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Concurrent Mucosal Melanoma and Angiofibroma of the Nose

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초록

Malignant melanoma rarely develops in the paranasal sinuses, and generally has a poor prognosis. However, mucosal melanoma can masquerade both clinically and histopathologically as a benign lesion, rendering accurate early diagnosis difficult. On the other hand, angiofibroma, a benign tumor, is more easily diagnosed than a mucosal melanoma, because the former exhibits specific histopathological features. No cases of concurrent angiofibroma and mucosal melanoma have been reported to date. We describe such a case below.

Abstract

Malignant melanoma rarely develops in the paranasal sinuses, and generally has a poor prognosis. However, mucosal melanoma can masquerade both clinically and histopathologically as a benign lesion, rendering accurate early diagnosis difficult. On the other hand, angiofibroma, a benign tumor, is more easily diagnosed than a mucosal melanoma, because the former exhibits specific histopathological features. No cases of concurrent angiofibroma and mucosal melanoma have been reported to date. We describe such a case below.

참고문헌 (7)

  1. Medhi P., "Cytodiagnosis of mucosal malignant melanoma of nasal cavity : a case report with review of literature", J Cytol, 29(3), pp.208~210 (2012)
  2. Mihajlovic M., "Primary mucosal melanomas : a comprehensive review", Int J Clin Exp Pathol, 5(8), pp.739~753 (2012)
  3. Mundra RK., "Endoscopic removal of malignant melanoma of the nasal cavity", Indian J Otolaryngol Head Neck Surg, 57(4), pp.341~343 (2005)
  4. Rinaldo A., "Primary mucosal melanoma of the nasal cavity and paranasal sinuses", Acta Otolaryngol, 121(8), pp.979~982 (2001)
  5. Mendenhall WM., "Head and neck mucosal melanoma", Am J Clin Oncol, 28(6), pp.626~630 (2005)
  6. Grant-Kels JM., "The misdiagnosis of malignant melanoma", J Am Acad Dermatol, 40(4), pp.539~548 (1999)
  7. Clifton N., "Malignant melanoma of nasal cavity and paranasal sinuses : report of 24 patients and literature review", J Laryngol Otol, 125(5), pp.479~485 (2011)

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