전안부 빛간섭단층촬영을 이용한 검열반의 양상 분석
Features of Pinguecula Analyzed by Anteroir Segment Optical Coherence Tomography
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목적: 전안부 빛간섭단층촬영을 이용하여 검열반의 임상양상과 검열반의 공막침범 정도의 상관관계를 분석하고자 하였다. 대상과 방법: 2017년 2월부터 2018년 4월까지 검열반을 주소로 본원에 내원한 환자 50명(남자 17명, 여자 33명)을 대상으로 하여 검열반의 크기, 융기 정도, 색깔, 혈관화 정도를 조사하였고 전안부 빛간섭단층촬영을 시행하여 두께와 공막침범 정도를 분석하였다. 결과: 검열반의 수평직경은 평균 2.37 ± 1.12 mm로 검열반 두께 및 단면적과 유의한 양의 상관관계를 보였다(상관계수: 각 0.34, 0.42). 수직직경은 평균 2.21 ± 0.91 mm로서 검열반의 두께, 공막침범 정도, 단면적 모두와 유의한 양의 상관관계를 보였으며(상관계수: 각 0.22, 0.61, 0.33) 공막침범 두께와의 상관계수도 0.61로 높았다. 평균직경 또한 평균 2.29 ± 0.97 mm로서 검열반 두께, 단면적과 유의한 상관관계를 보였다(상관계수: 각 0.40, 0.54). 검열반 전체 두께는 심한 융기 그룹이 평균 두께 0.66 ± 0.35 mm로 0.57 ± 0.23 mm의 편평 그룹보다 유의하게 두꺼운 양상을 보였고, 혈관화가 심한 그룹이 0.70 ± 0.19 mm로 0.52 ± 0.13 mm의 경한 그룹보다 유의하게 두꺼웠다(p=0.01). 결론: 크기가 크고 혈관화 정도가 높은 검열반이 두께도 두껍고 공막침범도도 심함을 전안부 빛간섭단층촬영을 통해 객관적으로 확인할 수 있었다.
Abstract
Purpose: To analyze the correlation between clinical features and degree of scleral invasion using anterior segment optical coherence tomography. Methods: The size, elevation, color, and degree of vascularization were examined in 50 patients (17 males and 33 females) who visited our clinic between February 2017 and April 2018. The thickness and scleral involvement were analyzed by anterior segment optical coherence tomography. Results: The average horizontal diameter of the pinguecula was 2.37 ± 1.12 mm, which showed significant positive correlations with the thickness and dimension (correlation coefficients: 0.34 and 0.42, respectively). The vertical diameter was 2.21 ± 0.91 mm, which showed significant correlations with thickness, scleral involvement, and dimension (correlation coefficients: 0.22, 0.61, and 0.33, respectively). The correlation coefficient with scleral invasion thickness was as high as 0.61. The average diameter was 2.29 ± 0.97 mm, which was also significantly correlated with thickness and dimension (correlation coefficients: 0.40 and 0.54, respectively). Overall thickness was significantly greater in the elevation group (average 0.66 ± 0.35 mm) than the flat group (0.57 ± 0.23 mm). Thickness was significantly greater in the severe vascularization group (0.70 ± 0.19 mm) than in the less severe vascularization group (0.50 ± 0.13 mm) (p = 0.01). Conclusions: Anterior segment OCT findings revealed that the larger and more vascularized pinguecula were significantly thicker and had more scleral involvement.
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