니들치료시스템의 기본적인 개념에 대하여 소개하고, 이와 함께 피부의 구조와 기능을 기술하여 마이크로니들을 제조하고 연구하는 이 분야의 연구자들에게 도움이 되도록 하여 새로운 기술의 발전이 가능하도록 하였다.
Abstract
Drug can be administered through oral. parenteral, transdermal, nasal, and pulmonary route, but each have its owndisadvantage. The drug delivery system(DDS) is an advanced technology that effectively delivers therapeutic drugs to desiredtargets and thereby reduces side effects and increase efficacy. Microneedle therapy system(MTS) is advancing in the field ofmedicine and skin care which can improve drug diffusion into skin with no pain. In this study, we introduce the basicconcepts of DDS and MTS including the structure and function of skin, so that researchers may benefit in their attentionon the production of microneedle and promoting research on the area.
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