전정신경염에서 추골동맥 병변의 임상적 의의
The Clinical Significance of Vertebral Artery Lesions in Vestibular Neuritis
2
조회
0
다운로드
1
인용
0
참고문헌
키워드
초록
Background and Objectives: The etiology of vestibular neuritis (VN) is elusive, however viral infection and vascular ischemia are considered as major cause of VN. The aims of the present study were to evaluate relationships between vertebrobasilar artery status and VN. Materials and Methods: Patients who received treatment for VN from April 2014 to October 2019 were enrolled. All subjects underwent vestibular function tests of caloric test, cervical vestibular evoked myogenic potential test and magnetic resonance imaging (MRI) angiography. Vertebral artery (VA) lesions were defined as vertebral hypoplasia and vertebral stenosis. Results: A total of 130 patients were diagnosed as VN and completed MRI angiography. 12 patients had VA abnormalities (9.23%). 9/12 patients (75.0%) had same lesion side of VN and VA lesions (p=0.098). Hospitalization period, duration of dizziness and duration of spontaneous nystagmus between normal VA group and abnormal VA group had no significant difference. However, duration of spontaneous nystagmus considering only abnormal caloric test group was significantly lower in abnormal VA group than normal VA group (p=0.001). Conclusion: The present study suggested that VA disorder might have relationship with VN, as vascular factor is one of the most common reasons for VN. Moreover, spontaneous nystagmus recovers faster in patients with VA disorder.
Abstract
Background and Objectives: The etiology of vestibular neuritis (VN) is elusive, however viral infection and vascular ischemia are considered as major cause of VN. The aims of the present study were to evaluate relationships between vertebrobasilar artery status and VN. Materials and Methods: Patients who received treatment for VN from April 2014 to October 2019 were enrolled. All subjects underwent vestibular function tests of caloric test, cervical vestibular evoked myogenic potential test and magnetic resonance imaging (MRI) angiography. Vertebral artery (VA) lesions were defined as vertebral hypoplasia and vertebral stenosis. Results: A total of 130 patients were diagnosed as VN and completed MRI angiography. 12 patients had VA abnormalities (9.23%). 9/12 patients (75.0%) had same lesion side of VN and VA lesions (p=0.098). Hospitalization period, duration of dizziness and duration of spontaneous nystagmus between normal VA group and abnormal VA group had no significant difference. However, duration of spontaneous nystagmus considering only abnormal caloric test group was significantly lower in abnormal VA group than normal VA group (p=0.001). Conclusion: The present study suggested that VA disorder might have relationship with VN, as vascular factor is one of the most common reasons for VN. Moreover, spontaneous nystagmus recovers faster in patients with VA disorder.
참고문헌 (20)
- Jeong SH, "Vestibular neuritis", Semin Neurol, 33(3), pp.185~194 (2013)
- Ahn SH, "Final diagnosis of patients with clinically suspected vestibular neuritis showing normal caloric response", J Clin Neurosci, 41, pp.107~110 (2017)
- Le TN, "Vestibular neuritis : recent advances in etiology, diagnostic evaluation, and treatment", Adv Otorhinolaryngol, 82, pp.87~92 (2019)
- Hegemann SCA, "Diagnosis and treatment of vestibular neuritis", neuronitis or peripheral vestibulopathy (PVP)? Open questions and possible answers, 2017, pp.38(5), 626~631
- Milionis HJ, "Lipoprotein(a)and acute-phase response in patients with vestibular neuronitis", Eur J Clin Invest, 33(12), pp.1045~1050 (2003)
- Chuang YM, "The clinical relevance of vertebral artery hypoplasia", Acta Neurol Taiwan, 21(1), pp.1~7 (2012)
- 김현지, "Vestibular Neuritis With Minimal Canal Paresis: Characteristics and Clinical Implication", Clinical and Experimental Otorhinolaryngology, 10(2), pp.148~152 (2017), 대한이비인후과학회[DOI]
- Jongkees LB, "Clinical nystagmography:a detailed study of electro-nystagmography in 341 patients with vertigo", Pract Otorhinolaryngol(Basel), 24(3), pp.65~93 (1962)
- Oh HG, "Clinical significance of vertebral artery hypoplasia in lateral medullary infarction", J Neurol Sci, 333, pp.E201~ (2013)
- Himmelein S, "Differential involvement during latent herpes simplex virus 1 infection of the superior and inferior divisions of the vestibular ganglia : implications for vestibular neuritis", J Virol, 91(14), pp.e00331-17~ (2017)
- Greco A, "Is vestibular neuritis an immune related vestibular neuropathy inducing vertigo?", J Immunol Res, 2014, pp.459048~ (2014)
- Hsu YH, "Association of sudden sensorineural hearing loss with vertebrobasilar insufficiency", JAMA Otolaryngol Head Neck Surg, 142(7), pp.672~675 (2016)
- Hendrix P, "Blood supply of the cranial nerves", Nerves Nerve Inj, pp.427~438 (2015)
- 김고운, "전구증상으로 급성 내이기능 장애가 발현된 척추동맥 협착에 의한 일과성 허혈발작", 대한이비인후-두경부외과학회지, 59(1), pp.58~63 (2016), 대한이비인후과학회[DOI]
- Chung WK, "A case of acute labyrinthine infarction by vertebrobasilar insufficiency", Korean J Otorhinolaryngol Head Neck Surg, 41(12), pp.1604~1609 (1998)
- Hartkamp NS, "In vivo visualization of the PICA perfusion territory with super-selective pseudo-continuous arterial spin labeling MRI", Neuroimage, 83, pp.58~65 (2013)
- Ismail EI, "Corticosteroids versus vestibular rehabilitation in long-term outcomes in vestibular neuritis", J Vestib Res, 28(5-6), pp.417~424 (2018)
- Goudakos JK, "Corticosteroids and vestibular exercises in vestibular neuritis : single-blind randomized clinical trial", JAMA Otolaryngol Head Neck Surg, 140(5), pp.434~440 (2014)
- Lee JY, "Clinical characteristics of acute vestibular neuritis according to involvement site", Otol Neurotol, 40(6), pp.797~805 (2019)
- "Vertebrobasilar insufficiency" (2022)[URL]
