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빛간섭단층촬영을 이용한 당뇨환자의 백내장 수술 후 황반부종의 분석

Analysis of Postoperative Macular Edema in Cataract Patients with Diabetes using Optical Coherence Tomography

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목적: 당뇨를 동반한 환자들의 백내장 수술 후 황반부종의 발병율 또는 진행여부를 빛간섭단층촬영을 이용하여 알아보고, 수술 후황반부종의 위험인자에 대해 알아보고자 하였다. 대상과 방법: 백내장 수술을 시행한 당뇨환자 51명(66안)을 대상으로 수술 전, 수술 1개월 후, 수술 3개월 후 빛간섭단층촬영을 시행하고, 최대교정시력을 측정하였다. 황반부종은 망막 중심부 두께가 수술 전 측정치보다 30% 이상 증가한 경우로 정의하였다. 결과: 당뇨환자에서 백내장 수술 후 1개월째 황반부종의 발생률은 8.8%이었다. 당뇨병의 유병기간이 10년 이상인 환자들에서 10년이하인 환자들에 비해 수술 후 3개월째에는 황반두께의 증가량이 유의하게 컸으나(p=0.048), 인슐린 치료, 당뇨망막병증의 정도, 당뇨성 신장병증과 혈중 당산화혈색소는 황반부종에 유의한 위험인자가 아니었다. 결론: 당뇨환자의 백내장 수술 후 황반부종을 평가하는데 빛간섭단층촬영이 유용한 도구로 사용될 수 있으며, 당뇨 유병기간이 긴경우에는 황반부종의 유병률이 높을 수 있어 더욱 주의해야겠다.

Abstract

Purpose: To evaluate the incidence and progression of macular edema (ME) and associated risk factors in diabetic patients. Methods: In a prospective study, 66 eyes were assessed by optical coherence tomography (OCT) and best-corrected visual acuity was checked before operation at one and three months after operation. ME was defined as an increase of central macular thickness (CMT) by 30% or more after surgery than before operation, as measured by OCT. Results: The incidence of ME in diabetic patients was 8.8%. The increment of CMT at three months after cataract surgery was statistically significant in the patients of diabetic duration≥10years (p=0.049). But insulin treatment, the severity of diabetic retinopathy, diabetic nephropathy and hemoglobin A1C were not significant risk factors for ME. Conclusions: The OCT might be useful to assess the ME after cataract surgery in diabetic patients. In the patients who had long been suffered from diabetes, the incidence of ME could be higher, so cataract surgery should be carefully considered.

참고문헌 (18)

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