백내장수술 후 발생한 스트렙토코커스 디스갈락티아에 의한 안내염 1예
A Case of Streptococcus dysgalactiae Endophthalmitis after Cataract Surgery
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목적: 국내에서 보고된 적이 없는 백내장수술 후 발생한 Streptococcus dysgalactiae에 의한 안내염 1예를 경험하였기에 이를 보고하고자 한다. 증례요약: 65세 남자 환자가 좌안 백내장수술을 받은 후 발생한 안내염으로 본원으로 전원하였다. 내원 당시 좌안 시력은 광각인지였으며 전방 및 유리체강내 염증이 심하여 좌안 유리체절제술, 인공수정체 제거술, 유리체강내 항생제 및 스테로이드 주입술을 시행하고 유리체액과 전방수로 배양검사를 시행하였다. 술 중 시행한 유리체 배양검사에서 Streptococcus dysgalactiae가 동정되었다. 하지만 술 후에도 전방 및 유리체강내 염증이 점점 심해져 술 후 4일째 전방세척술, 유리체강내 항생제 주입술을 시행하였다. 술 후 25일째 퇴원하였으며 퇴원 당시에도 각막 윤부 신생혈관, 각막 위축, 각막 부종, 침윤, 전방 축농이 지속되었다. 외래 경과 관찰 중 시력은 광각인지 불가로 진행하였으며 안구위축이 진행하는소견을 보였다. 결론: Streptococcus dysgalactiae에 의한 안내염은 매우 드문 질환으로 국내에서 보고된 적이 없으며, 저자들은 적극적인 치료에도 불구하고 예후가 좋지 않았던 안내염 1예를 경험하였기에 이를 보고하는 바이다.
Abstract
Purpose: To report the first case of endophthalmitis due to Streptococcus dysgalactiae after phacoemulsification and posterior chamber intraocular lens implantation in the Republic of Korea. Case summary: A 65-year-old male was transferred because of endophthalmitis following cataract surgery. His initial visual acuity was light perception. Because inflammation of the anterior chamber and vitreous cavity progressed rapidly, we performed total pars planar vitrectomy and intraocular lens extraction in addition to administering intravitreal antibiotics and intravitreal dexamethasone injections. Streptococcus dysgalactiae was identified in samples cultured from the vitreous and anterior chamber fluid. Four days after surgery, we washed the anterior chamber and intravitreal antibiotics were again injected because of increased inflammation of the anterior chamber and vitreous. The patient was discharged 25 days after surgery but corneal neovascularization, contraction, edema, infiltration, and hypopyon remained. Visual acuity progressed to no light perception and there was shrinkage of the globe. Conclusions: Endophthalmitis due to Streptococcus dysgalactiae is very rare. We report the first case of endophthalmitis caused by Streptococcus dysgalactiae in the Republic of Korea. The prognosis for recovery was poor despite aggressive treatment.
참고문헌 (25)
- Mamalis N, "Endophthalmitis", J Cataract Refract Surg, 28, pp.729~730 (2002)[DOI]
- Jabbarvand M, "Endophthalmitis occurring after cataract surgery: outcomes of more than 480 000 cataract surgeries, epidemiologic features, and risk factors", Ophthalmology, 123, pp.295~301 (2016)[DOI]
- Lancefield RC, "A serological differentiation of human and other groups of hemolytic streptococci", J Exp Med, 57, pp.571~595 (1933)[DOI]
- Higgs TM, "Differences in intramammary pathogenicity of four strains of Streptococcus dysgalactiae", J Med Microbiol, 13, pp.393~399 (1980)[DOI]
- Sylvetsky N, "Bacteremia due to beta-hemolytic Streptococcus group G: increasing incidence and clinical characteristics of patients", Am J Med, 112, pp.622~626 (2002)[DOI]
- Ruppen C, "A 10-year observational study of Streptococcus dysgalactiae bacteraemia in adults: frequent occurrence among female intravenous drug users", Swiss Med Wkly, 147, pp.w14469~ (2017)
- Rantala S, "Streptococcus dysgalactiae subsp. equisimilis bacteremia: an emerging infection", Eur J Clin Microbiol Infect Dis, 33, pp.1303~1310 (2014)[DOI]
- Brandt CM, "Human infections due to Streptococcus dysgalactiae subspecies equisimilis", Clin Infect Dis, 49, pp.766~772 (2009)[DOI]
- Takahashi T, "Invasive infection caused by Streptococcus dysgalactiae subsp. equisimilis: characteristics of strains and clinical features", J Infect Chemother, 17, pp.1~10 (2011)
- Ramaswamy G, "Streptococcus equisimilis (group C) as a cause of ophthalmic infections", Am J Clin Pathol, 79, pp.385~387 (1983)[DOI]
- Wickramasinghe N, "Bilateral endophthalmitis as a primary manifestation of Streptococcus dysgalactiae endocarditis and the role of 16S rDNA polymerase chain reaction in identification", Diagn Microbiol Infect Dis, 67, pp.185~187 (2010)[DOI]
- Yong AS, "Streptococcus dysgalactiae endocarditis presenting as acute endophthalmitis", Infect Dis Rep, 4, pp.e16~ (2012)[DOI]
- Kaliamurthy J, "Post-operative ocular infection due to Streptococcus dysgalactiae subspecies equisimilis", J Infect Dev Ctries, 5, pp.742~744 (2011)
- Miller JJ, "Acute-onset endophthalmitis after cataract surgery (2000-2004): incidence, clinical settings, and visual acuity outcomes after treatment", Am J Ophthalmol, 139, pp.983~987 (2005)[DOI]
- Vaziri K, "Endophthalmitis: state of the art", Clin Ophthalmol, 9, pp.95~108 (2015)
- Ravindran RD, "Incidence of post-cataract endophthalmitis at Aravind Eye Hospital: outcomes of more than 42,000 consecutive cases using standardized sterilization and prophylaxis protocols", J Cataract Refract Surg, 35, pp.629~636 (2009)[DOI]
- Endophthalmitis Vitrectomy Study Group, "Results of the Endophthalmitis Vitrectomy Study: A randomized trial of immediate vitrectomy and of intravenous antibiotics for the treatment of postoperative bacterial endophthalmitis", Arch Ophthalmol, 113, pp.1479~1496 (1995)[DOI]
- Ciszewski M, "Potential factors enabling human body colonization by animal streptococcus dysgalactiae subsp. equisimilis Strains", Curr Microbiol, 74, pp.650~654 (2017)[DOI]
- Wolfe ND, "Origins of major human infectious diseases", Nature, 447, pp.279~283 (2007)[DOI]
- Schrieber L, "Transmission of Streptococcus dysgalactiae subsp. equisimilis between child and dog in an Aboriginal Australian community", Zoonoses Public Health, 61, pp.145~148 (2014)[DOI]
- Silva LG, "Group C Streptococcus dysgalactiae subsp. equisimilis in south-east Brazil: genetic diversity, resistance profile and the first report of human and equine isolates belonging to the same multilocus sequence typing lineage", J Med Microbiol, 64, pp.551~558 (2015)[DOI]
- McNeilly CL, "Horizontal gene transfer and recombination in Streptococcus dysgalactiae subsp. equisimilis", Front Microbiol, 5, pp.676~ (2014)
- Broyles LN, "Population-based study of invasive disease due to beta-hemolytic streptococci of groups other than A and B", Clin Infect Dis, 48, pp.706~712 (2009)[DOI]
- Lott MN, "Vitreal penetration of oral moxifloxacin in humans", Retina, 28, pp.473~476 (2008)[DOI]
- Hooper CY, "Adjunctive antibiotics in the treatment of acute bacterial endophthalmitis following cataract surgery", Acta Ophthalmol, 90, pp.e572~e573 (2012)[DOI]
