약물치료를 받는 우울증 환자에서 자살성 예측인자
Predictors of Suicidality in Depressive Patients Receiving Pharmacotherapy
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Objectives：This study investigated factors related to increased suicidal severity and fatal/nonfatal suicide attempt in depressive patients receiving pharmacotherapy. Methods：This study included 1246 participants who received one year pharmacological treatment for depressive disorders. Socio-demographic and clinical variables were collected. The following scales were used : Brief Psychiatric Rating Scale (BPRS), Hospital Anxiety and Depression Scale (HADS), EuroQol-5D (EQ-5D), Social and Occupational Functional Assessment Scale (SOFAS), Life Experiences Survey (LES), Perceived Stress Scale (PSS), Korean version of Connor-Davidson Resilience Scale (K-CD-RISC), Multidimensional Scale of Perceived Social Support (MSPSS) and Alcohol Use Disorder Identification Test (AUDIT). Up to one year follow-up period, suicidality which are increased suicidal severity and fatal/nonfatal suicide attempt were followed. Logistic regression analyses were used to identify predictors for increased suicidal severity and fatal/nonfatal suicide attempt. Results：Of the 1,246 participants, 222(18%) reported increased suicidal severity and 45(3.6%) showed fatal/non- fatal suicide attempt. Increased suicidal severity were more independently associated with unemployment (OR=1.49, p=0.01), increased treatment step (OR=1.26, p<0.01), and fatal/non-fatal suicide attempt were independently associ ated with number of depressive episodes (OR=1.24, p=0.01), HADS-D (OR=1.11, p=0.02), AUDIT-K (OR=1.03, p= 0.03), increased treatment step (OR=1.24, p=0.02). Conclusions：Not only social and economic support system but also depression treatment might aid suicide pre vention. The results of this study are expected to be useful in considering risk factors related to suicide prevention in outpatient care in the future.
Abstract
Objectives：This study investigated factors related to increased suicidal severity and fatal/nonfatal suicide attempt in depressive patients receiving pharmacotherapy. Methods：This study included 1246 participants who received one year pharmacological treatment for depressive disorders. Socio-demographic and clinical variables were collected. The following scales were used : Brief Psychiatric Rating Scale (BPRS), Hospital Anxiety and Depression Scale (HADS), EuroQol-5D (EQ-5D), Social and Occupational Functional Assessment Scale (SOFAS), Life Experiences Survey (LES), Perceived Stress Scale (PSS), Korean version of Connor-Davidson Resilience Scale (K-CD-RISC), Multidimensional Scale of Perceived Social Support (MSPSS) and Alcohol Use Disorder Identification Test (AUDIT). Up to one year follow-up period, suicidality which are increased suicidal severity and fatal/nonfatal suicide attempt were followed. Logistic regression analyses were used to identify predictors for increased suicidal severity and fatal/nonfatal suicide attempt. Results：Of the 1,246 participants, 222(18%) reported increased suicidal severity and 45(3.6%) showed fatal/non- fatal suicide attempt. Increased suicidal severity were more independently associated with unemployment (OR=1.49, p=0.01), increased treatment step (OR=1.26, p<0.01), and fatal/non-fatal suicide attempt were independently associ ated with number of depressive episodes (OR=1.24, p=0.01), HADS-D (OR=1.11, p=0.02), AUDIT-K (OR=1.03, p= 0.03), increased treatment step (OR=1.24, p=0.02). Conclusions：Not only social and economic support system but also depression treatment might aid suicide pre vention. The results of this study are expected to be useful in considering risk factors related to suicide prevention in outpatient care in the future.
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