재발성 후각신경아세포종 환자에서의 감마나이프수술 1예
Gamma Knife Radiosurgery for Recurrent Olfactory Neuroblastoma: A Case Report
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The olfactory neuroblastoma (ONB) is a rare malignant tumor that arises in the nasal cavity and paranasal sinuses. The most common treatment is the craniofacial resection, but recently endoscopic resection has been used as an initial treatment to reduce complications. In addition, depending on the stage of the disease, radiation therapy or chemotherapy can be performed before or after surgery. ONB can also recur, showing two patterns of recurrence: local recurrence and distant metastasis to cervical lymph nodes and lungs. Local recurrence is usually treated with craniotomy, but this is an invasive treatment method that can cause various complications. Therefore, non-invasive treatment methods such as stereotactic radiation therapy are now being considered. The authors report a recurred ONB case successfully treated with Gamma knife radiosurgery without craniofacial resection, as the patient showed delayed bilateral cervical lymph node metastasis and suspected recurrent intracranial invasion after treatment.
Abstract
The olfactory neuroblastoma (ONB) is a rare malignant tumor that arises in the nasal cavity and paranasal sinuses. The most common treatment is the craniofacial resection, but recently endoscopic resection has been used as an initial treatment to reduce complications. In addition, depending on the stage of the disease, radiation therapy or chemotherapy can be performed before or after surgery. ONB can also recur, showing two patterns of recurrence: local recurrence and distant metastasis to cervical lymph nodes and lungs. Local recurrence is usually treated with craniotomy, but this is an invasive treatment method that can cause various complications. Therefore, non-invasive treatment methods such as stereotactic radiation therapy are now being considered. The authors report a recurred ONB case successfully treated with Gamma knife radiosurgery without craniofacial resection, as the patient showed delayed bilateral cervical lymph node metastasis and suspected recurrent intracranial invasion after treatment.
참고문헌 (14)
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