Is Hypozincemia Related to Tinnitus?: A Population Study Using Data From the Korea National Health and Nutrition Examination Survey
2
조회
0
다운로드
1
인용
0
참고문헌
키워드
초록
Objectives. The aim of present study was to determine the relationship between serum zinc level and tinnitus using data from the Korea National Health and Nutrition Examination Survey (KNHANES). Methods. The present study examined the relationship between serum zinc level and tinnitus using data from the KNHANES. A total of 2,225 KNHANES participants responded to the tinnitus questionnaire and provided blood samples to measure serum zinc concentration. Based on questionnaire responses, participants were categorized into control, mild tinnitus, moderate tinnitus, and severe tinnitus subgroups. Results. There were no significant differences between groups in serum zinc level after adjustment for sex, age, and hearing loss. Conclusion. It was concluded that hypozincemia is not related to tinnitus in a large population.
Abstract
Objectives. The aim of present study was to determine the relationship between serum zinc level and tinnitus using data from the Korea National Health and Nutrition Examination Survey (KNHANES). Methods. The present study examined the relationship between serum zinc level and tinnitus using data from the KNHANES. A total of 2,225 KNHANES participants responded to the tinnitus questionnaire and provided blood samples to measure serum zinc concentration. Based on questionnaire responses, participants were categorized into control, mild tinnitus, moderate tinnitus, and severe tinnitus subgroups. Results. There were no significant differences between groups in serum zinc level after adjustment for sex, age, and hearing loss. Conclusion. It was concluded that hypozincemia is not related to tinnitus in a large population.
참고문헌 (24)
- Moller AR, "Tinnitus: presence and future", Prog Brain Res, 166, pp.3~16 (2007)
- Patterson MB, "Review of pharmacological therapy for tinnitus", Int Tinnitus J, 12(2), pp.149~159 (2006)
- Salvi R, "Pharmacological treatments for tinnitus: new and old", Drugs Future, 34(5), pp.381~400 (2009)
- Zirpel L, "Zinc inhibition of group I mGluR-mediated calcium homeostasis in auditory neurons", J Assoc Res Otolaryngol, 2(2), pp.180~187 (2001)
- Rarey KE, "Localization of Cu", Zn-SOD and Mn-SOD in the rat cochlea, 1996, pp.116(6), 833~835
- Speich M, "trace elements and related biological variables in athletes and during physical activity", Clin Chim Acta, 312(1-2), pp.1~11 (2001)
- McFadden SL, "Cu", Zn SOD deficiency potentiates hearing loss and cochlear pathology in aged 129,CD-1 mice, 1999, pp.413(1), 101~112
- Arda HN, "role of zinc in the treatment of tinnitus", Otol Neurotol, 24(1), pp.86~89 (2003)
- Ochi K, "The serum zinc level in patients with tinnitus and the effect of zinc treatment", Nihon Jibiinkoka Gakkai Kaiho, 100(9), pp.915~919 (1997)
- Shambaugh GE Jr, "Zinc and presbycusis", Am J Otol, 6(1), pp.116~117 (1985)
- Yetiser S, "The role of zinc in management of tinnitus", Auris Nasus Larynx, 29(4), pp.329~333 (2002)
- Paaske PB, "Zinc in the management of tinnitus. Placebo-controlled trial", Ann Otol Rhinol Laryngol, 100(8), pp.647~649 (1991)
- Coelho C, "Zinc to treat tinnitus in the elderly: a randomized placebo controlled crossover trial", Otol Neurotol, 34(6), pp.1146~1154 (2013)
- Gersdorff M, "A clinical correlation between hypozincemia and tinnitus", Arch Otorhinolaryngol, 244(3), pp.190~193 (1987)
- Hotz C, "Suggested lower cutoffs of serum zinc concentrations for assessing zinc status: reanalysis of the second National Health and Nutrition Examination Survey data (1976-1980)", Am J Clin Nutr, 78(4), pp.756~764 (2003)
- Gibson RS, "Principles of nutritional assessment" (2005), Oxford University Press
- Chung DY, "Factors affecting the prevalence of tinnitus", Audiology, 23(5), pp.441~452 (1984)
- Hoffman HJ, "Tinnitus: theory and management", pp.16~41 (2004), BC Decker
- Hazell J, "Tinnitus and disability with ageing: adaptation and management", Acta Otolaryngol (Stockh), 111(Suppl 476), pp.202~208 (1991)
- Nondahl DM, "Tweed TS. Prevalence and 5-year incidence of tinnitus among older adults: the epidemiology of hearing loss study", J Am Acad Audiol, 13(6), pp.323~331 (2002)
- Sindhusake D, "Risk factors for tinnitus in a population of older adults: the blue mountains hearing study", Ear Hear, 24(6), pp.501~507 (2003)
- Shambaugh GE Jr, "Zinc for tinnitus, imbalance, and hearing loss in the elderly", Am J Otol, 7(6), pp.476~477 (1986)
- King JC., "Assessment of zinc status", J Nutr, 120(Suppl 11), pp.1474~1479 (1990)
- Tyler R, "Identifying tinnitus subgroups with cluster analysis", Am J Audiol, 17(2), pp.s176~s184 (2008)