망막분지정맥폐쇄환자에서 정맥폐쇄 위치에 따른 임상적 양상
Clinical Features According to the Occlusion Site in Patients with Branch Retinal Vein Occlusion
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목적: 망막분지정맥폐쇄환자에서 폐쇄분지의 위치에 따라 임상적 양상을 알아보고자 한다. 대상과 방법: 망막분지정맥폐쇄 91안을 Duke-Elder and Wybar가 망막분지를 분류하였던 개념을 도입하여 폐쇄위치에 따라 유두주변정맥폐쇄군(A군), 주요정맥폐쇄군(B군), 부정맥폐쇄군(C군), 세정맥폐쇄군(D군)으로 나누어 초진 및 최종시력과 시력 호전정도, 황반부두께 및 주변 순환상태에 대해 분석하였다. 결과: 황반두께(μm)는 A군 575.33 ± 178.44, B군 511.92 ± 218.02, C군 397.21 ± 144.51, D군 336.68 ± 120.55, 망막의 허혈범위(DD)는 A군 22.00 ± 13.28, B군 18.26 ± 10.12, C군 12.52 ± 10.52, D군 12.36 ± 11.92으로 폐쇄분지가 상위일수록 황반두께가두껍고, 허혈범위가 넓었다(p＜0.05). 시력, 황반부주변 순환상태 등의 다른 인자에서는 네 군 간에 차이를 보이지 않았다. 결론: 망막분지정맥폐쇄에서 폐쇄분지의 위치가 망막의 허혈범위와 황반부종의 정도에 영향을 미치는 인자이나 이는 최종시력를 예측하는 인자는 아니었다.
Abstract
Purpose: To evaluate clinical patterns according to the occlusion site in patients with branch retinal vein occlusion. Methods: Ninety-one branch retinal vein occlusion patients were divided into 4 groups according to the occlusion site based on the description by Duke-Elder and Wybar: Papillary retinal vein occlusion group (group A), main retinal vein occlusion group (group B), minor retinal vein occlusion group (group C), and retinal venule occlusion group (group D). The following factors were analyzed retrospectively: baseline/final visual acuity, visual improvement, macular thickness, and macular circulatory states. Results: The macular thickness (μm) was 575.33 ± 178.44 in group A, 511.92 ± 218.02 in group B, 397.21 ± 144.51 in group C, and 336.68 ± 120.55 in group D. The retinal ischemic area (DD) was 22.00 ± 13.28 in group A, 18.26 ± 10.12 in group B, 12.52 ± 10.52 in group C, and 12.36 ± 11.92 in group D, which was found to be significantly greater in the group with the higher branch occlusion site (p < 0.05). However, visual acuity, macular circulatory states and other clinical characteristics were not significantly different. Conclusions: Occlusion site is a relating factor for retinal ischemic area and macular thickness in patients with Branch retinal vein occlussion, but which is not a prognostic factor for final visual acuity.
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