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Application of photobiomodulation therapy in the recovery of a fracture model in different countries: a concise review

Andrew Padalhin|김경욱
대한의학레이저학회 (Korean Society for Laser Medicine and Surgery)|2022.12|Medical Lasers|제11권 제4호|pp. 201-207|DOI 10.25289/ML.22.055

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키워드

BonePhototherapyBone regeneration
주제분류의학일반

초록

The bone is a dynamic biological tissue composed of metabolically active cells which are integrated into a hard framework. However, it can be injured due to trauma or infections and this can result in bone defects. Hence, bone generation or bone healing has been an interesting field of orthopedics and has been the subject of multiple studies. As a result, various substances which promote osteogenesis and angiogenesis have been identified, but their mechanism of action has not yet been completely elucidated. Owing to its anti-inflammatory and wound-healing effects, photobiomodulation (PBM) has been proposed in the treatment of various disease conditions. Specifically, in orthopedics, multiple studies have been conducted to treat bone generation or bone union using PBM. The clinical improvement of bone healing as well as various substances and mechanisms of osteogenesis and angiogenesis by PBM have been identified although the mechanism of action is not fully understood. This review summarizes the published reports on the bone healing effects of PBM treatment in fracture sites.

Abstract

The bone is a dynamic biological tissue composed of metabolically active cells which are integrated into a hard framework. However, it can be injured due to trauma or infections and this can result in bone defects. Hence, bone generation or bone healing has been an interesting field of orthopedics and has been the subject of multiple studies. As a result, various substances which promote osteogenesis and angiogenesis have been identified, but their mechanism of action has not yet been completely elucidated. Owing to its anti-inflammatory and wound-healing effects, photobiomodulation (PBM) has been proposed in the treatment of various disease conditions. Specifically, in orthopedics, multiple studies have been conducted to treat bone generation or bone union using PBM. The clinical improvement of bone healing as well as various substances and mechanisms of osteogenesis and angiogenesis by PBM have been identified although the mechanism of action is not fully understood. This review summarizes the published reports on the bone healing effects of PBM treatment in fracture sites.

참고문헌 (55)

  1. Bailey FR, "Bailey's textbook of histology", pp.170~205 (1978), Williams & Wilkins
  2. Coe FL, "Disorders of bone and mineral metabolism", pp.175~176 (1992), Raven Press
  3. Sathyendra V, "Basic science of bone healing", Hand Clin, 29, pp.473~481 (2013)
  4. Andrew Reyes Padalhin, "Brief Retrospect on the Use of Photobiomodulation (PBM) Therapy for Augmented Bone Regeneration (ABR)", Medical Lasers, 10(1), pp.15~21 (2021), 대한의학레이저학회[DOI]
  5. Kalfas IH, "Principles of bone healing", Neurosurg Focus, 10, pp.E1~ (2001)
  6. Einhorn TA, "Orthopaedic basic science: foundations of clinical practice", pp.331~346 (2007), Amer Academy of Orthopaedic
  7. Aro HT, "Bone-healing patterns affected by loading, fracture fragment stability, fracture type, and fracture site compression", Clin Orthop Relat Res, (293), pp.8~17 (1993)
  8. Kwong FN, "Recent developments in the biology of fracture repair", J Am Acad Orthop Surg, 16, pp.619~625 (2008)
  9. Einhorn TA, "The science of fracture healing", J Orthop Trauma, 19(10 Suppl), pp.S4~S6 (2005)
  10. Day L, "Electrical stimulation in the treatment of ununited fractures", Clin Orthop Relat Res, (161), pp.54~57 (1981)
  11. Sheikh B, "Treatment and rehabilitation of fractures", pp.1~6 (2000), Lippincott Williams & Wilkins
  12. Castillo RC, "Impact of smoking on fracture healing and risk of complications in limb-threatening open tibia fractures", J Orthop Trauma, 19, pp.151~157 (2005)
  13. McKibbin B, "The biology of fracture healing in long bones", J Bone Joint Surg Br, 60-B, pp.150~162 (1978)
  14. Tsiridis E, "Molecular aspects of fracture healing: which are the important molecules?", Injury, 38(Suppl 1), pp.S11~S25 (2007)
  15. Claes L, "The effect of mechanical stability on local vascularization and tissue differentiation in callus healing", J Orthop Res, 20, pp.1099~1105 (2002)
  16. Glowacki J, "Angiogenesis in fracture repair", Clin Orthop Relat Res, (355 Suppl), pp.S82~S89 (1998)
  17. Department of Orthopedic Surgery, "Textbook of fractures and joint injuries", pp.21~25 (2016), Koonja
  18. Burchardt H, "Transplantation of bone", Surg Clin North Am, 58, pp.403~427 (1978)
  19. Cho TJ, "Differential temporal expression of members of the transforming growth factor beta superfamily during murine fracture healing", J Bone Miner Res, 17, pp.513~520 (2002)
  20. DePalma AF, "Anterior interbody fusion for severe cervical disc degeneration", Surg Gynecol Obstet, 134, pp.755~758 (1972)
  21. Kon T, "Expression of osteoprotegerin, receptor activator of NFkappaB ligand(osteoprotegerin ligand)and related proinflammatory cytokines during fracture healing", J Bone Miner Res, 16, pp.1004~1014 (2001)
  22. Mester E, "The biomedical effects of laser application", Lasers Surg Med, 5, pp.31~39 (1985)
  23. Anders JJ, "Low-level light", laser therapy versus photobiomodulation therapy, 2015, pp.33, 183~184
  24. Hyun Seok Ryu, "Decade Long Survey of Low-level Laser Therapy", Photobiomodulation (LLLT, Medical Lasers, pp.2021, 10(3)[DOI]
  25. Sousa AS, "Photobiomodulation and salivary glands : a systematic review", Lasers Med Sci, 35, pp.777~788 (2020)
  26. Celine DG. Abueva, "Photobiomodulation Therapy in the Treatment of Salivary Dysfunction", Medical Lasers, 11(1), pp.15~20 (2022), 대한의학레이저학회
  27. de Freitas LF, "Proposed mechanisms of photobiomodulation or low-level light therapy", IEEE J Sel Top Quantum Electron, 22, pp.7000417~ (2016)
  28. Ji Won Kang, "Stability and Effectiveness of Laser and Liquiband Treatments in the Rat Model of Oral Ulcer", Medical Lasers, 10(4), pp.207~213 (2021), 대한의학레이저학회[DOI]
  29. Karu TI, "Mitochondrial signaling in mammalian cells activated by red and near-IR radiation", Photochem Photobiol, 84, pp.1091~1099 (2008)
  30. Frozanfar A, "The effects of low level laser therapy on the expression of collagen type I gene and proliferation of human gingival fibroblasts(Hgf3-Pi 53) : in vitro study", Iran J Basic Med Sci, 16, pp.1071~1074 (2013)
  31. Manzano-Moreno FJ, "The effect of low-level diode laser therapy on early differentiation of osteoblast via BMP-2", TGF-β1 and its receptors, 2015, pp.43, 1926~1932
  32. Pyo SJ, "Low-level laser therapy induces the expressions of BMP-2, osteocalcin, and TGF-β1 in hypoxic-cultured human osteoblasts", Lasers Med Sci, 28, pp.543~550 (2013)
  33. Pejcic A, "Anti-inflammatory effect of low level laser treatment on chronic periodontitis", Med Laser Appl, 26, pp.27~34 (2011)
  34. Schlundt C, "Macrophages in bone fracture healing : their essential role in endochondral ossification", Bone, 106, pp.78~89 (2018)
  35. Hamblin MR, "Photobiomodulation or low-level laser therapy", J Biophotonics, 9, pp.1122~1124 (2016)
  36. Hashmi JT, "Role of low-level laser therapy in neurorehabilitation", PM R, 2(12 Suppl 2), pp.S292~S305 (2010)
  37. Chung H, "The nuts and bolts of low-level laser(light)therapy", Ann Biomed Eng, 40, pp.516~533 (2012)
  38. Tim CR, "Effects of low level laser therapy on inflammatory and angiogenic gene expression during the process of bone healing : a microarray analysis", J Photochem Photobiol B, 154, pp.8~15 (2016)
  39. Fernandes KR, "Effects of low-level laser therapy on the expression of osteogenic genes related in the initial stages of bone defects in rats", J Biomed Opt, 18, pp.038002~ (2013)
  40. Batista JD, "Low-level laser therapy on bone repair : is there any effect outside the irradiated field?", Lasers Med Sci, 30, pp.1569~1574 (2015)
  41. Magri AMP, "Photobiomodulation guided healing in a sub-critical bone defect in calvarias of rats", Laser Ther, 28, pp.171~179 (2019)
  42. Tim CR, "Low-level laser therapy enhances the expression of osteogenic factors during bone repair in rats", Lasers Med Sci, 29, pp.147~156 (2014)
  43. Escudero JSB, "Photobiomodulation therapy(PBMT)in bone repair : a systematic review", Injury, 50, pp.1853~1867 (2019)
  44. Tani A, "Red(635 nm), near-infrared(808 nm)and violetblue(405 nm)photobiomodulation potentiality on human osteoblasts and mesenchymal stromal cells : a morphological and molecular in vitro study", Int J Mol Sci, 19, pp.1946~ (2018)
  45. Fallahnezhad S, "Effect of low-level laser therapy and oxytocin on osteoporotic bone marrow-derived mesenchymal stem cells", J Cell Biochem, 119, pp.983~997 (2018)
  46. Fekrazad R, "Photobiomodulation with single and combination laser wavelengths on bone marrow mesenchymal stem cells : proliferation and differentiation to bone or cartilage", Lasers Med Sci, 34, pp.115~126 (2019)
  47. Mostafavinia A, "Effect of in vivo low-level laser therapy on bone marrow-derived mesenchymal stem cells in ovariectomy-induced osteoporosis of rats", J Photochem Photobiol B, 175, pp.29~36 (2017)
  48. Vale KLD, "The effects of photobiomodulation delivered by light-emitting diode on stem cells from human exfoliated deciduous teeth : a study on the relevance to pluripotent stem cell viability and proliferation", Photomed Laser Surg, 35, pp.659~665 (2017)
  49. Yang D, "Effects of light-emitting diode irradiation on the osteogenesis of human umbilical cord mesenchymal stem cells in vitro", Sci Rep, 6, pp.37370~ (2016)
  50. Peat FJ, "In vitro effects of high-intensity laser photobiomodulation on equine bone marrow-derived mesenchymal stem cell viability and cytokine expression", Photomed Laser Surg, 36, pp.83~91 (2018)
  51. Ribeiro LNS, "Low-level laser therapy(LLLT)improves alveolar bone healing in rats", Lasers Med Sci, 37, pp.961~969 (2022)
  52. Cury V, "Low level laser therapy increases angiogenesis in a model of ischemic skin flap in rats mediated by VEGF, HIF-1αand MMP-2", J Photochem Photobiol B, 125, pp.164~170 (2013)
  53. Khadra M, "Enhancement of bone formation in rat calvarial bone defects using low-level laser therapy", Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 97, pp.693~700 (2004)
  54. Luger EJ, "Effect of low-power laser irradiation on the mechanical properties of bone fracture healing in rats", Lasers Surg Med, 22, pp.97~102 (1998)
  55. Nissan J, "Effect of low intensity laser irradiation on surgically created bony defects in rats", J Oral Rehabil, 33, pp.619~924 (2006)

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