항원출처 유발검사로 진단된 건초더미에 의한 과민성폐렴 1예
A Case of Stored Hay-induced Hypersensitivity Pneumonitis Diagnosed with Inhalational Provocation Tests Using Antigen Sources
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Hypersensitivity pneumonitis (HP) is an immunologically mediated disease which is developed by repeated exposure to sensitizing agents, such as organic dusts or chemicals. The majority of cases occur in the occupational or agricultural setting. We report a case of HP caused by stored hay for feeding cows. A 47-year-old woman has suffered from repeated episodes of cough and dyspnea accompanied by flu-like symptoms, which developed or worsened during feeding cows. Provocation tests with stored hay dusts revealed decreased FEV1 and FVC, blood leukocytosis and lymphocytosis in bronchoalveolar lavage fluid with decreased CD4+/CD8+ ratio. This case suggests that provocation tests with the antigen sources would be valuable when the diagnosis is unclear or when clinical data are insufficient. (Korean J Asthma Allergy Clin Immunol 2008;28:226- 230)
Abstract
Hypersensitivity pneumonitis (HP) is an immunologically mediated disease which is developed by repeated exposure to sensitizing agents, such as organic dusts or chemicals. The majority of cases occur in the occupational or agricultural setting. We report a case of HP caused by stored hay for feeding cows. A 47-year-old woman has suffered from repeated episodes of cough and dyspnea accompanied by flu-like symptoms, which developed or worsened during feeding cows. Provocation tests with stored hay dusts revealed decreased FEV1 and FVC, blood leukocytosis and lymphocytosis in bronchoalveolar lavage fluid with decreased CD4+/CD8+ ratio. This case suggests that provocation tests with the antigen sources would be valuable when the diagnosis is unclear or when clinical data are insufficient. (Korean J Asthma Allergy Clin Immunol 2008;28:226- 230)
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