본문 바로가기
KERD
논문KCI 등재

농촌지역 우울증 고위험군에서 만성 의학적 질환과 우울증상 : 1년 추적관찰 연구

Chronic Medical Diseases and Depressive Symptoms in a Rural Group at High Risk for Depression : A 1-Year Follow-Up Study

이철순|서지영|이동윤|박철수|강경희|이선숙|김봉조|이소진|이영지|최재원|차보석|정병선|오희옥
대한생물치료정신의학회 (Korean Society Of Biological Therapies In Psychiatry)|2019.10|생물치료정신의학 (Journal of the Korean Society of Biological Therapies in Psychiatry)|제25권 제3호|pp. 222-231|DOI 10.22802/jksbtp.2019.25.3.222

2

조회

0

다운로드

0

인용

0

참고문헌

키워드

만성 의학적 질환·우울증·농촌주민·당뇨Chronic medical diseases · Depression · Rural population · Diabetes mellitus
주제분류정신과학

초록

Objectives：This study investigated the effects of chronic medical diseases on depressive symptoms in individuals at high risk for depression living in rural areas, over a 1-year period. Methods：A community-based longitudinal study was conducted; 67 participants aged 18-79 years residing in rural areas were included. In the first survey, all participants completed a self-report questionnaire battery. An interview was also conducted to obtain data on demographic variables and current or past chronic medical diseases. In the first survey, participants with the Center for Epidemiologic Studies Depression scale(CES-D) scores of 16 or higher were categorized as being at high risk for depression; the same assessments were carried out 1 year later in a follow-up survey. Multiple regression analysis was performed to determine the association of chronic medical diseases with 1-year follow-up depressive symptoms in the high-risk group. Results：In model 1, which controlled for sociodemographic variables, the number of chronic medical diseases ( p =0.026), baseline severity of depressive symptoms( p =0.002), and presence of diabetes( p =0.039) were significantly associated with the follow-up CES-D scores. In model 2, which further adjusted for Alcohol Use Disorder Identification Test and Beck Anxiety Inventory scores, the number of chronic medical diseases( p =0.036), baseline severity of depressive symptoms( p =0.017), and prevalence of diabetes( p =0.037) were also significantly associated with the follow-up CES-D scores. Conclusion：This study suggests that the number of chronic medical diseases, prevalence of diabetes, and severity of depressive symptoms are significantly associated with 1-year follow-up depressive symptoms in individuals at high risk for depression.

Abstract

Objectives：This study investigated the effects of chronic medical diseases on depressive symptoms in individuals at high risk for depression living in rural areas, over a 1-year period. Methods：A community-based longitudinal study was conducted; 67 participants aged 18-79 years residing in rural areas were included. In the first survey, all participants completed a self-report questionnaire battery. An interview was also conducted to obtain data on demographic variables and current or past chronic medical diseases. In the first survey, participants with the Center for Epidemiologic Studies Depression scale(CES-D) scores of 16 or higher were categorized as being at high risk for depression; the same assessments were carried out 1 year later in a follow-up survey. Multiple regression analysis was performed to determine the association of chronic medical diseases with 1-year follow-up depressive symptoms in the high-risk group. Results：In model 1, which controlled for sociodemographic variables, the number of chronic medical diseases ( p =0.026), baseline severity of depressive symptoms( p =0.002), and presence of diabetes( p =0.039) were significantly associated with the follow-up CES-D scores. In model 2, which further adjusted for Alcohol Use Disorder Identification Test and Beck Anxiety Inventory scores, the number of chronic medical diseases( p =0.036), baseline severity of depressive symptoms( p =0.017), and prevalence of diabetes( p =0.037) were also significantly associated with the follow-up CES-D scores. Conclusion：This study suggests that the number of chronic medical diseases, prevalence of diabetes, and severity of depressive symptoms are significantly associated with 1-year follow-up depressive symptoms in individuals at high risk for depression.

참고문헌 (48)

  1. Hawton K, "Risk factors for suicide in individuals with depression : a systematic review", J Affective Disord, 147, pp.17~28 (2013)
  2. 오동훈, "Prevalence and Correlates of Depressive Symptoms in Korean Adults : Results of a 2009 Korean Community Health Survey", Journal of Korean Medical Science, 28(1), pp.128~135 (2013), 대한의학회
  3. 전홍진, "우울증과 자살 역학연구", 대한의사협회지, 55(4), pp.322~328 (2012), 대한의사협회[DOI]
  4. Burcusa SL, "Risk for recurrence in depression", Clin Psychol Rev, 27, pp.959~985 (2007)
  5. Spijker J, "Duration of major depressive episodes in the general population : results from The netherlands mental health survey and incidence study(NEMESIS)", Br J Psychiatry, 181, pp.208~213 (2002)
  6. Miller IW, "The treatment of chronic depression, part 3: psychosocial functioning before and after treatment with sertraline or imipramine", J Clin Psychiatry, 59, pp.608~619 (1998)
  7. Howland RH, "Chronic depression", Hosp Community Psychiatry, 44, pp.633~639 (1993)
  8. Klein DN, "Thirty-month naturalistic follow-up study of early-onset dysthymic disorder: course, diagnostic stability, and prediction of outcome", J Abnorm Psychol, 107, pp.338~348 (1998)
  9. Devanand D, "Late onset dysthymic disorder and major depression differ from early onset dysthymic disorder and major depression in elderly outpatients", J Affect Disord, 78, pp.259~267 (2004)
  10. Nakanishi T, "Chronic depression of monopolar, endogenous type: with special reference to the premorbid personality, “Typus melancholicus”", Jpn J Psychiatry Neurol, 47, pp.495~504 (1993)
  11. Melartin TK, "Severity and comorbidity predict episode duration and recurrence of DSM-IV major depressive disorder", J Clin Psychiatry, 65, pp.810~819 (2004)
  12. Klein DN, "Primary early-onset dysthymia: comparison with primary nonbipolar nonchronic major depression on demographic, clinical, familial, personality, and socioenvironmental characteristics and short-term outcome", J Abnorm Psychol, 97, pp.387~398 (1988)
  13. Baune BT, "Associations between major depression, bipolar disorders, dysthymia and cardiovascular diseases in the general adult population", Psychother Psychosom, 75, pp.319~326 (2006)
  14. Harpole LH, "Improving depression outcomes in older adults with comorbid medical illness", Gen Hosp Psychiatry, 27, pp.4~12 (2005)
  15. Katon WJ., "Clinical and health services relationships between major depression, depressive symptoms, and general medical illness", Biol Psychiatry, 54, pp.216~226 (2003)
  16. Nouwen A, "Type 2 diabetes mellitus as a risk factor for the onset of depression : a systematic review and meta-analysis", Diabetologia, 53, pp.2480~2486 (2010)
  17. Batal O, "Sleep quality, depression, and quality of life in patients with pulmonary hypertension", Lung, 189, pp.141~149 (2011)
  18. Egede LE., "Major depression in individuals with chronic medical disorders: prevalence, correlates and association with health resource utilization, lost productivity and functional disability", Gen Hosp Psychiatry, 29, pp.409~416 (2007)
  19. Sweileh WM, "Prevalence of depression among people with type 2 diabetes mellitus : a cross sectional study in Palestine", BMC Public Health, 14, pp.163~ (2014)
  20. Polsky D, "Long-term risk for depressive symptoms after a medical diagnosis", Arch Intern Med, 165, pp.1260~1266 (2005)
  21. Laurin C, "Impact of anxiety and depression on chronic obstructive pulmonary disease exacerbation risk", Am J Respir Crit Care Med, 185, pp.918~923 (2012)
  22. 장지훈, "농촌지역 주민들에서 만성 의학적 질환이 자살사고에 미치는 영향 : 성인과 노인의 차이", 생물치료정신의학, 22(3), pp.137~145 (2016), 대한생물치료정신의학회
  23. Radloff LS, "The use of the center for epidemiologic studies depression scale in adolescents and young adults", J Youth Adolesc, 20, pp.149~166 (1991)
  24. Cho MJ, "Use of the center for epidemiologic studies depression(CES-D)scale in Korea", J Nerv Ment Dis, 186, pp.304~310 (1998)
  25. Radloff L, "The CES-D scale : A self-report depression scale for research in the general population", Appl Psych Meas, 1, pp.385~401 (1977)
  26. Beck AT, "Assessment of suicidal intention : the scale for suicide ideation", J Consult Clin Psychol, 47, pp.343~352 (1979)
  27. Shin MS, "A study of suicidal ideation among high school students: the structural relation among depression, hopelessness, and suicidal ideation", Korean J Clin Psychol, 9, pp.1~19 (1990)
  28. Beck AT, "An inventory for measuring clinical anxiety : psychometric properties", J Consult Clin Psychol, 56, pp.893~897 (1988)
  29. Yook SP, "A clinical study on the Korean version of Beck Anxiety Inventory : comparative study of patient and non-patient", Korean J Clin Psychol, 16, pp.185~197 (1997)
  30. Lee BO, "Development of Korean version of alcohol use disorders identification test(AUDIT-K) : Its reliability and validity", J Korean Acad Addict Psychiatry, 4, pp.83~92 (2000)
  31. Murphy KR, "Statistical power analysis: A simple and general model for traditional and modern hypothesis tests" (2014), Routledge
  32. Faravelli C, "Depressive relapses and incomplete recovery from index episode", Am J Psychiatry, 143, pp.888~891 (1986)
  33. Kim JM, "Predictors of 12-week remission in a nationwide cohort of people with depressive disorders : the CRESCEND study", Hum Psychopharmacol, 26, pp.41~50 (2011)
  34. Greden JF., "The burden of recurrent depression: causes, consequences, and future prospects", J Clin Psychiatry, 62, pp.5~9 (2001)
  35. de Groot M, "Lifetime duration of depressive disorders in patients with type 2 diabetes", Diabetes Care, 39, pp.2174~2181 (2016)
  36. Stumetz KS, "Quality of care in rural youth with type 1 diabetes: a crosssectional pilot assessment", BMJ Open Diabetes Res Care, 4, pp.e000300~ (2016)
  37. Dorsey AM. Rural healthy people 2010: a companion document to healthy people 2010, "Gamm LD", The Texas A&M University system health science center, school of rural public health, southwest rural health research center, ~ (2003)
  38. van Dooren FE, "Depression and risk of mortality in people with diabetes mellitus: a systematic review and meta-analysis", PLoS One, 8, pp.e57058~ (2013)
  39. Samaan Z, "Lack of association between type 2 diabetes and major depression: epidemiologic and genetic evidence in a multiethnic population", Transl Psychiatry, 5, pp.e618~ (2015)
  40. Kyrou I, "Stress hormones : physiological stress and regulation of metabolism", Curr Opin Pharmacol, 9, pp.787~793 (2009)
  41. Chrousos GP, "Stress and disorders of the stress system", Nat Rev Endocrinol, 5, pp.374~381 (2009)
  42. Tabák AG, "Depression and type 2 diabetes : a causal association?", Lancet Diabetes Endocrinol, 2, pp.236~245 (2014)
  43. Moulton CD, "The link between depression and diabetes : the search for shared mechanisms", Lancet Diabetes Endocrinol, 3, pp.461~471 (2015)
  44. Linden W, "Anxiety and depression after cancer diagnosis: prevalence rates by cancer type, gender, and age", J Affect Disord, 141, pp.343~351 (2012)
  45. Cohen BE, "State of the art review: depression, stress, anxiety, and cardiovascular disease", Am J Hypertens, 28, pp.1295~1302 (2015)
  46. Ramana R, "Remission and relapse in major depression : a two-year prospective follow-up study", Psychol Med, 25, pp.1161~1170 (1995)
  47. Keller MB, "Implications of failing to achieve successful long-term maintenance treatment of recurrent unipolar major depression", Biol Psychiatry, 44, pp.348~360 (1998)
  48. Sherrington JM, "Outcome of women admitted to hospital for depressive illness : factors in the prognosis of severe depression", Psychol Med, 31, pp.115~125 (2001)

관련 논문AI추천

농촌지역 주민들에서 만성 의학적 질환이 자살사고에 미치는 영향 : 성인과 노인의 차이김봉조, 박철수, 서지영, 안인영, 이동윤, 이소진, 이철순, 장지훈, 차보석, 최재원대한생물치료정신의학회 · 생물치료정신의학2016 · 제22권 제3호농촌지역 독거노인의 사회적 지지 및 만성 의학적 질환이 우울증상에 미치는 영향김봉조, 박철수, 서지영, 안인영, 이동윤, 이상수, 이소진, 이철순, 차보석, 채철호, 최재원대한생물치료정신의학회 · 생물치료정신의학2018 · 제24권 제3호경남 지역 농촌 여성들의 우울 증상과 관련된 위험 요인김봉조, 김선미, 김지훈, 박기수, 박철수, 이소진, 이진향, 이철순, 전진호, 차보석대한생물치료정신의학회 · 생물치료정신의학2012 · 제18권 제2호우울증과 신체 질환과의 연관성 및 위험요인: 대규모 국내 역학 연구 자료분석김병수, 박현규, 이지민, 장성만대한생물치료정신의학회 · 생물치료정신의학2022 · 제28권 제3호성인의 만성질환 유형에 따른 우울변화에 영향을 미치는 요인에 관한 연구김윤화, 손태용보건의료산업학회 · 보건의료산업학회지2017 · 제11권 제4호The Prevalence of Chronic Physical Diseases Comorbid with Depression among Different Sex and Age Groups in South Korea: A Population-Based Study, 2007–2014박수빈, Boram Yuk, Chul Eung Kim, Hyesue Jang, Jung Won Jang, Se Jin Park, Seungyeon Hong대한신경정신의학회 · PSYCHIATRY INVESTIGATION2018 · 제15권 제4호

이 간행물의 다른 논문 (8건)

정신장애의 진화적 가설 및 한계박한선pp. 165-182대마의 정신의학적 영향김병수pp. 183-191학습과 옥시토신정영인, 이병대, 이영민pp. 192-204지역사회 거주 노인에서 자살 사고의 관련 인자김재민, 윤진상, 신희영, 김성완, 신일선, 윤호석pp. 205-212고혈압 환자에서 우울증상의 유병률과 심리사회적 관련 요인김상훈, 윤형준, 김승곤, 전다정, 김정호, 박상학pp. 213-221
원문 보기