A Case of Vogt-Koyanagi-Harada Disease ina Patient With Graves Disease
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A case of Vogt-Koyanagi-Harada disease (VKH) that developed in a 36-year-old woman with Graves’ disease was described. The patient was treated with Lugol’s solution and presented with bilateral serous retinal detachment. She had also suffered from methimazole-induced hypersensitivity and steroid-induced myopathy. Fluorescein angiography showed multiple leakage points and a lumbar puncture revealed pleocytosis, which was compatible with VKH. High dose steroid pulse therapy was successful. Altered immune regulation associated with drug-induced hypersensitivity may contribute to the development of VKH in patients with Graves’ disease.
Abstract
A case of Vogt-Koyanagi-Harada disease (VKH) that developed in a 36-year-old woman with Graves’ disease was described. The patient was treated with Lugol’s solution and presented with bilateral serous retinal detachment. She had also suffered from methimazole-induced hypersensitivity and steroid-induced myopathy. Fluorescein angiography showed multiple leakage points and a lumbar puncture revealed pleocytosis, which was compatible with VKH. High dose steroid pulse therapy was successful. Altered immune regulation associated with drug-induced hypersensitivity may contribute to the development of VKH in patients with Graves’ disease.
참고문헌 (4)
- Read RW, "Revised diagnostic criteria for Vogt-Koyanagi-Harada disease: report of an international committee on nomenclature", Am J Ophthalmol, 131, pp.647~652 (2001)
- Chi HI, "Vogt-Koyanagi-Harada’s syndrome associated with Hashimoto’s thyroiditis", J Dermatol, 21, pp.683~686 (1994)
- Gocho K, "Identification of autoreactive T cells in Vogt-Koyanagi-Harada disease", Invest Ophthalmol Vis Sci, 42, pp.2004~2009 (2001)
- Streetman DD, "Diagnosis and treatment of Graves Disease", Ann Phamacother, 37, pp.1100~1109 (2003)