본문 바로가기
KERD
논문KCI 등재

폐쇄성 수면 무호흡증 환자의 REM(Rapid Eye Movement) 및 NREM(Non- Rapid Eye Movement) 수면에서 코골이 소리의 음향학적 분석

Acoustic Analysis of Snoring Sounds in Rapid Eye Movement (REM) and Non-Rapid Eye Movement (NREM) (N2) Sleep in OSAS patients

2

조회

0

다운로드

0

인용

0

참고문헌

키워드

주제분류이비인후과학

초록

Background and Objectives: Although there are many stages of sleep, there are few studies on the differences in snoring sounds that occur in each stage of sleep. Acoustic analysis of snoring sounds provides a lot of information, and in this study, we attempted to acoustically analyze and compare snoring sounds generated during rapid eye movement (REM) sleep and non-REM (NREM) sleep. Materials and Methods: Thirteen with obstructive sleep apnea who underwent polysomnography were enrolled. Snoring sounds were analyzed during REM and NREM (N2 stage) sleep using a recorder placed within 30 cm of the shoulders. To eliminate confounding factors associated with sleeping position, the snoring sounds were recorded only in the supine position. In addition, to prevent inter-examiner errors, the recordings were performed by a single person. Snoring sounds were compared between sleep stages for formant frequency (Hz), intensity (dB), and spectrogram. Results: Formant frequency analysis of snoring sounds revealed statistically significant F2 values generated during REM and NREM (N2) sleep in males (p<0.05). The intensity of snoring sounds (dB) was significantly higher in men than in women during REM sleep (p<0.05). A 0.025-narrow-band spectrogram analysis revealed that the intensity waveform of snoring was darker and exhibited higher energy densities in REM sleep than in NREM (N2) sleep. Conclusion: There was an acoustic difference between the snoring sound generated during REM sleep and NREM (N2) sleep, and further studies with more cases should be conducted.

Abstract

Background and Objectives: Although there are many stages of sleep, there are few studies on the differences in snoring sounds that occur in each stage of sleep. Acoustic analysis of snoring sounds provides a lot of information, and in this study, we attempted to acoustically analyze and compare snoring sounds generated during rapid eye movement (REM) sleep and non-REM (NREM) sleep. Materials and Methods: Thirteen with obstructive sleep apnea who underwent polysomnography were enrolled. Snoring sounds were analyzed during REM and NREM (N2 stage) sleep using a recorder placed within 30 cm of the shoulders. To eliminate confounding factors associated with sleeping position, the snoring sounds were recorded only in the supine position. In addition, to prevent inter-examiner errors, the recordings were performed by a single person. Snoring sounds were compared between sleep stages for formant frequency (Hz), intensity (dB), and spectrogram. Results: Formant frequency analysis of snoring sounds revealed statistically significant F2 values generated during REM and NREM (N2) sleep in males (p<0.05). The intensity of snoring sounds (dB) was significantly higher in men than in women during REM sleep (p<0.05). A 0.025-narrow-band spectrogram analysis revealed that the intensity waveform of snoring was darker and exhibited higher energy densities in REM sleep than in NREM (N2) sleep. Conclusion: There was an acoustic difference between the snoring sound generated during REM sleep and NREM (N2) sleep, and further studies with more cases should be conducted.

참고문헌 (20)

  1. Punjabi NM, "The epidemiology of adult obstructive sleep apnea", Proc Am Thorac Soc, 5(2), pp.136~143 (2008)
  2. Ben-Israel N, "Obstructive apnea hypopnea index estimation by analysis of nocturnal snoring signals in adults", Sleep, 35(9), pp.1299~1305 (2012)
  3. Van de Water ATM, "Objective measurements of sleep for non-laboratory settings as alternatives to polysomnography : a systematic review", J Sleep Res, 20(1pt2), pp.183~200 (2011)
  4. Akhter S, "Snore sound analysis can detect the presence of obstructive sleep apnea specific to NREM or REM sleep", J Clin Sleep Med, 14(6), pp.991~1003 (2018)
  5. Orem J, "Physiology in sleep" (2012), Elsevier
  6. Flexer A, "A reliable probabilistic sleep stager based on a single EEG signal", Artif Intell Med, 33(3), pp.199~207 (2005)
  7. Akhter S, "Characterizing the NREM", REM sleep specific obstructive sleep apnea severity using snore sounds, 2017, 2826~2829
  8. Beck R, "The acoustic properties of snores", Eur Respir J, 8(12), pp.2120~2128 (1995)
  9. Van Brunt DL, "Intensity pattern of snoring sounds as a predictor for sleep-disordered breathing", Sleep, 20(12), pp.1151~1156 (1997)
  10. Fiz JA, "Acoustic analysis of snoring sound in patients with simple snoring and obstructive sleep apnoea", Eur Respir J, 9(11), pp.2365~2370 (1996)
  11. Bliwise DL, "Relative validity of self-reported snoring as a symptom of sleep apnea in a sleep clinic population", Chest, 99(3), pp.600~608 (1991)
  12. Sola-Soler J, "Pitch analysis in snoring signals from simple snorers and patients with obstructive sleep apnea", Proceedings of the Second Joint 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society. Engineering in Medicine and Biology, pp.1527~1528 (2002)
  13. Oksenberg A, "The effect of body posture on sleep-related breathing disorders : facts and therapeutic implications", Sleep Med Rev, 2(3), pp.139~162 (1998)
  14. Jané R, "Snoring analysis for the screening of sleep apnea hypopnea syndrome with a single-channel device developed using polysomnographic and snoring databases", Annu Int Conf IEEE Eng Med Biol Soc, 2011, pp.8331~8333 (2011)
  15. American Academy of Sleep Medicine Task Force, "Sleep-related breathing disorders in adults : recommendations for syndrome definition and measurement techniques in clinical research. The report of an American Academy of Sleep Medicine Task Force", Sleep, 22(5), pp.667~689 (1999)
  16. Grace KP, "Identification of the mechanism mediating genioglossus muscle suppression in REM sleep", Am J Respir Crit Care Med, 187(3), pp.311~319 (2013)
  17. Peppard PE, "The impact of obesity on oxygen desaturation during sleep-disordered breathing", Am J Respir Crit Care Med, 180(8), pp.788~793 (2009)
  18. Schäffer T, "Respiratory physiology in sleep and wakefulness", Handb Clin Neurol, 98, pp.371~381 (2011)
  19. Nakano H, "Effects of body position on snoring in apneic and nonapneic snorers", Sleep, 26(2), pp.169~172 (2003)
  20. Wiegand DA, "Upper airway resistance and geniohyoid muscle activity in normal men during wakefulness and sleep", J Appl Physiol, 69(4), pp.1252~1261 (1990)

관련 논문AI추천

Snoring Sound Intensity and Formant Frequencies by Sleep Position in Patients with Positional Obstructive Sleep Apnea고태경, 구수권, 권순복, 박근형, 이상준, 이호병, 지창록대한이비인후과학회 · 대한이비인후과학회지 두경부외과학2020 · 제63권 제7호폐쇄성 무호흡증 환자에서 코골이 시간(%)의 임상적 의의강태욱, 김경래, 김선욱, 성의숙, 윤병기, 조석현, 최지혜대한이비인후과학회 · 대한이비인후과학회지 두경부외과학2016 · 제59권 제9호Does Rapid Eye Movement Sleep Aggravate Obstructive Sleep Apnea?김성희, 김천식, 백종태, 양찬주, 이상암, 정유삼, 현상민대한이비인후과학회 · Clinical and Experimental Otorhinolaryngology2019 · 제12권 제2호한국 성인에서 렘수면의존폐쇄수면무호흡증 환자의임상양상김도형, 김동은, 문혜진, 임상훈, 조용원, 황상희대한신경과학회 · 대한신경과학회지2016 · 제34권 제2호폐쇄성 수면 무호흡 환자에서 수면 다원 검사 결과의 성별 차이강현우, 이래형, 이승주대한이비인후과학회 · 대한이비인후과학회지 두경부외과학2012 · 제55권 제2호The Severity of Sleep Disordered Breathing Induces Different Decrease in the Oxygen Saturation During Rapid Eye Movement and Non-Rapid Eye Movement Sleep박두흠, 유승호, 유재학, 최은경, 하지현대한신경정신의학회 · PSYCHIATRY INVESTIGATION2016 · 제13권 제6호

이 간행물의 다른 논문 (6건)