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한국인 개방성 안구손상 환자에 적용한 수정안외상점수의 유용성

The Availability of Modified Ocular Trauma Score in Korean Patients with Open Globe Injury

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목적: 한국인에서 개방성 안구 손상 환자의 임상 양상을 분석하여 안외상점수 계산 방법을 수정하고, 최종 시력의 예측에 수정 안외상점수의 유용성을 알아보고자 하였다. 대상과 방법: 저자들은 2000년 1월부터 2010년 9월까지 개방성 안구 손상으로 내원한 242명 242안을 대상으로 하여 안외상점수를계산할 때 사용되는 인자 중 안내염과 관통상 여부를 제외하고 손상 위치, 유리체 출혈, 수정체 손상 및 눈꺼풀 열상을 추가하여 국내실정에 맞도록 수정하였다. 수정된 안외상점수의 유용성을 확인하기 위하여 2010년 9월부터 2011년 12월까지 개방성 안구 손상으로내원한 29명 29안을 대상으로 의무 기록을 후향적으로 검토하여 수정된 안외상점수를 적용하였을 때 최종 시력이 0.02 미만인 경우에대한 양성예측도와 음성예측도를 계산하여 원래의 안외상점수 방법과 비교하였다. 결과: 안외상점수는 최종시력이 0.02 미만에 대한 양성예측도는 75.3%, 음성예측도는 90.8%가 되도록 수정되었다. 이는 원래의 안외상점수 방법의 양성예측도 70.1%, 음성예측도 89.8%보다 높았으나 통계적 차이는 보이지 않았다(p=0.5956, p=0.9370). 새로운 환자를 대상으로 적용하여 확인하였을 때 수정 안외상점수는 양성예측도 75.0%, 음성예측도 90.5%로 유용하였다. 결론: 수정된 안외상점수는 원래의 안외상점수 체계와 양성예측도 및 음성예측도가 유사하였으며, 국내 실정에 맞도록 인자가 조정되었으므로 향후 유용하게 사용될 수 있을 것으로 생각한다.

Abstract

Purpose: To modify the ocular trauma score (OTS) model by analyzing the clinical characteristics of Korean patients with open globe injury and to determine the availability of the modified OTS in predicting the final visual acuity. Methods: Among the prognostic factors in the original OTS, endophthalmitis and perforating injury were excluded, and wound location, vitreous hemorrhage, lens damage, and lid laceration were added to the modified OTS based on the data of 242 patients with open globe injury from January 2000 to September 2010. To determine the availability of the modified OTS, 29 patients from September 2010 to December 2011, not included in the previous data, were retrospectively reviewed,and the positive and negative predictive values for assessment of final visual acuity less than 0.02 were calculated by the original and modified OTS. Results: The modified OTS was applied to the previous data, and the positive predictive value was 75.3% and negative predictive value was 90.8%. By using the original OTS, the positive predictive value was 70.1% and negative predictive value was 89.8%. The values of the modified OTS was higher than those of the original OTS, but it was not statistically significant (p = 0.5956, p = 0.9370). When the modified OTS was applied to the new 29 patients, the positive and negative predictive values were 75.0% and 90.5%, respectively. Conclusions: The prognostic factors of the original OTS were modified based on the previous data and the positive and negative predictive values of final visual acuity by modified OTS were similar to those by the original OTS. The modified OTS would be useful in analyzing the patients with open globe injuries and could be used as a prognostic model for Korean patients.

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