Clinical Features of Strabismus in Patients with Congenital Optic Disc Anomaly
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Purpose: To investigate the clinical features of strabismus in patients with congenital optic disc anomaly and compare andanalyze the characteristics of patients who showed changes in the strabismus pattern with those who did not. Methods: Medical records of the patients who were diagnosed with both strabismus and congenital optic disc anomaly andfollowed-up for ≥1 year were reviewed retrospectively. Clinical characteristics and ophthalmic features at the initial visit andfinal follow-up were assessed. Patients with a change in the direction of strabismus or a difference of >10 prism diopters inthe deviation angle during the follow-up period were allocated to the changed group. The remaining patients were assignedto the unchanged group. The clinical characteristics of the two groups were compared. Results: Twenty-eight patients (15 boys) were included (mean age, 39.0 months; range, 5–150 months). Three (10.7%) patientswere born preterm and four (14.3%) had other underlying systemic disease. Sixteen (57.1%) patients had exotropia, and12 (42.9%) had esotropia. Concurrent vertical strabismus was present in three (10.7%) patients. Strabismus features changedin 14 (50.0%, changed group) patients and remained unchanged in 14 (50.0%, unchanged group) patients. Age, sex, and lateralitydid not differ between groups. Preterm birth history (n = 3) and combined systemic disease (n = 4) were only observed inthe changed group (p = 0.111 and p = 0.049, respectively). Conclusions: Considering the possibility of changes in strabismic features, close monitoring of patients with strabismus combinedwith congenital disc anomaly is essential, particularly in those with preterm birth history or underlying systemic conditions.
Abstract
Purpose: To investigate the clinical features of strabismus in patients with congenital optic disc anomaly and compare andanalyze the characteristics of patients who showed changes in the strabismus pattern with those who did not. Methods: Medical records of the patients who were diagnosed with both strabismus and congenital optic disc anomaly andfollowed-up for ≥1 year were reviewed retrospectively. Clinical characteristics and ophthalmic features at the initial visit andfinal follow-up were assessed. Patients with a change in the direction of strabismus or a difference of >10 prism diopters inthe deviation angle during the follow-up period were allocated to the changed group. The remaining patients were assignedto the unchanged group. The clinical characteristics of the two groups were compared. Results: Twenty-eight patients (15 boys) were included (mean age, 39.0 months; range, 5–150 months). Three (10.7%) patientswere born preterm and four (14.3%) had other underlying systemic disease. Sixteen (57.1%) patients had exotropia, and12 (42.9%) had esotropia. Concurrent vertical strabismus was present in three (10.7%) patients. Strabismus features changedin 14 (50.0%, changed group) patients and remained unchanged in 14 (50.0%, unchanged group) patients. Age, sex, and lateralitydid not differ between groups. Preterm birth history (n = 3) and combined systemic disease (n = 4) were only observed inthe changed group (p = 0.111 and p = 0.049, respectively). Conclusions: Considering the possibility of changes in strabismic features, close monitoring of patients with strabismus combinedwith congenital disc anomaly is essential, particularly in those with preterm birth history or underlying systemic conditions.
참고문헌 (15)
- Brodsky MC, "Pediatric neuro-ophthalmology", pp.75~109 (2010), Springer
- Kushner BJ, "Functional amblyopia associated with abnormalities of the optic nerve", Arch Ophthalmol, 102, pp.683~685 (1984)
- Kim MR, "Clinical feature analysis of congenital optic nerve abnormalities", Jpn J Ophthalmol, 50, pp.250~255 (2006)
- Garcia ML, "Systemic and ocular findings in 100 patients with optic nerve hypoplasia", J Child Neurol, 21, pp.949~956 (2006)
- Berk AT, "Ocular and systemic findings associated with optic disc colobomas", J Pediatr Ophthalmol Strabismus, 40, pp.272~278 (2003)
- Scanlon PH, "Visual acuity measurement and ocular co-morbidity in diabetic retinopathy screening", Br J Ophthalmol, 92, pp.775~778 (2008)
- Erkan Turan K, "Bilateral optic disc pathologies as an accompanying feature of comitant strabismus in children", Int Ophthalmol, 38, pp.425~428 (2018)
- Siatkowski RM, "The clinical, neuroradiographic, and endocrinologic profile of patients with bilateral optic nerve hypoplasia", Ophthalmology, 104, pp.493~496 (1997)
- Golnik KC, "Congenital optic nerve anomalies", Curr Opin Ophthalmol, 9, pp.18~26 (1998)
- Bradford GM, "Results of amblyopia therapy in eyes with unilateral structural abnormalities", Ophthalmology, 99, pp.1616~1621 (1992)
- Fu VL, "Progression of intermittent, small-angle, and variable esotropia in infancy", Invest Ophthalmol Vis Sci, 48, pp.661~664 (2007)
- VanderVeen DK, "Prevalence and course of strabismus in the first year of life for infants with prethreshold retinopathy of prematurity: findings from the Early Treatment for Retinopathy of Prematurity study", Arch Ophthalmol, 124, pp.766~773 (2006)
- Pediatric Eye Disease Investigator Group, "Spontaneous resolution of early-onset esotropia: experience of the Congenital Esotropia Observational Study", Am J Ophthalmol, 133, pp.109~118 (2002)
- Brodsky MC, "Congenital optic disk anomalies", Surv Ophthalmol, 39, pp.89~112 (1994)
- Hoyt CS, "Do we really understand the difference between optic nerve hypoplasia and atrophy?", Eye (Lond), 6, pp.201~204 (1992)