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Post–intensive-care morbidity among pediatric patients in Thailand: prevalence, risk factors, and the importance of the post–intensive-care clinic

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Background: Long-term survival data for critically ill children discharged to post-intensive care clinics are scarce, especially in Asia. The main objective of this study was to assess the prevalence of post–intensive-care morbidity among pediatric intensive care unit (PICU) survivors at 1 month and 1 year after hospital discharge and to identify the associated risk factors.Methods: We conducted a retrospective chart review of all children aged 1 month to 15 years who were admitted to the PICU for >48 hours from July 2019 to July 2022 and visited a post–intensive-care clinic 1 month and 1 year after hospital discharge. Post-intensive care morbidity was defined using the Pediatric Cerebral Performance Category (PCPC). Descriptive statistics, univariate, and multivariate analyses were conducted.Results: A total of 111 children visited the clinic at 1 month, and 100 of these children visited the clinic at 1 year. Only 39 of 111 children (35.2%) had normal PCPC assessments at 1 month, while 54 of 100 (54.0%) were normal at 1 year. Baseline developmental delays were significantly associated with any degree of disability and at least moderate disability at both time points. Mechanical ventilation for >7 days was associated with at least moderate disability at both time points, while PICU stay >7 days was significantly associated with moderate disability at 1 month and any degree of disability at 1 year.Conclusions: A substantial percentage of PICU survivors had persistent disabilities even 1 year after critical illness. A structured multidisciplinary post–intensive-care follow-up plan is warranted to provide optimal care for such children.

Abstract

Background: Long-term survival data for critically ill children discharged to post-intensive care clinics are scarce, especially in Asia. The main objective of this study was to assess the prevalence of post–intensive-care morbidity among pediatric intensive care unit (PICU) survivors at 1 month and 1 year after hospital discharge and to identify the associated risk factors.Methods: We conducted a retrospective chart review of all children aged 1 month to 15 years who were admitted to the PICU for >48 hours from July 2019 to July 2022 and visited a post–intensive-care clinic 1 month and 1 year after hospital discharge. Post-intensive care morbidity was defined using the Pediatric Cerebral Performance Category (PCPC). Descriptive statistics, univariate, and multivariate analyses were conducted.Results: A total of 111 children visited the clinic at 1 month, and 100 of these children visited the clinic at 1 year. Only 39 of 111 children (35.2%) had normal PCPC assessments at 1 month, while 54 of 100 (54.0%) were normal at 1 year. Baseline developmental delays were significantly associated with any degree of disability and at least moderate disability at both time points. Mechanical ventilation for >7 days was associated with at least moderate disability at both time points, while PICU stay >7 days was significantly associated with moderate disability at 1 month and any degree of disability at 1 year.Conclusions: A substantial percentage of PICU survivors had persistent disabilities even 1 year after critical illness. A structured multidisciplinary post–intensive-care follow-up plan is warranted to provide optimal care for such children.

참고문헌 (22)

  1. Manning JC, "Conceptualizing post intensive care syndrome in children : the PICS-p framework", Pediatr Crit Care Med, 19, pp.298~300 (2018)
  2. Inoue S, "Post-intensive care syndrome : its pathophysiology, prevention, and future directions", Acute Med Surg, 6, pp.233~246 (2019)
  3. Herrup EA, "Characteristics of postintensive care syndrome in survivors of pediatric critical illness : a systematic review", World J Crit Care Med, 6, pp.124~134 (2017)
  4. Ong C, "Functional outcomes and physical impairments in pediatric critical care survivors : a scoping review", Pediatr Crit Care Med, 17, pp.e247~e259 (2016)
  5. Als LC, "Mental and physical well-being following admission to pediatric intensive care", Pediatr Crit Care Med, 16, pp.e141~e149 (2015)
  6. Jones S, "Outcome at 6 months after admission for pediatric intensive care : a report of a national study of pediatric intensive care units in the United kingdom", Pediatrics, 118, pp.2101~2108 (2006)
  7. Gemke RJ, "Long-term survival and state of health after paediatric intensive care", Arch Dis Child, 73, pp.196~201 (1995)
  8. Tippayawong P, "Incidence and associated factors of pediatric post-intensive care syndrome using the VSCAREMD model", Acute Crit Care, 37, pp.627~635 (2022)
  9. Als LC, "Neuropsychologic function three to six months following admission to the PICU with meningoencephalitis, sepsis, and other disorders : a prospective study of school-aged children", Crit Care Med, 41, pp.1094~1103 (2013)
  10. Colville G, "Patterns of post-traumatic stress symptoms in families after paediatric intensive care", Intensive Care Med, 38, pp.1523~1531 (2012)
  11. Dow BL, "The diagnosis of posttraumatic stress disorder in school-aged children and adolescents following pediatric intensive care unit admission", J Child Adolesc Psychopharmacol, 23, pp.614~619 (2013)
  12. Walz A, "The ICU liberation bundle and strategies for implementation in pediatrics", Curr Pediatr Rep, 8, pp.69~78 (2020)
  13. Snell K, "Post-intensive care unit clinic(PICUC)role in decreasing 60-day readmissions : a prospective study", Crit Care Med, 46, pp.590~ (2018)
  14. de Sonnaville ES, "Long-term follow-up of daily life functioning after pediatric intensive care unit admission", J Pediatr, 260, pp.113477~ (2023)
  15. Fiser DH, "Assessing the outcome of pediatric intensive care", J Pediatr, 121, pp.68~74 (1992)
  16. Volaki EM, "Functional outcome following pediatric intensive care : Pediatric Cerebral Performance Category(PCPC)and Pediatric Overall Performance Category(POPC)during a prospective two years follow-up period", Greek eJ Perioper Med, 13, pp.2~15 (2015)
  17. Pollack MM, "PRISM III : an updated Pediatric Risk of Mortality score", Crit Care Med, 24, pp.743~752 (1996)
  18. Belletti A, "Vasoactive-inotropic score : evolution, clinical utility, and pitfalls", J Cardiothorac Vasc Anesth, 35, pp.3067~3077 (2021)
  19. Odetola F, "What challenges still exist in the critical care of children?", BMC Pediatr, 22, pp.592~ (2022)
  20. Heneghan JA, "Outcome measures following critical illness in children with disabilities : a scoping review", Front Pediatr, 9, pp.689485~ (2021)
  21. Fink EL, "A core outcome set for pediatric critical care", Crit Care Med, 48, pp.1819~1828 (2020)
  22. Fiser DH, "Relationship of illness severity and length of stay to functional outcomes in the pediatric intensive care unit : a multi-institutional study", Crit Care Med, 28, pp.1173~1179 (2000)

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