Nasopharynx as a Microbiologic Reservoir in Chronic Suppurative Otitis Media: Preliminary Study
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Objectives. The present study was designed to identify the correlations of bacterial strains of the middle ear and the nasopharynx in chronic suppurative otitis media (CSOM) patients who were scheduled for operations. Methods. Sixty-three patients with CSOM were enrolled in the study. Culture specimens were collected from the middle ear and nasopharynx of patients who were admitted for operation. Samples collections were performed 3 times;from the middle ear and nasophaynx at the admission day, from the middle ear during the operation, and from the external auditory canal post-operatively. Bacteria were identified by gram staining and biochemical tests. The correspondence rate of organisms which simultaneously exist in the middle ear and the nasopharynx was measured. Results. Sixty-eight organisms were isolated from the middle ear and 57 organisms from the nasopharynx among 63 patients. Of 68 bacteria identified in middle ear, 26.52% (18 bacteria) corresponded with those of nasopharynx. MRSA had the high correspondence rate, and of 18 methicillin-resistant Staphylococcus aureus (MRSA) isolated from middle ear, 33.3% (6 bacteria) corresponded with nasophaynx. Meanwhile, 3 organisms of MRSA were detected from the external auditory canal post-operatively, although they were only found in nasopharynx pre-operatively. Conclusion. The current trend of middle ear swab alone for bacterial detection would be insufficient to identify the potent MRSA and impede early antibiotic intervention for the effective middle ear surgery. Therefore, it is necessary to perform nasopharynx cultures together with conventional middle ear culture to control potent risk for infection pre-operatively.
Abstract
Objectives. The present study was designed to identify the correlations of bacterial strains of the middle ear and the nasopharynx in chronic suppurative otitis media (CSOM) patients who were scheduled for operations. Methods. Sixty-three patients with CSOM were enrolled in the study. Culture specimens were collected from the middle ear and nasopharynx of patients who were admitted for operation. Samples collections were performed 3 times;from the middle ear and nasophaynx at the admission day, from the middle ear during the operation, and from the external auditory canal post-operatively. Bacteria were identified by gram staining and biochemical tests. The correspondence rate of organisms which simultaneously exist in the middle ear and the nasopharynx was measured. Results. Sixty-eight organisms were isolated from the middle ear and 57 organisms from the nasopharynx among 63 patients. Of 68 bacteria identified in middle ear, 26.52% (18 bacteria) corresponded with those of nasopharynx. MRSA had the high correspondence rate, and of 18 methicillin-resistant Staphylococcus aureus (MRSA) isolated from middle ear, 33.3% (6 bacteria) corresponded with nasophaynx. Meanwhile, 3 organisms of MRSA were detected from the external auditory canal post-operatively, although they were only found in nasopharynx pre-operatively. Conclusion. The current trend of middle ear swab alone for bacterial detection would be insufficient to identify the potent MRSA and impede early antibiotic intervention for the effective middle ear surgery. Therefore, it is necessary to perform nasopharynx cultures together with conventional middle ear culture to control potent risk for infection pre-operatively.
참고문헌 (17)
- Albert RR, "Outcome of bacterial culture from mastoid granulations: is it relevant in chronic ear disease", J Laryngol Otol, 119(10), pp.774~778 (2005)
- Stroman DW, "Microbiology of normal external auditory canal", Laryngoscope, 111(11 Pt 1), pp.2054~2059 (2001)
- Yeo SG, "Bacteriology of chronic suppurative otitis media: a multicenter study", Acta Otolaryngol, 127(10), pp.1062~1067 (2007)
- Schwartz R, "The nasopharyngeal culture in acute otitis media: a reappraisal of its usefulness", JAMA, 241(20), pp.2170~2173 (1979)
- Kamme C, "The aetiology of acute otitis media in children. Occurrence of bacteria, L forms of bacteria and mycoplasma in the middle ear exudate. Relationship between bacterial findings in the middle ear exudate, nasopharynx and throat", Scand J Infect Dis, 3(3), pp.217~223 (1971)
- Syrjanen RK, "The value of nasopharyngeal culture in predicting the etiology of acute otitis media in children less than two years of age", Pediatr Infect Dis J, 25(11), pp.1032~1036 (2006)
- Harker LA, "Complication of temporal bone infections, In Otolaryngology: head & neck surgery. 4th ed", pp.3013~3039 (2004), Elsevier Mosby
- Koh EK, "The bacteriology of cholesteatoma, In Cholesteatoma", pp.49~63 (1996), Chung-Ang Publishing
- Lee KS, "A study of ofloxacin ear drops versus amoxicillin", clavulanic acid in the treatment of chronic suppurative otitis media, 1998, pp.2(2), 181~189
- Erkan M, "Bacteriology of chronic suppurative otitis media", Ann Otol Rhinol Laryngol, 103(10), pp.771~774 (1994)
- Jevons MP, "Celbenin: resistant Staphylococci", Br Med J, 1(5219), pp.124~125 (1961)
- Lowy FD, "Staphylococcus aureus infections", N Engl J Med, 339(8), pp.520~532 (1998)
- Kim WJ, "Result and surgical consideration for chronic suppurative otitis media with methicillin-resistant Staphylococcus aureus", Korean J Audiol, 13(3), pp.222~225 (2009)
- Palva T, "Bacteriology of chronic otitis media: results of analyses from the ear canal and from the operative cavity", Arch Otolaryngol, 82(4), pp.359~364 (1965)
- Harputluoglu U, "Nasopharyngeal aerobic bacterial flora and Staphylococcus aureus nasal carriage in deaf children", Int J Pediatr Otorhinolaryngol, 69(1), pp.69~74 (2005)
- Creech CB 2nd, "Increasing rates of nasal carriage of methicillin-resistant Staphylococcus aureus in healthy children", Pediatr Infect Dis J, 24(7), pp.617~621 (2005)
- Crum NF, "Fifteen-year study of the changing epidemiology of methicillin-resistant Staphylococcus aureus", Am J Med, 119(11), pp.943~951 (2006)