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Bilateral Ophthalmic Artery Occlusion in Rhino-Orbito-Cerebral Mucormycosis

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Purpose: To report a case of bilateral ophthalmic artery occlusion in rhino-orbito-cerebral mucormycosis. Methods: Reviewed clinical charts, photographs, and fluorescein angiography Results: An 89-year-old man with poorly controlled diabetes developed sudden bilateral ptosis, complete ophthalmoplegia of the right eye, and superior rectus palsy of the left eye. Brain and orbit magnetic resonance imaging showed midbrain infarction and mild diffuse sinusitis. On the 2nd day of hospitalization, sudden visual loss and light reflex loss developed. There were retinal whitening, absence of retinal arterial filling, and a total lack of choroidal perfusion on fluorescein angiography of the right eye. The left eye showed a cherry red spot in the retina and the absence of retinal arterial filling and partial choroidal perfusion on fluorescein angiography. On rhinologic examination, mucormyosis was noticed. Despite treatment, visual acuity and light reflex did not recover and he died 4 days after admission. Conclusions: Bilateral ophthalmic artery occlusion can occur in rhino-orbital-cerebral mucormycosis.

Abstract

Purpose: To report a case of bilateral ophthalmic artery occlusion in rhino-orbito-cerebral mucormycosis. Methods: Reviewed clinical charts, photographs, and fluorescein angiography Results: An 89-year-old man with poorly controlled diabetes developed sudden bilateral ptosis, complete ophthalmoplegia of the right eye, and superior rectus palsy of the left eye. Brain and orbit magnetic resonance imaging showed midbrain infarction and mild diffuse sinusitis. On the 2nd day of hospitalization, sudden visual loss and light reflex loss developed. There were retinal whitening, absence of retinal arterial filling, and a total lack of choroidal perfusion on fluorescein angiography of the right eye. The left eye showed a cherry red spot in the retina and the absence of retinal arterial filling and partial choroidal perfusion on fluorescein angiography. On rhinologic examination, mucormyosis was noticed. Despite treatment, visual acuity and light reflex did not recover and he died 4 days after admission. Conclusions: Bilateral ophthalmic artery occlusion can occur in rhino-orbital-cerebral mucormycosis.

참고문헌 (6)

  1. Vessely VB, "Atypical presentations of mucormycosis in the head and neck", Otolaryngol Head Neck Surg, 115, pp.573~7 (1996)
  2. Ferry AP, "Diagnosis and management of rhino- orbitocerebral mucormycosis", Ophthalmology, 90, pp.1096~104 (1983)
  3. Onerci M, "Rhinocerebral mucormycosis with extention to the cavernous sinus", Rhinology, 29, pp.321~4 (1991)
  4. Bendet E, "Rhino‐orbito-cerebral mucormycosis", Otolaryngol Head Neck Surg, 114, pp.830~2 (1996)
  5. Yang SW, "Two cases of orbital infarction syndrome", Korean J Ophthalmol, 14, pp.107~11 (2000)
  6. Brown GC, "Arterial obstruction and ocular neovascularization", Ophthalmology, 89, pp.139~46 (1982)

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