눈꺼풀테에 생긴 전염물렁종: 임상 증례 및 문헌 고찰
Molluscum Contagiosum of the Eyelid Margin: a Case Series and Literature Review
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목적: 눈꺼풀테에 생긴 전염물렁종 9예를 보고하고, 이와 관련된 문헌 고찰을 통해 임상 양상에 대해 알아보고자 한다. 대상과 방법: 눈꺼풀테 전염물렁종에 대해 진단 및 치료받은 9명의 환자의 의무기록을 후향적으로 분석하였다. 결과: 9명 중 8명의 환자들이 여자였고, 평균 연령은 6.1세였다. 모든 환자는 다른 전신 이상이 없고 감염, 면역기능 이상이 없는 건강한 환자였으며, 덧눈꺼풀이 있던 2예를 제외하고 모두 다른 안과적 이상이 없었다. 피부병변의 개수는 1개에서 6개까지 다양했고, 절제생검에서 모두 편평상피의 안쪽으로 파고드는 모양의 소엽증식, 바닥층 바로 위쪽 각질형성세포 내의 봉입체 소견이 관찰되었다. 수술 치료 후 모든 환자들은 합병증 및 재발 없이 유지되었다. 결론: 눈꺼풀테에도 전염물렁종이 생길 수 있고, 이 경우 다른 신체 부위의 전염물렁종과는 달리 개수가 적고 서로 떨어져 있으며 병변의 모양이 비전형적인 양상으로 나타날 수 있다. 또한 눈꺼풀테에 생기는 전염물렁종은 각결막염 등과 같은 안구 합병증을 유발할 수 있어 초기에 적극적 수술 치료가 필요할 수 있다.
Abstract
Purpose: We report 9 cases of molluscum contagiosum of the eyelid margin and a literature review. Methods: A retrospective, observational case series of 9 patients who were diagnosed with molluscum contagiosum of the eyelid margin. Results: Subjects included 8 female patients and 1 male patient with an average age of 6.1 years. The patients were all healthy without any underlying disease, and their blood analyses and chest X-rays excluded any infectious disease or immune-related problem. Each patient had 1–6 skin lesions. Hematoxylin and eosin staining revealed lobular hyperplasia of the squamous epithelium, which invaded into the underlying dermis. Staining also revealed inclusion bodies in the cytoplasm of keratinocytes above the basal layer. All patients were maintained without complications or recurrence after surgical treatment. Conclusions: Molluscum contagiosum on the eyelid margin differs from those on other body parts. Subjects had fewer lesions and lesion shapes were atypical. Early surgical treatment may be necessary because molluscum contagiosum can lead to ocular complications such as conjunctivitis.
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