New insight into transglutaminase 2 and link to neurodegenerative diseases

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참고문헌 (77)

1. Sarkar NK, "An enzymically catalyzed incorporation of amines into proteins", Biochim Biophys Acta, 25, pp.451~452 (1957)[DOI]
2. Grenard P, "Evolution of transglutaminase genes: identification of a transglutaminase gene cluster on human chromosome 15q15. Structure of the gene encoding transglutaminase X and a novel gene family member, transglutaminase Z", J Biol Chem, 276, pp.33066~33078 (2001)[DOI]
3. Mehta K, "Mammalian transglutaminases: a family portrait", Prog Exp Tumor Res, 38, pp.1~18 (2005)
4. Park D, "Transglutaminase 2: a multi-functional protein in multiple subcellular compartments", Amino Acids, 39, pp.619~631 (2010)[DOI]
5. Achyuthan KE, "Identification of a guanosine triphosphate-binding site on guinea pig liver transglutaminase. Role of GTP and calcium ions in modulating activity", J Biol Chem, 262, pp.1901~1906 (1987)
6. Nakaoka H, "Gh: a GTP-binding protein with transglutaminase activity and receptor signaling function", Science, 264, pp.1593~1596 (1994)[DOI]
7. Hasegawa G, "A novel function of tissue-type transglutaminase: protein disulphide isomerase", Biochem J, 373, pp.793~803 (2003)[DOI]
8. Jones RA, "Reduced expression of tissue transglutaminase in a human endothelial cell line leads to changes in cell spreading, cell adhesion and reduced polymerisation of fibronectin", J Cell Sci, 110, pp.2461~2472 (1997)
9. Mishra S, "The p53 oncoprotein is a substrate for tissue transglutaminase kinase activity", Biochem Biophys Res Commun, 339, pp.726~730 (2006)[DOI]
10. Mishra S, "Tissue transglutaminase has intrinsic kinase activity: identification of transglutaminase 2 as an insulin-like growth factor-binding protein-3 kinase", J Biol Chem, 279, pp.23863~23868 (2004)[DOI]
11. Lorand L, "Transglutaminases: crosslinking enzymes with pleiotropic functions", Nat Rev Mol Cell Biol, 4, pp.140~156 (2003)[DOI]
12. Takeuchi Y, "Nuclear translocation of tissue type transglutaminase during sphingosine-induced cell death: a novel aspect of the enzyme with DNA hydrolytic activity", Z Naturforsch C, 53, pp.352~358 (1998)
13. Nurminskaya MV, "Cellular functions of tissue transglutaminase", Int Rev Cell Mol Biol, 294, pp.1~97 (2012)
14. Esposito C, "Mammalian transglutaminases. Identification of substrates as a key to physiological function and physiopathological relevance", FEBS J, 272, pp.615~631 (2005)[DOI]
15. Lesort M, "Tissue transglutaminase: a possible role in neurodegenerative diseases", Prog Neurobiol, 61, pp.439~463 (2000)[DOI]
16. Dieterich W, "Identification of tissue transglutaminase as the autoantigen of celiac disease", Nat Med, 3, pp.797~801 (1997)[DOI]
17. Sollid LM, "Autoantibodies in coeliac disease: tissue transglutaminase--guilt by association?", Gut, 41, pp.851~852 (1997)[DOI]
18. Birckbichler PJ, "Transglutaminase activity in normal and transformed cells", Cancer Res, 37, pp.1340~1344 (1977)
19. Griffin M, "Changes in transglutaminase activity in an experimental model of pulmonary fibrosis induced by paraquat", Br J Exp Pathol, 60, pp.653~661 (1979)
20. Gentile V, "The human tissue transglutaminase gene maps on chromosome 20q12 by in situ fluorescence hybridization", Genomics, 20, pp.295~297 (1994)[DOI]
21. Fesus L, "Transglutaminase 2: an enigmatic enzyme with diverse functions", Trends Biochem Sci, 27, pp.534~539 (2002)[DOI]
22. Fraij BM, "Organization and structure of the human tissue transglutaminase gene", Biochim Biophys Acta, 1354, pp.65~71 (1997)[DOI]
23. Kiraly R, "Protein transamidation by transglutaminase 2 in cells: a disputed Ca2+-dependent action of a multifunctional protein", FEBS J, 278, pp.4717~4739 (2011)[DOI]
24. Shrestha R, "Molecular mechanism by which acyclic retinoid induces nuclear localization of transglutaminase 2 in human hepatocellular carcinoma cells", Cell Death Dis, 6, pp.e2002~ (2015)[DOI]
25. Murthy SN, "Conserved tryptophan in the core domain of transglutaminase is essential for catalytic activity", Proc Natl Acad Sci U S A, 99, pp.2738~2742 (2002)[DOI]
26. Lee KN, "Sitedirected mutagenesis of human tissue transglutaminase: Cys-277 is essential for transglutaminase activity but not for GTPase activity", Biochim Biophys Acta, 1202, pp.1~6 (1993)[DOI]
27. Yee VC, "Structure and function studies of factor XIIIa by x-ray crystallography", Semin Thromb Hemost, 22, pp.377~384 (1996)[DOI]
28. Pinkas DM, "Transglutaminase 2 undergoes a large conformational change upon activation", PLoS Biol, 5, pp.e327~ (2007)[DOI]
29. Kuo TF, "New insights into the functions and localization of nuclear transglutaminase 2", FEBS J, 278, pp.4756~4767 (2011)[DOI]
30. Milakovic T, "Intracellular localization and activity state of tissue transglutaminase differentially impacts cell death", J Biol Chem, 279, pp.8715~8722 (2004)[DOI]
31. Malorni W, "The adenine nucleotide translocator 1 acts as a type 2 transglutaminase substrate: implications for mitochondrialdependent apoptosis", Cell Death Differ, 16, pp.1480~1492 (2009)[DOI]
32. Stephens P, "Crosslinking and G-protein functions of transglutaminase 2 contribute differentially to fibroblast wound healing responses", J Cell Sci, 117, pp.3389~3403 (2004)[DOI]
33. Mhaouty-Kodja S, "Ghalpha", tissue transglutaminase 2: an emerging G protein in signal transduction, 2004, pp.96, 363~367
34. Dupuis M, "Functional coupling of rat myometrial alpha 1-adrenergic receptors to Gh alpha", tissue transglutaminase 2 during pregnancy, 2004, pp.279, 19257~19263
35. Stamnaes J, "Redox regulation of transglutaminase 2 activity", J Biol Chem, 285, pp.25402~25409 (2010)[DOI]
36. DiRaimondo TR, "Selective inhibition of extracellular thioredoxin by asymmetric disulfides", J Med Chem, 56, pp.1301~1310 (2013)[DOI]
37. Shin DM, "TGFbeta mediates activation of transglutaminase 2 in response to oxidative stress that leads to protein aggregation", FASEB J, 22, pp.2498~2507 (2008)[DOI]
38. Begg GE, "Mutation of a critical arginine in the GTP-binding site of transglutaminase 2 disinhibits intracellular cross-linking activity", J Biol Chem, 281, pp.12603~12609 (2006)[DOI]
39. Fabbi M, "Tissue transglutaminase is a caspase substrate during apoptosis. Cleavage causes loss of transamidating function and is a biochemical marker of caspase 3 activation", Cell Death Differ, 6, pp.992~1001 (1999)[DOI]
40. Luciani A, "SUMOylation of tissue transglutaminase as link between oxidative stress and inflammation", J Immunol, 183, pp.2775~2784 (2009)[DOI]
41. Ku BM, "Transglutaminase 2 inhibition found to induce p53 mediated apoptosis in renal cell carcinoma", FASEB J, 27, pp.3487~3495 (2013)[DOI]
42. Min B, "CHIP-mediated degradation of transglutaminase 2 negatively regulates tumor growth and angiogenesis in renal cancer", Oncogene, 35, pp.3718~3728 (2016)[DOI]
43. Norlund MA, "Elevated transglutaminase-induced bonds in PHF tau in Alzheimer's disease", Brain Res, 851, pp.154~163 (1999)[DOI]
44. Johnson GV, "Transglutaminase activity is increased in Alzheimer's disease brain", Brain Res, 751, pp.323~329 (1997)[DOI]
45. Shinagawa R, "In vitro neurotoxicity of amyloid beta-peptide cross-linked by transglutaminase", Cytotechnology, 23, pp.77~85 (1997)[DOI]
46. Curro M, "Transglutaminase 2 silencing reduced the beta-amyloid-effects on the activation of human THP-1 cells", Amino Acids, 39, pp.1427~1433 (2010)[DOI]
47. Hartley DM, "Transglutaminase induces protofibril-like amyloid beta-protein assemblies that are protease-resistant and inhibit long-term potentiation", J Biol Chem, 283, pp.16790~16800 (2008)[DOI]
48. Boros S, "Transglutaminase catalyzes differential crosslinking of small heat shock proteins and amyloid-beta", FEBS Lett, 576, pp.57~62 (2004)[DOI]
49. de Jager M, "Tissue transglutaminase colocalizes with extracellular matrix proteins in cerebral amyloid angiopathy", Neurobiol Aging, 34, pp.1159~1169 (2013)[DOI]
50. Zhang W, "Pharmacologic inhibition of transglutaminase-induced cross-linking of Alzheimer's amyloid beta-peptide", Life Sci, 60, pp.2323~2332 (1997)[DOI]
51. Zemaitaitis MO, "Transglutaminase-induced cross-linking of tau proteins in progressive supranuclear palsy", J Neuropathol Exp Neurol, 59, pp.983~989 (2000)[DOI]
52. Tucholski J, "Tau is modified by tissue transglutaminase in situ: possible functional and metabolic effects of polyamination", J Neurochem, 73, pp.1871~1880 (1999)
53. Halverson RA, "Tau protein is cross-linked by transglutaminase in P301L tau transgenic mice", J Neurosci, 25, pp.1226~1233 (2005)[DOI]
54. Kalia LV, "Parkinson's disease", Lancet, 386, pp.896~912 (2015)[DOI]
55. Forno LS, "Neuropathology of Parkinson's disease", J Neuropathol Exp Neurol, 55, pp.259~272 (1996)[DOI]
56. Lin MK, "Genetics and genomics of Parkinson's disease", Genome Med, 6, pp.48~ (2014)[DOI]
57. Chai C, "Genetic insights into sporadic Parkinson's disease pathogenesis", Curr Genomics, 14, pp.486~501 (2013)
58. Beck KE, "The role of tissue transglutaminase in 1-methyl-4-phenylpyridinium (MPP+)-induced toxicity in differentiated human SH-SY5Y neuroblastoma cells", Neurosci Lett, 405, pp.46~51 (2006)[DOI]
59. Verhaar R, "Blockade of enzyme activity inhibits tissue transglutaminasemediated transamidation of alpha-synuclein in a cellular model of Parkinson's disease", Neurochem Int, 58, pp.785~793 (2011)[DOI]
60. Junn E, "Tissue transglutaminase-induced aggregation of alpha-synuclein: Implications for Lewy body formation in Parkinson's disease and dementia with Lewy bodies", Proc Natl Acad Sci U S A, 100, pp.2047~2052 (2003)[DOI]
61. Schmid AW, "Dissecting the mechanisms of tissue transglutaminase-induced crosslinking of alpha-synuclein: implications for the pathogenesis of Parkinson disease", J Biol Chem, 284, pp.13128~13142 (2009)[DOI]
62. Sato H, "Authentically phosphorylated alpha-synuclein at Ser129 accelerates neurodegeneration in a rat model of familial Parkinson's disease", J Neurosci, 31, pp.16884~16894 (2011)[DOI]
63. Min B, "PINK1 phosphorylates transglutaminase 2 and blocks its proteasomal degradation", J Neurosci Res, 93, pp.722~735 (2015)[DOI]
64. Verhaar R, "Increase in endoplasmic reticulum-associated tissue transglutaminase and enzymatic activation in a cellular model of Parkinson's disease", Neurobiol Dis, 45, pp.839~850 (2012)[DOI]
65. Wilhelmus MM, "Presence of tissue transglutaminase in granular endoplasmic reticulum is characteristic of melanized neurons in Parkinson's disease brain", Brain Pathol, 21, pp.130~139 (2011)[DOI]
66. Gibrat C, "Cystamine prevents MPTP-induced toxicity in young adult mice via the up-regulation of the brain-derived neurotrophic factor", Prog Neuropsychopharmacol Biol Psychiatry, 34, pp.193~203 (2010)[DOI]
67. Tremblay ME, "Neuroprotective effects of cystamine in aged parkinsonian mice", Neurobiol Aging, 27, pp.862~870 (2006)[DOI]
68. Davies SW, "Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation", Cell, 90, pp.537~548 (1997)[DOI]
69. Zainelli GM, "Calmodulin regulates transglutaminase 2 cross-linking of huntingtin", J Neurosci, 24, pp.1954~1961 (2004)[DOI]
70. Mastroberardino PG, "'Tissue' transglutaminase ablation reduces neuronal death and prolongs survival in a mouse model of Huntington's disease", Cell Death Differ, 9, pp.873~880 (2002)[DOI]
71. Bailey CD, "Tissue transglutaminase contributes to disease progression in the R6", 2 Huntington's disease mouse model via aggregateindependent mechanisms, 2005, pp.92, 83~92
72. Sun L, "Effects of cysteamine on MPTP-induced dopaminergic neurodegeneration in mice", Brain Res, 1335, pp.74~82 (2010)[DOI]
73. Sung K, "Functional glass surface displaying a glutamyl donor substrate for transglutaminase-mediated protein immobilization", Biotechnol J, 5, pp.456~462 (2010)[DOI]
74. Karpuj MV, "Prolonged survival and decreased abnormal movements in transgenic model of Huntington disease, with administration of the transglutaminase inhibitor cystamine", Nat Med, 8, pp.143~149 (2002)[DOI]
75. Dedeoglu A, "Therapeutic effects of cystamine in a murine model of Huntington's disease", J Neurosci, 22, pp.8942~8950 (2002)[DOI]
76. Wang X, "Cerebral PET imaging and histological evidence of transglutaminase inhibitor cystamine induced neuroprotection in transgenic R6", 2 mouse model of Huntington's disease, 2005, pp.231, 57~66
77. Case A, "Development of a mechanism-based assay for tissue transglutaminase--results of a high-throughput screen and discovery of inhibitors", Anal Biochem, 338, pp.237~244 (2005)[DOI]

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