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노인 입원 환자에서 섬망 발생과 결과에 대한 후향적 연구

Retrospective Study on the Development and Outcome of Delirium in Elderly Inpatient

이재민|김정란|김재헌|차승민|임채성
대한생물치료정신의학회 (Korean Society Of Biological Therapies In Psychiatry)|2012.10|생물치료정신의학 (Journal of the Korean Society of Biological Therapies in Psychiatry)|제18권 제2호|pp. 186-193

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참고문헌

키워드

노인결과ElderlyOutcome섬망Delirium후향적 연구Retrospective
주제분류정신과학

초록

Objectives：This study was aimed to examine the development and outcome of delirium in elderly inpatients retrospectively. Methods：We reviewed medical records of 2,570 patients, who were referred to consultation of psychiatry between January 2007 and December 2011. We found 916 patients(35.6%) who were confirmed as delirium by psychiatrists with DSM-IV-TR diagnostic criteria. The epidemiologic and clinical information were obtained and the factors affecting on recovery and recurrence of delirium were explored. All statistical analyses were conducted by using Pearson Chi-Square test, Student`s t-test, Binary logistic regression analysis with SPSS 17.0. Results：916 patients presented delirium. 577 patients(63.0%) were men and 339 patients(37.0%) were women. The mean of age was 74.6 years. The most frequently prescribed medicine was risperidone(52.7%), and followed by quetiapine(26.8%), olanzapine (9.9%). We found significant differences in Sex, Age, Ambulation state and Treatment in recovered and unchanged patients group. Additionally we also found that male sex can be a risk factor of recurrent delirium(OR 1.914, CI 1.102-3.323). Conclusion：These results suggest that female, advanced age, ambulation and antipsychotic medication can be associated with positive outcome of delirium, whereas male can increase the risk of recurrence of delirium.

Abstract

Objectives：This study was aimed to examine the development and outcome of delirium in elderly inpatients retrospectively. Methods：We reviewed medical records of 2,570 patients, who were referred to consultation of psychiatry between January 2007 and December 2011. We found 916 patients(35.6%) who were confirmed as delirium by psychiatrists with DSM-IV-TR diagnostic criteria. The epidemiologic and clinical information were obtained and the factors affecting on recovery and recurrence of delirium were explored. All statistical analyses were conducted by using Pearson Chi-Square test, Student`s t-test, Binary logistic regression analysis with SPSS 17.0. Results：916 patients presented delirium. 577 patients(63.0%) were men and 339 patients(37.0%) were women. The mean of age was 74.6 years. The most frequently prescribed medicine was risperidone(52.7%), and followed by quetiapine(26.8%), olanzapine (9.9%). We found significant differences in Sex, Age, Ambulation state and Treatment in recovered and unchanged patients group. Additionally we also found that male sex can be a risk factor of recurrent delirium(OR 1.914, CI 1.102-3.323). Conclusion：These results suggest that female, advanced age, ambulation and antipsychotic medication can be associated with positive outcome of delirium, whereas male can increase the risk of recurrence of delirium.

참고문헌 (27)

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