광각 디지털 영상 장치를 이용한 정상 신생아의 안과 선별 검사 결과
Findings of Eye Screening Examinations with Wide-Field Digital Imaging System in Healthy Newborns
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목적: 건강한 신생아에서 RetCam을 이용하여 시행한 안과 선별검사의 결과를 보고하고자 한다. 대상과 방법: 2012년 6월부터 2014년 9월까지 쉬즈메디 여성병원 외 8곳의 산부인과 병원에서 출생한 건강한 신생아 중 안과검사를희망한 경우 RetCam wide-field digital imaging system (Clarity Medical System, Pleasanton, CA, USA)을 이용하여 출생 1주 내에검사를 시행하였다. 검사는 적색반사가 보이는 사진과 안저를 촬영하였고, 한 명의 소아안과의사에 의하여 판독이 이루어졌다. 결과: 총 10,023명의 신생아에서 검사가 이루어졌고, 2,916명(29.09%)의 환아에서 이상이 발견되었다. 가장 많은 이상은 망막출혈이었고 2,796명(27.89%)에서 발견되었으며 471명은 출혈의 양이 많거나 황반부 출혈을 동반했다. 71명(0.7%)에서 선천 백내장, 망막모세포종, 일차 유리체 증식증, 유리체 출혈, 동공막 잔존, 맥락막 모반, 백색증 등이 발견되어 안과검사를 권유하였다. 49명 85안(0.48%)은 사진이 선명하지 않아 판독이 불가능하였다. 결론: RetCam을 이용한 신생아의 안과 선별검사는 안전하며 간단하게 안과 이상 유무를 알 수 있는 유용한 검사법이다. 그리고 이상이 의심되는 경우 적절한 안과진료를 받을 수 있도록 하는 소아안과의사의 역할이 점점 중요해질 것으로 생각되며, 이상의 대부분을차지하는 망막출혈의 경우 그 양이 많거나 황반부가 침범될 경우 이후 약시 발생 등의 가능성에 대한 추가 연구가 필요할 것으로 생각된다.
Abstract
Purpose: To present the results of eye screening examinations using RetCam in healthy newborns. Methods: Eye screening examinations were performed using the RetCam wide-field digital imaging system (Clarity Medical System, Pleasanton, CA, USA), as requested by parents, on healthy newborns within a week after birth in an obstetrics and gynecology hospital between June 2012 and September 2014. During the examination, photographs were taken showing red reflex and the fundus. The reading was conducted by a pediatric ophthalmologist. Results: The examinations included a total of 10,023 newborn babies, and abnormalities were discovered in 2,916 patients (29.09%). The most commonly found abnormality was retinal hemorrhage, which was discovered in 2,796 babies (27.89%) and 471 patients showed a large amount of bleeding or macular hemorrhage. In 71 patients (0.7%), ophthalmologic examination was recommended after newborns presented with one of the following conditions: congenital cataracts, retinoblastoma, persistent hyperplastic primary vitreous, vitreous hemorrhaging, persistent pupillary membrane, choroidal nevus or albinism. Due to unclear photographs, 85 eyes of 49 patients (0.48%) could not be read. Conclusions: Ophthalmologic screening using RetCam is a safe, simple and useful technique for discovering ophthalmologic abnormalities. Additionally, when abnormalities are suspected, the role of a pediatric ophthalmologist is increasingly important in helping patients receive appropriate ophthalmologic treatment. Furthermore, retinal hemorrhage, which occurred in the majority of all observed abnormalities, requires further investigation to examine the possibilities of amblyopia in cases with a large amount of bleeding or macula involvement.
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