경동맥화학색전술을 받은 노인 간세포암 환자의 증상, 미충족 요구 및 재원일수 영향요인

Abstract

Purpose: This descriptive study aimed to identify symptoms, unmet needs, and length of hospital stay in older patients with hepatocellular carcinoma (HCC) who underwent transarterial chemoembolization (TACE), as well as to examine factors influencing prolonged hospitalization. Methods: This research included 102 patients aged 65 years or older who received TACE at two university hospitals in South Korea. Data were collected from December 2023 to September 2024 using structured questionnaires and reviews of medical records. Statistical analysis was performed using SPSS/WIN 24.0, including independent t-tests, one-way ANOVA, Pearson correlation coefficients, and logistic regression analysis. Results: Unmet needs significantly varied according to the severity of postembolization syndrome, particularly nausea (F=4.38, p=.006) and vomiting (F=6.13, p=.003). In addition, nausea (r=0.34, p=.001) and vomiting (r=0.32, p=.001) demonstrated a positive correlation with unmet needs. All components of the syndrome were associated with prolonged hospital stay. Logistic regression analysis identified post-procedural pain (OR=30.51, CI=2.56- 364.11, p=.007) and fever (OR=13.52, CI=2.51-72.79, p=.002) as significant predictors of prolonged hospitalization, defined as a length of stay of three days or more. Conclusion: These findings suggest that establishing proactive management strategies for postembolization syndrome in patients undergoing TACE may help reduce unmet needs, shorten hospital stays, and ultimately contribute to improved treatment outcomes.