Fluorescein Angiographic Abnormalities in the Contralateral Eye with Normal Fundus in Children with Unilateral Coats’ Disease
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We report the detection of peripheral retinal vascular abnormalities in the fellow eye with normal fundusin children with unilateral Coats’ disease. Methods: The clinical records of patients diagnosed with Coats’ disease were retrospectively reviewed. Werecorded the subjects’ characteristics and obtained fundus photography and fluorescein angiography (FA) images. The main outcome measure was peripheral vascular abnormalities in the contralateral eye with normalfundus in children with unilateral Coats’ disease, observed with FA. Results: Out of 47 patients with Coats’ disease, two (4.3%) were diagnosed with clinically bilateral Coats’ disease. Of the 45 patients with presumed unilateral Coats’ disease, four (8.9%) had bilateral abnormal peripheralvasculature in FA. The mean age of these four patients was 6.4 ± 5.4 years (range, 1 to 14 years), and threepatients were male (75%). All four had peripheral retinal nonperfusion, and two (50%) received laser photocoagulationdue to peripheral leakage with telangiectatic vessels. Conclusions: Coats’ disease may more often be a bilateral disease with asymmetry than previously thought. Patients with Coats’ disease should undergo careful examination of the fellow eye with FA in order to detectand treat vascular abnormalities that are not visible clinically.
Abstract
We report the detection of peripheral retinal vascular abnormalities in the fellow eye with normal fundusin children with unilateral Coats’ disease. Methods: The clinical records of patients diagnosed with Coats’ disease were retrospectively reviewed. Werecorded the subjects’ characteristics and obtained fundus photography and fluorescein angiography (FA) images. The main outcome measure was peripheral vascular abnormalities in the contralateral eye with normalfundus in children with unilateral Coats’ disease, observed with FA. Results: Out of 47 patients with Coats’ disease, two (4.3%) were diagnosed with clinically bilateral Coats’ disease. Of the 45 patients with presumed unilateral Coats’ disease, four (8.9%) had bilateral abnormal peripheralvasculature in FA. The mean age of these four patients was 6.4 ± 5.4 years (range, 1 to 14 years), and threepatients were male (75%). All four had peripheral retinal nonperfusion, and two (50%) received laser photocoagulationdue to peripheral leakage with telangiectatic vessels. Conclusions: Coats’ disease may more often be a bilateral disease with asymmetry than previously thought. Patients with Coats’ disease should undergo careful examination of the fellow eye with FA in order to detectand treat vascular abnormalities that are not visible clinically.
참고문헌 (18)
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