정신분열병에 대한 분자유전학적 연구의 현황과 앞으로의 방향

키워드

참고문헌 (99)

1. "The strength of the genetic effect Is there room for an environmental influence in the aetiology of schizophrenia", pp.593~9
2. "The molecular genetics of schizophrenia:new findings promise new insights", 9(1), pp.14~27 (2004)
3. "Searching for schizophrenia genes", 7, pp.169~74 (2001)
4. "Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease", 349, pp.704~6 (1991)
5. "Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease", 375, pp.754~60 (1995)
6. "Candidate gene for the chromosome 1 familial Alzheimer's disease locus", 269, pp.973~7 (1995)
7. "Genetics of Mental Disorders", pp.46~92 (1999), Guilford Press
8. "Is there really a split in schizophrenia?The genetic evidence", 150, pp.581~92 (1987)
9. "Additional support for schizophrenia linkage on chromosomes 6 and 8 Schizophrenia Linkage Collaborative Group for Chromosomes 3", pp.6 580~94, a multicenter study
10. "A combined analysis of D22S278 marker alleles in affected sib-pairs support for a susceptibility locus for schizophrenia at chromosome 22q12", pp.40~22 5
11. "Multicenter linkage study of schizophrenia candidate regions on chromosomes 5q", pp.652~63
12. "Suggestive evidence for linkage of schizophrenia to markers on chromosome 13q14", 5, pp.117~26 (1995)
13. "Schizophrenia susceptibility loci on chromosomes 13q32 and 8p21", 20, pp.70~3 (1998)
14. "Linkage of familial schizophrenia to chromosome 13q32", 65, pp.1096~103 (1999)
15. "Genomewide multipoint linkage analysis of seven extended Palauan pedigrees with schizophrenia,by a Markov-chain Monte Carlo method", 69, pp.1278~89 (2001)
16. "A genome-wide autosomal screen for schizophrenia susceptibility loci in 71 families with affected siblings:support for loci on chromosome 10p and 6", 5, pp.638~49 (2000)
17. "Support for a possible schizophrenia vulnerability locus in region 5q22-31 in Irish families", 2, pp.148~55 (1997)
18. "Genomewide genetic linkage analysis confirms the presence of susceptibility loci for schizophrenia and 8p21-22 and provides support for linkage to schizophrenia", pp.3 1 661~11 73
19. "Evidence suggestive of a locus on chromosome 5q31 contributing to susceptibility for schizophrenia in German and Israeli families by multipoint affected sib-pair linkage analysis", 2, pp.156~60 (1997)
20. "Genome scan of European-American schizophrenia pedigrees:results of the NIMH Genetics Initiative and Millennium Consortium", 81, pp.290~5 (1998)
21. "A schizophrenia locus may be located in region 10p15-p11", 81, pp.296~301 (1998)
22. "Location of a major susceptibility locus for familial schizophrenia on chromosome 1q21-q22", 288, pp.678~82 (2000)
23. "Susceptibility loci for bipolar disorder:overlap with inherited vulnerability to schizophrenia", 47, pp.245~51 (2000)
24. "Genome scan meta-analysis of schizophrenia and bipolar disorder,part II:Schizophrenia", 73, pp.34~48 (2003)
25. "Meta-analysis of whole-genome linkage scans of bipolar disorder and schizophrenia", 7, pp.405~11 (2002)
26. "Determination of the genomic structure and mutation screening in schizophrenic individuals for five subunits of the N-methyl-D-aspartate glutamate receptor", 7, pp.508~14 (2002)
27. "Positive association between a DNA sequence variant in the serotonin 2A receptor gene and schizophrenia", 67, pp.103~5 (1996)
28. "Association between schizophrenia and T102C polymorphism of the 5-hydroxytryptamine type 2a-receptor gene European Multicentre Association Study of Schizophrenia", (then mm), pp.1294~6
29. "Meta-analysis of association between the 5-HT2a receptor T102C polymorphism and schizophrenia European Multicentre Association Study of Schizophrenia", (then m)
30. "Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease", 33, pp.177~82 (2003)
31. "The serotonin-2A receptor gene locus does not contain common polymorphism affecting mRNA levels in adult brain", 9, pp.109~14 (2004)
32. "A functional polymorphism in the promoter region of the dopamine D2 receptor gene is associated with schizophrenia", 6, pp.577~82 (1997)
33. "Functional polymorphism of -141C Ins", Del in the dopamine D2 receptor gene promoter and schizophrenia, 1998, pp.81, 117~23
34. "Association between a promoter polymorphism in the dopamine D2 receptor gene and schizophrenia", 40, pp.31~6 (1999)
35. "Association between schizophrenia and homozygosity at the dopamine D3 receptor gene", 29, pp.858~60 (1992)
36. "A meta-analysis and transmission disequilibrium study of association between the dopamine D3 receptor gene and schizophrenia", 3, pp.141~9 (1998)
37. "Genetic variation in the 6p22 the human ortholog of the mouse dysbindin gene is associated with schizophrenia", pp.337~48
38. "Neuregulin 1 and susceptibility to schizophrenia", 71, pp.877~92 (2002)
39. "A potential vulnerability locus for schizophrenia on chromosome 6p24-22:evidence for genetic heterogeneity", 11, pp.287~93 (1995)
40. "Support for association of schizophrenia with genetic variation in the 6p22 in sib-pair families with linkage and in an additional sample of triad families"
41. with schizophrenia in an Irish population-based study, , 2003, 167~72
42. "Identification in 2 independent samples of a novel schizophrenia risk haplotype of the dystrobrevin binding protein gene(DTNBP1)", 61, pp.336~44 (2004)
43. "Association of neuregulin 1 with schizophrenia confirmed in a Scottish population", 72, pp.83~7 (2003)
44. "Glial growth factor", neuregulin inhibits Schwann cell myelination and induces demyelination, 2001, pp.152, 1289~99
45. "Cell death in the Schwann cell lineage and its regulation by neuregulin", 93, pp.9229~34 (1996)
46. "GGF", neuregulin is a neuronal signal that promotes the proliferation and survival and inhibits the differentiation of oligodendrocyte progenitors, 1996, pp.17, 229~43
47. "White matter changes in schizophrenia:evidence for myelin-related dysfunction", 60, pp.443~56 (2003)
48. "The glial growth factors deficiency and synaptic destabilization hypothesis of schizophrenia", 2, pp.8~ (2002)
49. "Genetic and physiological data implicating the new human gene G72 and the gene for D-amino acid oxidase in schizophrenia", 99, pp.13675~80 (2002)
50. "D-serine and serine racemase are present in the vertebrate retina and contribute to the physiological activation of NMDA receptors", 100, pp.6789~94 (2003)
51. "Free D-serine in post-mortem brains and spinal cords of individuals with and without neuropsychiatric diseases", 681, pp.117~25 (1995)
52. "Decreased serum levels of D-serine in patients with schizophrenia:evidence in support of the N-methyl-D-aspartate receptor hypofunction hypothesis of schizophrenia", 60, pp.572~6 (2003)
53. "Association and linkage analyses of RGS4 polymorphisms in schizophrenia", 11, pp.1373~80 (2002)
54. "Analysis of complex brain disorders with gene expression microarrays:schizophrenia as a disease of the synapse", 24, pp.479~86 (2001)
55. "Disease-specific changes in regulator of G-protein signaling 4(RGS4)expression in schizophrenia", 6, pp.293~301 (2001)
56. "Characterization of membrane-bound and soluble catechol-O-methyltransferase from human frontal cortex", 42, pp.826~32 (1984)
57. "Soluble and particulate forms of rat catechol-O-methyltransferase distinguished by gel electrophoresis and immune fixation", 44, pp.421~32 (1985)
58. "Genomic organization of the human catechol O-methyltransferase gene and its expression from two distinct promoters", 223, pp.1049~59 (1994)
59. "Human catechol-O-methyltransferase pharmacogenetics:description of a functional polymorphism and its potential application to neuropsychiatric disorders", 6, pp.243~50 (1996)
60. "Kinetics of human soluble and membrane-bound catechol O-methyltransferase:a revised mechanism and description of the thermolabile variant of the enzyme", 34, pp.4202~10 (1995)
61. "No evidence for allelic association between schizophrenia and a polymorphism determining high or low catechol O-methyltransferase activity", 153, pp.268~70 (1996)
62. "Association analysis of a functional catechol-o-methyltransferase gene polymorphism in schizophrenic patients in Taiwan", 43, pp.11~4 (2001)
63. "Association study of a functional catechol-O-methyltransferase gene polymorphism in Japanese schizophrenics", 243, pp.109~12 (1998)
64. "Preferential transmission of the high activity allele of COMT in schizophrenia", 6, pp.131~3 (1996)
65. "Catechol-O-methyltransferase polymorphisms and schizophrenia:a transmission disequilibrium study in multiply affected families", 7, pp.97~101 (1997)
66. "Effect of COMT Val108", 158 Met genotype on frontal lobe function and risk for schizophrenia, 2001, pp.98, 6917~22
67. "A functional polymorphism in the COMT gene and performance on a test of prefrontal cognition", 159, pp.652~4 (2002)
68. "A highly significant association between a COMT haplotype and schizophrenia", 71, pp.1296~302 (2002)
69. "Genetic variation at the 22q11 PRODH2", DGCR6 locus presents an unusual pattern and increases susceptibility to schizophrenia, 2002, pp.99, 3717~22
70. "The gene encoding proline dehydrogenase modulates sensorimotor gating in mice", 21, pp.434~9 (1999)
71. "Korean version of the diagnostic interview for genetic studies:Validity and reliability", 45, pp.225~9 (2004)
72. "No evidence for interaction between 5-HT2A receptor and serotonin transporter genes in schizophrenia", 52, pp.195~9 (2005)
73. "Polymorphism of the serotonin transporter gene and symptomatic dimensions of schizophrenia in the Korean population", 47, pp.182~6 (2003)
74. "Association of aggressive behavior in Korean male schizophrenic patients with polymorphisms in the serotonin transporter promoter and catecholamine-O-methyltransferase genes", 129, pp.29~37 (2004)
75. "Association of the Ser9Gly polymorphism in the dopamine D3 receptor gene with tardive dyskinesia in Korean schizophrenics", 56, pp.469~74 (2002)
76. "Gender-specific molecular heterosis of dopamine D2 receptor gene(DRD2)for smoking in schizophrenia", 114, pp.593~7 (2002)
77. "Association study of dopamine transporter gene and schizophrenia in Korean population using multiple single nucleotide polymorphism markers", 28, pp.975~83 (2004)
78. "Functional catechol-O-methyltransferase gene polymorphism and susceptibility to schizophrenia", 12, pp.299~303 (2002)
79. "Association of Ala72Ser polymorphism with COMT enzyme activity and the risk of schizophrenia in Koreans", 116, pp.319~28 (2005)
80. "Apolipoprotein E genotype in Korean schizophrenic patients", 16, pp.781~3 (2001)
81. "Report on IL-10 gene polymorphism at position -819 for major depression and schizophrenia in Korean population", 56, pp.177~80 (2002)
82. "Interleukin-10 gene promoter polymorphism is not associated with schizophrenia in the Korean population", 57, pp.153~9 (2003)
83. "Polymorphisms of interleukin-4 promoter and receptor gene for schizophrenia in the Korean population", 57, pp.283~8 (2003)
84. "Polymorphism of CTLA-4 gene at position 49 of exon 1 may be associated with schizophrenia in the Korean population", 110, pp.19~25 (2002)
85. "TNFB polymorphism may be associated with schizophrenia in the Korean population", 61, pp.39~45 (2003)
86. "Tumor necrosis factor-alpha gene polymorphism at position -308 and schizophrenia in the Korean population", 57, pp.399~403 (2003)
87. "Association study between glutathione S-transferase P1 polymorphism and schizophrenia in the Korean population", 27, pp.519~23 (2003)
88. "Glutathione S-transferase M1 polymorphism may contribute to schizophrenia in the Korean population", 14, pp.147~50 (2004)
89. "VNTR polymorphism of tyrosine hydroxylase gene and schizophrenia in the Korean population", 47, pp.131~6 (2003)
90. "Differences in p53 gene polymorphisms between Korean schizophrenia and lung cancer patients", 67, pp.71~4 (2004)
91. "may be associated with tardive dyskinesia but not with the development of schizophrenia", qui(ne oxidoreductase), pp.495~500
92. "Association between polymorphism in intron 1 of cocaine- and amphetamine-regulated transcript gene with alcoholism,but not with bipolar disorder and schizophrenia in Korean population", 365, pp.54~7 (2004)
93. "BanI polymorphism of the cytosolic phospholipase A2 gene may confer susceptibility to the development of schizophrenia", 28, pp.739~41 (2004)
94. "Epidermal growth factor gene polymorphism is different between schizophrenia and lung cancer patients in Korean population", 374, pp.157~60 (2005)
95. "A comparative proteome analysis of hippocampal tissue from schizophrenic and Alzheimer's disease individuals", 4, pp.173~8 (1999)
96. "Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia", 98, pp.4746~51 (2001)
97. "Dimensions of psychosis in affected sibling pairs", 25, pp.841~50 (1999)
98. "Genetic heterogeneity in schizophrenia:stratification of genome scan data using co-segregating related phenotypes", 5, pp.650~3 (2000)
99. "Genetic heterogeneity in schizophrenia:stratification of genome scan data using co-segregating related phenotypes", 5, pp.650~3 (2000)

관련 논문AI추천