Seborrheic Keratosis of the Conjunctiva: A Case Report
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Seborrheic keratosis is a benign epithelial neoplasia that occurs mainly in the skin of the eyelids and face. We describe a case of seborrheic keratosis of the conjunctiva confirmed by histopathology. A 72-year-old man presented with a recurrent conjunctival mass involving the nasal side of his right eye. Clinically, a diagnosis of conjunctival papilloma was made, and a mass excision was performed. The histopathological analysis evidenced a conjunctival- covering epithelium with papillomatous changes and irregular acanthosis, at the expense of a proliferation of basaloid cells. In addition, the lesion exhibited multiple pseudohorn cysts containing keratin. With the above findings, a diagnosis of conjunctival seborrheic keratosis was established. The occurrence of seborrheic keratosis on the conjunctiva is rare. In this case, seborrheic keratosis was confirmed by pathologic report despite its similar appearance with papilloma. Seborrheic keratosis should be considered in the differential diagnosis of conjunctival lesions.
Abstract
Seborrheic keratosis is a benign epithelial neoplasia that occurs mainly in the skin of the eyelids and face. We describe a case of seborrheic keratosis of the conjunctiva confirmed by histopathology. A 72-year-old man presented with a recurrent conjunctival mass involving the nasal side of his right eye. Clinically, a diagnosis of conjunctival papilloma was made, and a mass excision was performed. The histopathological analysis evidenced a conjunctival- covering epithelium with papillomatous changes and irregular acanthosis, at the expense of a proliferation of basaloid cells. In addition, the lesion exhibited multiple pseudohorn cysts containing keratin. With the above findings, a diagnosis of conjunctival seborrheic keratosis was established. The occurrence of seborrheic keratosis on the conjunctiva is rare. In this case, seborrheic keratosis was confirmed by pathologic report despite its similar appearance with papilloma. Seborrheic keratosis should be considered in the differential diagnosis of conjunctival lesions.
참고문헌 (14)
- Duke-Elder S, "System of Ophthalmology, Vol. XIII, part I", pp.406~ (1974), Kimpton
- Albert DM, "Principles and Practice of Ophthalmology: Clinical Practice", pp.1716~1717 (1994), Saunders
- Moschella SL, "Dermatology, 3rd ed", pp.1722~1723 (1992), Saunders
- Yanoff M, "Ocular Pathology: A Text and Atlas, 2nd ed", pp.241~245 (1982), Harper & Row
- Wilkinson, "Rook", pp.Black- well Scientific, Ebling Textbook of Dermatology, 5th ed
- Tseng SH, "Seborrheic keratosis of conjunctiva simulating a malignant melanoma: an immunocytochemical study with impression cytology", Ophthalmology, 106, pp.1516~1520 (1999)
- Jain AK, "Seborrheic keratosis of the conjunctiva", Indian Journal of Ophthalmology, 52, pp.154~155 (2004)
- Gulias-Canizo R, "Seborrheic keratosis of conjunctiva: a case report", Arch Soc Esp Oftalmol, 81, pp.217~220 (2006)
- Seregard S, "Conjunctival melanoma", Surv Ophthalmol, 42, pp.321~350 (1998)
- Paridaens ADA, "Prognostic factors in primary malignant melanoma of the conjunctiva: a clinicopathological study of 256 cases", Br J Ophthalmol, 78, pp.252~259 (1994)
- Yanoff M, "Ocular Pathology: A Text and Atlas, 2nd ed", pp.800~804 (1982), Harper & Row
- Tsambaos D, "Detection of human papillomavirus DNA in nongenital seborrheic keratoses", Arch Dermatol Res, 287, pp.612~615 (1995)
- Cascajo CD, "Malignant neoplasia associated with seborrheic keratoses: an analysis of 54 cases", Am J Dermatopathol, 18, pp.278~282 (1996)
- LeBoit PE, "World Health Organization Classification of Tumours: Pathology and Gene- tics of Skin Tumours", pp.41~43 (2006), IARC Press