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논문KCI 등재

Piroxicam에 의한 고정약진 1예: Meloxicam과의 교차항원성

A Case of Fixed Drug Eruption by Piroxicam: Cross Antigenicity between Piroxicam and Meloxicam

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참고문헌

주제분류임상병리학

초록

Abstract

Piroxicam, a derivative of oxicam and COX-1 inhibitor, is a widely used nonsteroidal anti-inflammatory drug. The common cutaneous reaction by piroxicam is photosensitivity rather than fixed drug eruption. We experienced fixed cutaneuos lesion with antibiotics and piroxicam three times and confirmed piroxicam-induced fixed drug eruption withoral challenge test. This patient also showed the positive reaction to meloxicam, a kind of COX-2 inhibitor, derived from oxicam, which present the cross antigenicity between piroxicam.

참고문헌 (6)

  1. "An expanded profile of cutaneous reactions to nonsteroidal anti-inflammatory drugs Reports to a specialty- based system for spontaneous reporting of adverse reactions to drugs", pp.1433~7
  2. "Cross- reactivity among oxicams", more(-zazo m), pp.133~6
  3. "Cross-sensitivity among oxicams in piroxicam-caused fixed drug eruption", pp.741~4
  4. "Fixed drug eruption from piroxicam with positive lesional patch test"
  5. "Fixed drug eruption to rofecoxib with cross-reactivity to sulfonamides", pp.351~3
  6. "Celecoxib-induced fixed drug eruption", pp.452~3

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