한국인 녹내장 환자에서 중심각막두께와 공막두께의 상관성
Relationship Between Central Corneal Thickness and Scleral Thickness in Korean Glaucomatous Patients
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목적: 한국인 녹내장 환자에서 중심각막두께와 공막두께의 상관성을 연구하고자 하였다. 대상과 방법: 녹내장(원발개방각 녹내장, 만성폐쇄각녹내장, 정상안압녹내장, 고안압증)으로 진단된 78명의 환자와 정상인 23명을 대상 으로 중심각막두께, 안축장길이, 전방깊이, 굴절이상, 공막두께를 측정하여 상관성을 비교하였다. 결과: 환자의 평균 연령은 57.32 ± 9.44세였다. 전체 환자의 평균 중심각막두께는 532.8 ± 43.75 μm였고, 각 질환별 비교에서는 고안 압증군(576.00 ± 26.59 μm)에서 정상대조군(530.30 ± 35.34 μm)에 비해 의미있게 두꺼웠다(p=0.00). 정상안압녹내장군의 평균 중심 각막두께(504.91 ± 41.16 μm)는 통계적으로 유의하게 정상대조군(530.30 ± 35.34 μm)에 비해 얇았다(p=0.028). 공막두께는 각 질환 군별 비교 결과 통계적으로 유의하지 않았다. 전체대상군 및 각 질환군 간에서 중심각막두께와 공막두께는 서로 유의한 상관관계를 보이지 않았다(r=-0.073,p=0.466). 결론: 중심각막두께와 공막두께와의 상관성은 통계학적으로 유의하지 않았다. 각 질병군별 비교에서도 공막두께는 통계학적인 유의한 차이는 보이지 않았다.
Abstract
Purpose: To evaluate the correlation between central corneal thickness (CCT) and scleral thickness (ST) in glaucoma patients. Methods: Seventy-eight eyes of 78 patients with no previous history of intraocular surgery and 23 control eyes were enrolled in the present study. For all eyes, CCT, ST, axial length, anterior chamber depth and refractive error were measured by a single examiner. The correlations among the measurements were analyzed. Results: The mean patient age was 57.32 ± 9.44 years, and the mean CCT was 532.80 ± 43.75 μm. The mean CCT of ocular hypertension (576.00 ± 26.59 μm) was thicker than that of the normal control group (530.30 ± 35.34 μm, p = 0.028), although the mean STs of the groups were not significantly different. No significant correlation was found between CCT and ST (r = -0.073, p = 0.466). Conclusions: In the present study, no correlation between CCT and ST was observed. In addition, the STs of the groups were not significantly different.
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