Samter’s Triad: State of the Art
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Samter’s triad (ST) is a well-known disease characterized by the triad of bronchial asthma, nasal polyps, and aspirin intolerance. Over the past few years, a rapid development in the knowledge of the pathogenesis and clinical characteristics of ST has happened. The aim of this paper is to review the recent investigations on the pathophysiological mechanisms and genetic background, diagnosis, and different therapeutic options of ST to advance our understanding of the mechanism and the therapeutic control of ST. As concern for ST increase, more application of aspirin desensitization will be required to manage this disease successfully. There is also a need for continued research efforts in pathophysiology, treatment, and possible prevention.
Abstract
Samter’s triad (ST) is a well-known disease characterized by the triad of bronchial asthma, nasal polyps, and aspirin intolerance. Over the past few years, a rapid development in the knowledge of the pathogenesis and clinical characteristics of ST has happened. The aim of this paper is to review the recent investigations on the pathophysiological mechanisms and genetic background, diagnosis, and different therapeutic options of ST to advance our understanding of the mechanism and the therapeutic control of ST. As concern for ST increase, more application of aspirin desensitization will be required to manage this disease successfully. There is also a need for continued research efforts in pathophysiology, treatment, and possible prevention.
참고문헌 (107)
- Widal F, "First complete description of the aspirin idiosyncrasy-asthma-nasal polyposis syndrome (plus urticaria): 1922 (with a note on aspirin desensitization)", J Asthma, 24(5), pp.297~300 (1987)[DOI]
- Samter M, "Intolerance to aspirin. clinical studies and consideration of its pathogenesis", Ann Intern Med, 68(5), pp.975~983 (1968)[DOI]
- Stevenson DD, "Classification of allergic and pseudoallergic reactions to drugs that inhibit cyclooxygenase enzymes", Ann Allergy Asthma Immunol, 87(3), pp.177~180 (2001)[DOI]
- Johansson SG, "Revised nomenclature for allergy for global use: report of the Nomenclature Review Committee of the World Allergy Organization, October 2003", J Allergy Clin Immunol, 113(5), pp.832~836 (2003)
- Szczeklik A, "Aspirin-induced asthma: advances in pathogenesis, diagnosis, and management", J Allergy Clin Immunol, 111(5), pp.913~921 (2003)[DOI]
- Babu KS, "Aspirin and asthma", Chest, 118(5), pp.1470~1476 (2000)[DOI]
- Szczeklik A, "Aspirin intolerance and the cyclooxygenase-leukotriene pathways", Curr Opin Pulm Med, 10(1), pp.51~56 (2004)[DOI]
- Pfaar O, "Aspirin desensitization in aspirin intolerance: update on current standards and recent improvements", Curr Opin Allergy Clin Immunol, 6(3), pp.161~166 (2006)[DOI]
- Stevenson DD, "Clinical and pathologic perspectives on aspirin sensitivity and asthma", J Allergy Clin Immunol, 118(4), pp.773~786 (2006)[DOI]
- Vally H, "The prevalence of aspirin intolerant asthma (AIA) in Australian asthmatic patients", Thorax, 57(7), pp.569~574 (2002)[DOI]
- Jenkins C, "Systematic review of prevalence of aspirin induced asthma and its implications for clinical practice", BMJ, 328(7437), pp.434~ (2004)[DOI]
- Delaney JC, "The diagnosis of aspirin idiosyncrasy by analgesic challenge", Clin Allergy, 6(2), pp.177~181 (1976)[DOI]
- Weber RW, "Incidence of bronchoconstriction due to aspirin, azo dyes, non-azo dyes, and preservatives in a population of perennial asthmatics", J Allergy Clin Immunol, 64(1), pp.32~37 (1979)[DOI]
- Dursun AB, "Predicting outcomes of oral aspirin challenges in patients with asthma, nasal polyps, and chronic sinusitis", Ann Allergy Asthma Immunol, 100(5), pp.420~425 (2008)[DOI]
- Berges-Gimeno MP, "The natural history and clinical characteristics of aspirin-exacerbated respiratory disease", Ann Allergy Asthma Immunol, 89(5), pp.474~478 (2002)[DOI]
- Szczeklik A, "Natural history of aspirin-induced asthma. AIANE investigators. European Network on Aspirin-Induced Asthma", Eur Respir J, 16(3), pp.432~436 (2000)[DOI]
- Kidon MI, "Early presentation with angioedema and urticaria in cross-reactive hypersensitivity to nonsteroidal antiinflammatory drugs among young, Asian, atopic children", Pediatrics, 116(5), pp.e675~e680 (2005)[DOI]
- Kim JE, "The prevalence of Samter's triad in patients undergoing functional endoscopic sinus surgery", Ear Nose Throat J, 86(7), pp.396~399 (2007)
- Szczeklik A, "The role of COX-1 and COX-2 in asthma pathogenesis and its significance in the use of selective inhibitors", Clin Exp Allergy, 32(3), pp.339~342 (2002)[DOI]
- Chavis C, "Lipoxins and other arachidonate derived mediators in bronchial asthma", Thorax, 55(Suppl 2), pp.S38~S41 (2000)[DOI]
- Stevenson DD, "Aspirin sensitivity and desensitization for asthma and sinusitis", Curr Allergy Asthma Rep, 9(2), pp.155~163 (2009)[DOI]
- Cowburn AS, "Overexpression of leukotriene C4 synthase in bronchial biopsies from patients with aspirin-intolerant asthma", J Clin Invest, 101(4), pp.834~846 (1998)[DOI]
- Adamjee J, "Expression of 5-lipoxygenase and cyclooxygenase pathway enzymes in nasal polyps of patients with aspirin-intolerant asthma", J Pathol, 209(3), pp.392~399 (2006)[DOI]
- Steinke JW, "Factors driving the aspirin exacerbated respiratory disease phenotype", Am J Rhinol Allergy, 29(1), pp.35~40 (2015)[DOI]
- Hamad AM, "Aspirin-induced asthma: clinical aspects, pathogenesis and management", Drugs, 64(21), pp.2417~2432 (2004)[DOI]
- Gaber F, "Increased levels of cysteinyl-leukotrienes in saliva, induced sputum, urine and blood from patients with aspirin-intolerant asthma", Thorax, 63(12), pp.1076~1082 (2008)[DOI]
- Capra V, "Molecular and functional aspects of human cysteinyl leukotriene receptors", Pharmacol Res, 50(1), pp.1~11 (2004)[DOI]
- Hui Y, "Cysteinyl leukotriene receptors", Biochem Pharmacol, 64(11), pp.1549~1557 (2002)[DOI]
- Jenneck C, "Pathogenesis, diagnosis, and treatment of aspirin intolerance", Ann Allergy Asthma Immunol, 99(1), pp.13~21 (2007)[DOI]
- Sousa AR, "Leukotriene-receptor expression on nasal mucosal inflammatory cells in aspirin-sensitive rhinosinusitis", N Engl J Med, 347(19), pp.1493~1499 (2002)[DOI]
- Kim SH, "CysLTR1 promoter polymorphism and requirement for leukotriene receptor antagonist in aspirin-intolerant asthma patients", Pharmacogenomics, 8(9), pp.1143~1150 (2007)[DOI]
- Peters-Golden M, "Leukotrienes", N Engl J Med, 357(18), pp.1841~1854 (2007)[DOI]
- Szczeklik A, "Prostaglandin E2 and aspirin-induced asthma", Lancet, 345(8956), pp.1056~ (1995)
- Buchheit KM, "Thymic stromal lymphopoietin controls prostaglandin D2 generation in patients with aspirin-exacerbated respiratory disease", J Allergy Clin Immunol, 137(5), pp.1566~1576 (2016)[DOI]
- Yamashita T, "Etiology of nasal polyps associated with aspirin-sensitive asthma", Rhinol Suppl, 8, pp.15~24 (1989)
- Sladek K, "Eicosanoids in bronchoalveolar lavage fluid of aspirin-intolerant patients with asthma after aspirin challenge", Am J Respir Crit Care Med, 149(4), pp.940~946 (1994)[DOI]
- Dekker JW, "Aspirin-induced asthma and HLA-DRB1 and HLA-DPB1 genotypes", Clin Exp Allergy, 27(5), pp.574~577 (1997)[DOI]
- Choi JH, "HLA association in aspirin-intolerant asthma: DPB1*0301 as a strong marker in a Korean population", J Allergy Clin Immunol, 113(3), pp.562~564 (2004)[DOI]
- Sanak M, "Leukotriene C4 synthase promoter polymorphism and risk of aspirin-induced asthma", Lancet, 350(9091), pp.1599~1600 (1997)[DOI]
- Choi JH, "Leukotriene-related gene polymorphisms in ASA-intolerant asthma: an association with a haplotype of 5-lipoxygenase", Hum Genet, 114(4), pp.337~344 (2004)[DOI]
- Jinnai N, "Polymorphisms in the prostaglandin E2 receptor subtype 2 gene confer susceptibility to aspirin-intolerant asthma: a candidate gene approach", Hum Mol Genet, 13(24), pp.3203~3217 (2004)[DOI]
- 박병래, "Association of PTGER gene family polymorphisms with aspirin intolerant asthma in Korean asthmatics", BMB Reports, 43(6), pp.445~449 (2010), 생화학분자생물학회
- Kim SH, "Association of thromboxane A2 receptor gene polymorphism with the phenotype of acetyl salicylic acid-intolerant asthma", Clin Exp Allergy, 35(5), pp.585~590 (2005)[DOI]
- Park JS, "Association analysis of cysteinyl-leukotriene receptor 2 (CYSLTR2) polymorphisms with aspirin intolerance in asthmatics", Pharmacogenet Genomics, 15(7), pp.483~492 (2005)[DOI]
- Kim SH, "Combined effect of IL-10 and TGF-beta1 promoter polymorphisms as a risk factor for aspirin-intolerant asthma and rhinosinusitis", Allergy, 64(8), pp.1221~1225 (2009)[DOI]
- Kohyama K, "IL-13 and IL-17A gene polymorphisms in Japanese patients with aspirin-exacerbated respiratory disease", Ann Allergy Asthma Immunol, 107(6), pp.510~516 (2011)[DOI]
- Bochenek G, "Testing for aspirin hypersensitivity", Allergy, 57(7), pp.562~565 (2002)[DOI]
- Nizankowska E, "Oral and bronchial provocation tests with aspirin for diagnosis of aspirin-induced asthma", Eur Respir J, 15(5), pp.863~869 (2000)[DOI]
- Rachel U. Lee, "Aspirin-Exacerbated Respiratory Disease: Evaluation and Management", Allergy, Asthma & Immunology Research, 3(1), pp.3~10 (2011), 대한천식알레르기학회
- Nizankowska-Mogilnicka E, "EAACI", GA2LEN guideline: aspirin provocation tests for diagnosis of aspirin hypersensitivity, 2007, pp.62(10), 1111~1118
- Melillo G, "Report of the INTERASMA Working Group on standardization of inhalation provocation tests in aspirin-induced asthma: oral and inhalation provocation tests for the diagnosis of aspirin-induced asthma", Allergy, 56(9), pp.899~911 (2001)[DOI]
- Nami Shrestha Palikhe, "Update on Recent Advances in the Management of Aspirin Exacerbated Respiratory Disease", Yonsei Medical Journal, 50(6), pp.744~750 (2009), 연세대학교의과대학
- Milewski M, "Nasal provocation test with lysine-aspirin for diagnosis of aspirin-sensitive asthma", J Allergy Clin Immunol, 101(5), pp.581~586 (1998)[DOI]
- Alonso-Llamazares A, "Nasal provocation test (NPT) with aspirin: a sensitive and safe method to diagnose aspirin-induced asthma (AIA)", Allergy, 57(7), pp.632~635 (2002)[DOI]
- White A, "Intranasal ketorolac challenge for the diagnosis of aspirin-exacerbated respiratory disease", Ann Allergy Asthma Immunol, 97(2), pp.190~195 (2006)[DOI]
- Lee RU, "Use of intranasal ketorolac and modified oral aspirin challenge for desensitization of aspirin-exacerbated respiratory disease", Ann Allergy Asthma Immunol, 105(2), pp.130~135 (2010)[DOI]
- Klimek L, "Aspirin intolerance: does desensitization alter the course of the disease?", Immunol Allergy Clin North Am, 29(4), pp.669~675 (2009)[DOI]
- Daffern PJ, "Association of urinary leukotriene E4 excretion during aspirin challenges with severity of respiratory responses", J Allergy Clin Immunol, 104(3), pp.559~564 (1999)[DOI]
- Jerschow E, "Utility of low-dose oral aspirin challenges for diagnosis of aspirin-exacerbated respiratory disease", Ann Allergy Asthma Immunol, 116(4), pp.321~328 (2016)[DOI]
- Antczak A, "Increased exhaled cysteinyl-leukotrienes and 8-isoprostane in aspirin-induced asthma", Am J Respir Crit Care Med, 166(3), pp.301~306 (2002)[DOI]
- Cahill KN, "Aspirin exacerbated respiratory disease: the search for a biomarker", Ann Allergy Asthma Immunol, 113(5), pp.500~501 (2014)[DOI]
- Chandrasekharan NV, "COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic", antipyretic drugs: cloning, structure, and expression, 2002, pp.99(21), 13926~13931
- Settipane RA, "Prevalence of cross-sensitivity with acetaminophen in aspirin-sensitive asthmatic subjects", J Allergy Clin Immunol, 96(4), pp.480~485 (1995)[DOI]
- Yoshida S, "Selective cyclo-oxygenase 2 inhibitor in patients with aspirin-induced asthma", J Allergy Clin Immunol, 106(6), pp.1201~1202 (2000)
- Szczeklik A, "Safety of a specific COX-2 inhibitor in aspirin-induced asthma", Clin Exp Allergy, 31(2), pp.219~225 (2001)[DOI]
- Stevenson DD, "Lack of cross-reactivity between rofecoxib and aspirin in aspirin-sensitive patients with asthma", J Allergy Clin Immunol, 108(1), pp.47~51 (2001)[DOI]
- Woessner KM, "The safety of celecoxib in patients with aspirin-sensitive asthma", Arthritis Rheum, 46(8), pp.2201~2206 (2002)[DOI]
- Inoue K, "Cyclooxygenase-2 inhibitors in aspirin-induced asthma", Chest, 123(4), pp.1317~1318 (2003)
- Gyllfors P, "Biochemical and clinical evidence that aspirin-intolerant asthmatic subjects tolerate the cyclooxygenase 2-selective analgetic drug celecoxib", J Allergy Clin Immunol, 111(5), pp.1116~1121 (2003)[DOI]
- Stevenson DD, "Selection of patients for aspirin desensitization treatment", J Allergy Clin Immunol, 118(4), pp.801~804 (2006)[DOI]
- Berges-Gimeno MP, "Long-term treatment with aspirin desensitization in asthmatic patients with aspirin-exacerbated respiratory disease", J Allergy Clin Immunol, 111(1), pp.180~186 (2003)[DOI]
- Stevenson DD, "Aspirin desensitization treatment of aspirin-sensitive patients with rhinosinusitis-asthma: long-term outcomes", J Allergy Clin Immunol, 98(4), pp.751~758 (1996)[DOI]
- Kowalski ML, "Clinical efficacy of aspirin in desensitised aspirin-sensitive asthmatics", Eur J Respir Dis, 69(4), pp.219~225 (1986)
- Rizk H, "Role of aspirin desensitization in the management of chronic rhinosinusitis", Curr Opin Otolaryngol Head Neck Surg, 19(3), pp.210~217 (2011)[DOI]
- Hope AP, "Rational approach to aspirin dosing during oral challenges and desensitization of patients with aspirin-exacerbated respiratory disease", J Allergy Clin Immunol, 123(2), pp.406~410 (2009)[DOI]
- Cho KS, "Long-term sinonasal outcomes of aspirin desensitization in aspirin exacerbated respiratory disease", Otolaryngol Head Neck Surg, 151(4), pp.575~581 (2014)[DOI]
- Swierczynska-Krepa M, "Aspirin desensitization in patients with aspirin-induced and aspirin-tolerant asthma: a double-blind study", J Allergy Clin Immunol, 134(4), pp.883~890 (2014)[DOI]
- Macy E, "Aspirin challenge and desensitization for aspirin-exacerbated respiratory disease: a practice paper", Ann Allergy Asthma Immunol, 98(2), pp.172~174 (2007)[DOI]
- Comert S, "Aspirin 300 mg", day is effective for treating aspirin-exacerbated respiratory disease, 2013, pp.68(11), 1443~1451
- Ortega-Loayza AG, "Aspirin desensitization", challenge in 3 patients with unstable angina, 2010, pp.340(5), 418~420
- Lee JY, "Selection of aspirin dosages for aspirin desensitization treatment in patients with aspirin-exacerbated respiratory disease", J Allergy Clin Immunol, 119(1), pp.157~164 (2007)[DOI]
- Rozsasi A, "Long-term treatment with aspirin desensitization: a prospective clinical trial comparing 100 and 300 mg aspirin daily", Allergy, 63(9), pp.1228~1234 (2008)[DOI]
- Namazy JA, "Sensitivity to nonsteroidal anti-inflammatory drugs", Ann Allergy Asthma Immunol, 89(6), pp.542~550 (2002)[DOI]
- Arm JP, "Leukotriene receptors and aspirin sensitivity", N Engl J Med, 347(19), pp.1524~1526 (2002)[DOI]
- Steinke JW, "Modulation by aspirin of nuclear phospho-signal transducer and activator of transcription 6 expression: possible role in therapeutic benefit associated with aspirin desensitization", J Allergy Clin Immunol, 124(4), pp.724~730 (2009)[DOI]
- White AA, "Does suppression of IL-4 synthesis by aspirin explain the therapeutic benefit of aspirin desensitization treatment?", J Allergy Clin Immunol, 126(4), pp.745~746 (2010)[DOI]
- Katial RK, "The effect of aspirin desensitization on novel biomarkers in aspirin-exacerbated respiratory diseases", J Allergy Clin Immunol, 126(4), pp.738~744 (2010)[DOI]
- Aksu K, "Effect of aspirin desensitization on T-cell cytokines and plasma lipoxins in aspirin-exacerbated respiratory disease", Allergy Asthma Proc, 35(2), pp.148~55 (2014)[DOI]
- Dahlen SE, "Improvement of aspirin-intolerant asthma by montelukast, a leukotriene antagonist: a randomized, double-blind, placebo-controlled trial", Am J Respir Crit Care Med, 165(1), pp.9~14 (2002)[DOI]
- Mastalerz L, "Intranasal fluticasone propionate for chronic eosinophilic rhinitis in patients with aspirin-induced asthma", Allergy, 52(9), pp.895~900 (1997)[DOI]
- Lee DK, "Montelukast protects against nasal lysine-aspirin challenge in patients with aspirin-induced asthma", Eur Respir J, 24(2), pp.226~230 (2004)[DOI]
- Ta V, "Survey-defined patient experiences with aspirin-exacerbated respiratory disease", J Allergy Clin Immunol Pract, 3(5), pp.711~718 (2015)[DOI]
- Wenzel S, "The safety and efficacy of zileuton controlled-release tablets as adjunctive therapy to usual care in the treatment of moderate persistent asthma: a 6-month randomized controlled study", J Asthma, 44(4), pp.305~310 (2007)[DOI]
- Hayashi H, "Omalizumab reduces cysteinyl leukotriene and <TEX>$9{\alpha}$<", TEX>,<TEX>$11{\beta}$<, J Allergy Clin Immunol, pp.2016, 137(5)[DOI]
- Kolbeck R, "MEDI-563, a humanized anti-IL-5 receptor alpha mAb with enhanced antibody-dependent cell-mediated cytotoxicity function", J Allergy Clin Immunol, 125(6), pp.1344~1353 (2010)[DOI]
- Varricchi G, "Interleukin-5 pathway inhibition in the treatment of eosinophilic respiratory disorders: evidence and unmet needs", Curr Opin Allergy Clin Immunol, 16(2), pp.186~200 (2016)[DOI]
- Laviolette M, "Effects of benralizumab on airway eosinophils in asthmatic patients with sputum eosinophilia", J Allergy Clin Immunol, 132(5), pp.1086~1096 (2013)[DOI]
- Hosemann W, "Surgical treatment of nasal polyposis in patients with aspirin intolerance", Thorax, 55(Suppl 2), pp.S87~S90 (2000)[DOI]
- McMains KC, "Medical and surgical considerations in patients with Samter's triad", Am J Rhinol, 20(6), pp.573~576 (2006)[DOI]
- Jang DW, "Aspirin sensitivity does not compromise quality-of-life outcomes in patients with Samter's triad", Laryngoscope, 124(1), pp.34~37 (2014)[DOI]
- Havel M, "Sinonasal outcome under aspirin desensitization following functional endoscopic sinus surgery in patients with aspirin triad", Eur Arch Otorhinolaryngol, 270(2), pp.571~578 (2013)[DOI]
- Batra PS, "Outcome analysis of endoscopic sinus surgery in patients with nasal polyps and asthma", Laryngoscope, 113(10), pp.1703~1706 (2003)
- Rotenberg BW, "Postoperative care for Samter's triad patients undergoing endoscopic sinus surgery: a double-blinded, randomized controlled trial", Laryngoscope, 121(12), pp.2702~2705 (2011)[DOI]
- Katotomichelakis M, "Allergic rhinitis and aspirin-exacerbated respiratory disease as predictors of the olfactory outcome after endoscopic sinus surgery", Am J Rhinol Allergy, 23(3), pp.348~353 (2009)[DOI]
- Adelman J, "The role of surgery in management of Samter's triad: a systematic review", Otolaryngol Head Neck Surg, 155(2), pp.220~237 (2016)[DOI]
- Loehrl TA, "Long-term asthma outcomes after endoscopic sinus surgery in aspirin triad patients", Am J Otolaryngol, 27(3), pp.154~160 (2006)[DOI]
- Awad OG, "Asthma outcomes after endoscopic sinus surgery in aspirin-tolerant versus aspirin-induced asthmatic patients", Am J Rhinol, 22(2), pp.197~203 (2008)[DOI]
