Fluorquinolone 항생제에 교차반응을 보인 ofloxacin 에 의한 아나필락시양 반응 1례
Anaphylactoid reaction to ofloxacin with cross-reactivity to other fluoroquinolones
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Abstract
Fluoroquinolones are antimicrobial agents that have a broad range of activity against both gram-negative and gram-positive organisms. Anaphylactoid reactions have been sporadically reported with fluoroquinolones. There have been a few reports that describes cross-reactivity between fluoroquinolones. We experienced a case of ofloxacin-induced anaphylactoid reaction, and confirmed cross-reactivity between ofloxacin and ciprofloxacin with the oral challenge test. Cross-reactivity between fluoroquinolones may be important, and avoidance of any fluoroquinolones should be mandatory for patients with hypersensitivity reaction to one of these drugs. (J Asthma Allergy Clin Immunol 24: 146-51, 2004)
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