Impact of Sulphurous Water Politzer Inhalation on Audiometric Parameters in Children with Otitis Media with Effusion
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Objectives. The positive effects of spa therapy on ear, nose, and throat pathology are known but robust literature in this field, is still lacking. The aim of this study was to assess through a retrospective analysis, the effects on otitis media with effusion of Politzer endotympanic inhalation of sulphurous waters in children aged 5-9 years. Methods. A cohort of 95 patients was treated with Politzer insufflations of sulphurous water: 58 patients did a cycle consisting of a treatment of 12 days per year for three consecutive years; 37 patients followed the same procedure for 5 years consecutively. The control population was represented by untreated, age-matched children. A standard audiometric test was used before and after each cycle of treatment. Results. One cycle of Politzer inhalation of sulphur-rich water improved the symptoms. Three cycles definitively stabilized the improvement of hearing function. Conclusion. Our results show that otitis media with effusion in children can be resolved by an appropriate non-pharmacological treatment of middle ear with sulphur-rich water.
Abstract
Objectives. The positive effects of spa therapy on ear, nose, and throat pathology are known but robust literature in this field, is still lacking. The aim of this study was to assess through a retrospective analysis, the effects on otitis media with effusion of Politzer endotympanic inhalation of sulphurous waters in children aged 5-9 years. Methods. A cohort of 95 patients was treated with Politzer insufflations of sulphurous water: 58 patients did a cycle consisting of a treatment of 12 days per year for three consecutive years; 37 patients followed the same procedure for 5 years consecutively. The control population was represented by untreated, age-matched children. A standard audiometric test was used before and after each cycle of treatment. Results. One cycle of Politzer inhalation of sulphur-rich water improved the symptoms. Three cycles definitively stabilized the improvement of hearing function. Conclusion. Our results show that otitis media with effusion in children can be resolved by an appropriate non-pharmacological treatment of middle ear with sulphur-rich water.
참고문헌 (16)
- Rinaldi L, "Hydrogen sulfide prevents apoptosis of human PMN via inhibition of p38 and caspase 3", Lab Invest, 86(4), pp.391~397 (2006)
- Gobbi G, "Hydrogen sulfide impairs keratinocyte cell growth and adhesion inhibiting mitogen-activated protein kinase signaling", Lab Invest, 89(9), pp.994~1006 (2009)
- Mirandola P, "Exogenous hydrogen sulfide induces functional inhibition and cell death of cytotoxic lymphocytes subsets", J Cell Physiol, 213(3), pp.826~833 (2007)
- Vaccarezza M, "Thermal spa therapy: a neglected resource for human health now re-emerging on sound scientific concepts", Int J Biometeorol, 54(5), pp.491~493 (2010)
- Franchimont P, "Hydrotherapy: mechanisms and indications", Pharmacol Ther, 20(1), pp.79~93 (1983)
- Petraccia L, "Water, mineral waters and health", Clin Nutr, 25(3), pp.377~385 (2006)
- Costantino M, "The rhinogenic deafness and SPA therapy: clinical-experimental study", Clin Ter, 159(5), pp.311~315 (2008)
- Olina M, "Hydrological indications in the therapy of pharyngitis", Recenti Prog Med, 99(6), pp.314~321 (2008)
- Costantino M, "Effectiveness of sulphur spa therapy with politzer in the treatment of rhinogenic deafness", Acta Otorhinolaryngol Ital, 26(1), pp.7~13 (2006)
- Salami A, "Sulphurous water inhalations in the prophylaxis of recurrent upper respiratory tract infections", Int J Pediatr Otorhinolaryngol, 72(11), pp.1717~1722 (2008)
- Szabo C, "Hydrogen sulphide and its therapeutic potential", Nat Rev Drug Discov, 6(11), pp.917~935 (2007)
- Yang G, "H2S as a physiologic vasorelaxant: hypertension in mice with deletion of cystathionine gamma-lyase", Science, 322(5901), pp.587~590 (2008)
- Caliendo G, "Synthesis and biological effects of hydrogen sulfide (H2S): development of H2S-releasing drugs as pharmaceuticals", J Med Chem, 53(17), pp.6275~6286 (2010)
- Bluestone CD, "Otitis media and sinusitis: management and when to refer to the otolaryngologist", Pediatr Infect Dis J, 6(1), pp.100~106 (1987)
- Bylander A, "Upper respiratory tract infection and Eustachian tube function in children", Acta Otolaryngol, 97(3-4), pp.343~349 (1984)
- Falagas ME, "The therapeutic effect of balneotherapy: evaluation of the evidence from randomised controlled trials", Int J Clin Pract, 63(7), pp.1068~1084 (2009)