외상반복각막진무름에서 치료콘택트렌즈 장기 착용과 5% NaCl 점안액 병용치료 효과
The Clinical Result of Extended Wear of Therapeutic Contact Lenses and 5% NaCl for Traumatic Recurrent Corneal Erosion
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목적: 외상성 반복각막진무름 환자들에서 치료콘택트렌즈의 장기 착용과 5% NaCl 점안액 유지 병용치료의 효과를 알아보고자 하였다. 대상과 방법: 2015년 1월부터 2017년 12월까지 본원 안과에서 외상에 의한 반복각막진무름을 처음 진단 받은 환자 18명 18안을 대상으로 환자들의 나이, 성별, 외상 원인을 분석하고, 치료콘택트렌즈 장기 착용과 5% NaCl 점안액을 유지 병용치료 후 반복각막진무름의 재발률, 재발 시기, 치료 후 최대교정시력, 합병증 유무에 대해 후향적 연구를 시행하였다. 결과: 환자 평균 나이는 50.0 ± 12.0세(27-75세)였고, 성별의 차이는 없었다. 평균 관찰기간은 11.6 ± 7.4개월(3.5-28.0개월)이었다. 18안 중 치료 후 재발한 환자는 3안(16.7%)이었고 3안 모두 치료콘택트렌즈 착용과 5% NaCl 점안액을 유지한 후 증상이 소실되었다. 18명 환자의 치료 전 최대교정시력은 0.35 ± 0.33 logarithm of minimal angle of resolution (logMAR)이고 치료 후 최종 최대교정시력은 0.09 ± 0.06 logMAR이었다(p=0.015). 치료콘택트렌즈의 장기 착용에 의한 세균각막염이나 저산소증, 무균침윤 등의 부작용은없었다. 결론: 외상반복각막진무름 환자에서 치료콘택트렌즈의 장기 착용과 5% NaCl 점안액 장기간 병용치료는 안전하고 효과적인 치료 방법으로 생각된다.
Abstract
Purpose: To evaluate the clinical results of treatment with extended wear of therapeutic contact lenses and 5% NaCl eye drops for traumatic recurrent corneal erosion. Methods: From January 2015 to December 2017, 18 eyes of 18 patients who were first diagnosed with recurrent corneal erosion after trauma were analyzed. The age, sex, and causes of injury of the patients were analyzed. We retrospectively analyzed the recurrence rate, recurrence time, best-corrected visual acuity (BCVA), and complications after treatment with extended wear of therapeutic contact lenses and 5% NaCl eye drops. Results: The mean age was 50.0 ± 12.0 years (range: 27-75 years) with no significant difference in gender and the mean follow up period was 11.6 ± 7.4 months (range: 3.5-28.0 months). Three eyes (16.7%) experienced recurrences and all of them were resolved with a therapeutic contact lens and 5% NaCl eye drops. The initial mean BCVA was 0.35 ± 0.33 logarithm of minimal angle of resolution (logMAR) and the final mean BCVA was 0.09 ± 0.06 logMAR (p = 0.015). There were no significant complications such as bacterial keratitis, hypoxia or sterile infiltration from the extended wear of therapeutic contact lenses. Conclusions: The results imply that long-term combined treatment of extended therapeutic contact lens wear with 5% NaCl eye drops may be a safe and effective therapy.
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