Treatment of melasma using a combination of CO2 laser and Q-switched ruby laser
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Background and ObjectivesThe CO2 laser is a tissue-selective laser that removes superficial lesions by vaporization and ablation. The Q-switched ruby laser (QSRL) is a pigment-selective laser that induces the disruption of melanosomes. This study aimed to evaluate the effects of a combination treatment of the CO2 laser and QSRL on melasma.Materials and MethodsFifteen patients with melasma were initially treated with a CO2 laser, followed by multiple QSRL toning. Photographs were taken on the first visit, on completion of the prescribed regimen, and 6 months after the treatment. The melasma area and severity index (MASI) and melasma severity scale (MSS) were evaluated through clinical photographs. Patients subjectively evaluated their improvement on a 5-point scale.ResultsThere was a significant change in both mean MASI and MSS scores after the combination treatment with the CO2 laser and QSRL. The MASI score decreased from 5.82 ± 2.6393 to 2.607 ± 1.6973 (p = 0.001). The MSS score significantly decreased from 2.67 ± 0.488 to 1.20 ± 0.561 (p < 0.001). There were no statistically significant differences in the MASI (p = 0.891) and MSS scores (p = 0.046) between post-procedure and 6-month follow-up.ConclusionThe combination of a CO2 laser and QSRL appears to be effective in the treatment of melasma.
Abstract
Background and ObjectivesThe CO2 laser is a tissue-selective laser that removes superficial lesions by vaporization and ablation. The Q-switched ruby laser (QSRL) is a pigment-selective laser that induces the disruption of melanosomes. This study aimed to evaluate the effects of a combination treatment of the CO2 laser and QSRL on melasma.Materials and MethodsFifteen patients with melasma were initially treated with a CO2 laser, followed by multiple QSRL toning. Photographs were taken on the first visit, on completion of the prescribed regimen, and 6 months after the treatment. The melasma area and severity index (MASI) and melasma severity scale (MSS) were evaluated through clinical photographs. Patients subjectively evaluated their improvement on a 5-point scale.ResultsThere was a significant change in both mean MASI and MSS scores after the combination treatment with the CO2 laser and QSRL. The MASI score decreased from 5.82 ± 2.6393 to 2.607 ± 1.6973 (p = 0.001). The MSS score significantly decreased from 2.67 ± 0.488 to 1.20 ± 0.561 (p < 0.001). There were no statistically significant differences in the MASI (p = 0.891) and MSS scores (p = 0.046) between post-procedure and 6-month follow-up.ConclusionThe combination of a CO2 laser and QSRL appears to be effective in the treatment of melasma.
참고문헌 (17)
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