섬유성 이형성증을 모방한 상악동 미만성 거대 B세포 림프종 1예
A Case of Diffuse Large B Cell Lymphoma on Maxillaly Sinus Mimicking Fibrous Dysplasia
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A 38-year-old male came to outpatient clinic, presenting with a 1-month history of headache and right facial pain. There was no specific finding on nasal endoscopy. Paranasal sinuses computed tomography (PNS CT) showed unilateral soft tissue density on right maxillary sinus and ground glass opacity on right maxillary and zygomatic bone. And there was no finding suggestive of malignancy in the subsequent PNS magnetic resonance imaging (MRI). We considered benign tumor such as fibrous dysplasia with maxillary sinusitis and performed the endoscopic sinus surgery combined with open surgery via Caldwell-Luc and subcillary approach. Histopathological diagnosis was diffuse large B-cell lymphoma. After six cycles of rituximab, cyclophosphamide, doxorubicin, vincristine, prednisolone chemotherapy, he gained complete remission and found no recurrence until two years. We report a rare case of sinonasal lymphoma mimicking fibrous dysplasia with literature review.
Abstract
A 38-year-old male came to outpatient clinic, presenting with a 1-month history of headache and right facial pain. There was no specific finding on nasal endoscopy. Paranasal sinuses computed tomography (PNS CT) showed unilateral soft tissue density on right maxillary sinus and ground glass opacity on right maxillary and zygomatic bone. And there was no finding suggestive of malignancy in the subsequent PNS magnetic resonance imaging (MRI). We considered benign tumor such as fibrous dysplasia with maxillary sinusitis and performed the endoscopic sinus surgery combined with open surgery via Caldwell-Luc and subcillary approach. Histopathological diagnosis was diffuse large B-cell lymphoma. After six cycles of rituximab, cyclophosphamide, doxorubicin, vincristine, prednisolone chemotherapy, he gained complete remission and found no recurrence until two years. We report a rare case of sinonasal lymphoma mimicking fibrous dysplasia with literature review.
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