The Effect of an Intravitreal Triamcinolone Acetonide Injection for Acute Nonarteritic Anterior Ischemic Optic Neuropathy
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The purpose of this case report is to evaluate the visual outcome of an intravitreal triamcinolone acetonide injection (IVTA) as a treatment for a patient with acute nonarteritic anterior ischemic optic neuropathy (NAION). A 65-year-old male patient with severe visual loss due to acute NAION was treated with 4 ㎎/0.1㎖ IVTA. Fundus examination and measurements of the patient’s best-corrected visual acuity and visual field were performed before and after the injection at 2 weeks, 1 month, 3 months, and 6 months. The best-corrected visual acuity changed from 0.05 before the injection to 0.16 at 2 weeks, 0.3 at 1 month, and 0.4 at 3 months and at the final visit. Optic disc swelling had markedly decreased at 1 week postoperatively and disappeared at 2 weeks after the injection. The clinical course of this patient suggests that an IVTA may be effective in increasing visual acuity following an acute NAION. A large randomized controlled trial is needed to assess the efficacy of IVTA as a treatment for NAION.
Abstract
The purpose of this case report is to evaluate the visual outcome of an intravitreal triamcinolone acetonide injection (IVTA) as a treatment for a patient with acute nonarteritic anterior ischemic optic neuropathy (NAION). A 65-year-old male patient with severe visual loss due to acute NAION was treated with 4 ㎎/0.1㎖ IVTA. Fundus examination and measurements of the patient’s best-corrected visual acuity and visual field were performed before and after the injection at 2 weeks, 1 month, 3 months, and 6 months. The best-corrected visual acuity changed from 0.05 before the injection to 0.16 at 2 weeks, 0.3 at 1 month, and 0.4 at 3 months and at the final visit. Optic disc swelling had markedly decreased at 1 week postoperatively and disappeared at 2 weeks after the injection. The clinical course of this patient suggests that an IVTA may be effective in increasing visual acuity following an acute NAION. A large randomized controlled trial is needed to assess the efficacy of IVTA as a treatment for NAION.
참고문헌 (9)
- Repka MX, "Clinical profile and long-term implications of anterior ischemic neuropathy", Am J Ophthalmol, 96, pp.478~483 (1983)
- Martin TJ, "Neuro-ophthalmology: The requisites in ophthalmology, 1st ed", pp.62~67 (2000), Mosby
- Beck RW, "Optic disc structure in anterior ischemic optic neuropathy", Ophthalmology, 91, pp.1334~1337 (1984)
- 김대현, "한국인 앞허혈시신경병증의 위험인자", 대한안과학회지, 48(11), pp.1527~1531 (2007), 대한안과학회
- Beck RW, "Aspirin therapy in nonarteritic anterior ischemic optic neuropathy", Am J Ophthalmol, 123, pp.212~217 (1997)
- Kaderli B, "Intravitreal triamcinolone improves recovery of visual acuity in nonarteritic anterior ischemic optic neuropathy", J Neuro Ophthalmol, 27, pp.164~168 (2007)
- Jonas JB, "Intravitreal triamcinolone acetonide for treatment of acute nonarteritic anterior ischemic optic neuropathy", Graefes Arch Clin Exp Ophthalmol, 245, pp.749~750 (2007)
- Hayreh SS, "Nonarteritic anterior ischemic optic neuropathy: Natural history of visual outcome", Ophthalmology, 115, pp.298~305 (2008)
- Knox DL, "Histopathologic studies of ischemic optic neuropathy", Trans Am Opthalmol Soc, 98, pp.203~220 (2000)
