Achromobacter xylosoxidans Keratitis after Contact Lens Usage
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To report on Achromobacter xylosoxidans keratitis in two healthy patients who had worn contact lenses foran extended period of time. A 36-year-old female and a 21-year-old female visited our hospital with ocular pain and blurred vision. Both patients had a history of wearing soft contact lenses for over fve years with occasional overnight wear. At the initial presentation, a slit lamp examination revealed corneal stromal infiltrations and epithelial defects with peripheral neovascularization in both patients. Microbiological examinations were performed from samples of corneal scrapings, contact lenses, contact lens cases, and solution. The culture resulting from the samples taken from the contact lenses, contact lens cases, and solution were all positive for Achromobacter xylosoxidans. Confrming that the direct cause of the keratitis was the contact lenses, the frst patient was prescribed ceftazidime and amikacin drops sensitive to Achromobacter xylosoxidans. The second patient was treated with 0.3% gatifoxacin and fortifed tobramycin drops. After treatment, the corneal epithelial defects were completely healed, and subepithelial corneal opacity was observed. Two cases of Achromobacter xylosoxidans keratitis were reported in healthy young females who wore soft contact lenses. Achromobacter xylosoxidans should be considered a rare but potentially harmful pathogen for lens-induced keratitis in healthy hosts.
Abstract
To report on Achromobacter xylosoxidans keratitis in two healthy patients who had worn contact lenses foran extended period of time. A 36-year-old female and a 21-year-old female visited our hospital with ocular pain and blurred vision. Both patients had a history of wearing soft contact lenses for over fve years with occasional overnight wear. At the initial presentation, a slit lamp examination revealed corneal stromal infiltrations and epithelial defects with peripheral neovascularization in both patients. Microbiological examinations were performed from samples of corneal scrapings, contact lenses, contact lens cases, and solution. The culture resulting from the samples taken from the contact lenses, contact lens cases, and solution were all positive for Achromobacter xylosoxidans. Confrming that the direct cause of the keratitis was the contact lenses, the frst patient was prescribed ceftazidime and amikacin drops sensitive to Achromobacter xylosoxidans. The second patient was treated with 0.3% gatifoxacin and fortifed tobramycin drops. After treatment, the corneal epithelial defects were completely healed, and subepithelial corneal opacity was observed. Two cases of Achromobacter xylosoxidans keratitis were reported in healthy young females who wore soft contact lenses. Achromobacter xylosoxidans should be considered a rare but potentially harmful pathogen for lens-induced keratitis in healthy hosts.
참고문헌 (24)
- Mandell WF, "Achromobacter xylosoxidans bacteremia", Rev Infect Dis, 9, pp.1001~1005 (1987)
- Spengler RF, "A descriptivestudy of nosocomial bacteremias at The Johns Hopkins Hospital, 1968-1974", Johns Hopkins Med J, (142), pp.77~84 (1978)
- Pien FD, "Achromobacter xylosoxidans isolates in Hawaii", J Clin Microbiol, 7, pp.239~241 (1978)
- Reverdy ME, "Nosocomial colonization and infection by Achromobacter xylosoxidans", J Clin Microbiol, 19, pp.140~143 (1984)
- Shigeta S, "Cerebral ventriculitis associated with Achromobacter xylosoxidans", J Clin Pathol, 31, pp.156~161 (1978)
- Yabuuchi E, "Achromobacter xylosoxidans n. sp. from human ear discharge", Jpn J Microbiol, 15, pp.477~481 (1971)
- Aisenberg G, "Bacteremia caused by Achromobacter and Alcaligenes species in 46 patients with cancer (1989-2003)", Cancer, 101, pp.2134~2140 (2004)
- Gomez-Cerezo J, "Achromobacter xylosoxidans bacteremia: a 10-year analysis of 54 cases", Eur J Clin Microbiol Infect Dis, 22, pp.360~363 (2003)
- Kish MA, "Bacteremia caused by Achromobacter species in an immunocompromised host", J Clin Microbiol, 19, pp.947~948 (1984)
- Knippschild M, "Infection by Alcaligenes xylosoxidans subsp. xylosoxidans in neutropenic patients", Oncology, 53, pp.258~262 (1996)
- Legrand C, "Bacteremia due to Achromobacter xylosoxidans in patients with cancer", Clin Infect Dis, 14, pp.479~484 (1992)
- Mizunoe S, "Case report: subcutaneous abscess and thoracic empyema caused by Alcaligenes xylosoxidans", Kansenshogaku Zasshi, 72, pp.631~634 (1998)
- Shie SS, "Characteristics of Achromobacter xylosoxidans bacteremia in northern Taiwan", J Microbiol Immunol Infect, 38, pp.277~282 (2005)
- Tsay RW, "Alcaligenes xylosoxidans bacteremia: clinical features and microbiological characteristics of isolates", J Microbiol Immunol Infect, 38, pp.194~199 (2005)
- Weitkamp JH, "Recurrent Achromobacter xylosoxidans bacteremia associated with persistent lymph node infection in a patient with hyper-immunoglobulin M syndrome", Clin Infect Dis, 31, pp.1183~1187 (2000)
- Reddy AK, "Clinical, microbiological profile and treatment outcome of ocular infections caused by Achromobacter xylosoxidans", Cornea, 28, pp.1100~1103 (2009)
- Slusher MM, "Extended-wear lenses, biofilm, and bacterial adhesion", Arch Ophthalmol, 105, pp.110~115 (1987)
- Bruce AS, "Corneal pathophysiology with contact lens wear", Surv Ophthalmol, 35, pp.25~58 (1990)
- Newman PE, "Corneal ulcer due to Achromobacter xylosoxidans", Br J Ophthalmol, 68, pp.472~474 (1984)
- Huang ZL, "Recurrent Alcaligenes xylosoxidans keratitis", Cornea, 24, pp.489~490 (2005)
- Fiscella R, "Achromobacter xylosoxidans corneal ulcer in a therapeutic soft contact lens wearer", Cornea, 8, pp.267~269 (1989)
- Srinivasan S, "Bilateral simultaneous Achromobacter xylosoxidans keratitis following penetrating keratoplasty", J Cataract Refract Surg, 32, pp.2149~2152 (2006)
- Pan TH, "Delayed onset and recurrent Alcaligenes xylosoxidans keratitis", Cornea, 19, pp.243~245 (2000)
- Linke SJ, "Bilateral Achromobacter xylosoxidans keratitis after laser in situ keratomileusis", J Cataract Refract Surg, 36, pp.1045~1047 (2010)