Pore and Acne Scar Treatment with a Q-switched Laser Using a Novel Fractional MDF (Multi-depth Focusing) Handpiece: A Pilot Study
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Background and ObjectivesAlthough skin rejuvenation is not within the usual repertoire of the Q-switched 1064 nm Nd:YAG (Q-NDY) laser, the development of a multi-depth focusing (MDF) handpiece allowing user-selectable depths of focus has changed this. The current in-house pilot study was designed to assess the safety and efficacy of a Q-NDY laser fitted with an MDF handpiece in the treatment of enlarged pores and acne scars.Materials and MethodsTen patients with enlarged pores and acne scars were recruited into the study as volunteers. Clinical photographs were taken at baseline and then at six weeks (A1) and three months (A2) after the final treatment, based on which a quintile scale physician global assessment (PGA) was obtained at A2 scored by two independent blinded dermatologists. Patients subjectively scored their satisfaction with the treatment in a questionnaire at A2, also on a quintile scale.ResultsIn general, patients showed a statistically significant improvement in both the pores and acne scars at both A1 and A2, with a trend towards continued improvement between the first and second assessments, more particularly for the acne scars. The average percentage improvements for the pores at A1 and A2 were 48.45 ± 16.1% and 57.8 ± 15.2% (p = 0.001 for both), respectively, for acne scars, the respective values were 27.8 ± 15.0% and 34.2 ± 24.3% (p = 0.0008 for A1, 0.0004 for A2). No difference was seen between the subjects who had three sessions and those who had four, suggesting that the 3-treatment protocol was ideal, although numbers were too small to make any generalization. The average PGA score was 3.3/4 and the average subject satisfaction score was 3.4/4. The average pain score was 3.7 (range 3-5), and no adverse events were reported during both the treatment and follow-up periods.ConclusionFurther controlled studies in larger populations are warranted to confirm the optimistic results of this pilot study.
Abstract
Background and ObjectivesAlthough skin rejuvenation is not within the usual repertoire of the Q-switched 1064 nm Nd:YAG (Q-NDY) laser, the development of a multi-depth focusing (MDF) handpiece allowing user-selectable depths of focus has changed this. The current in-house pilot study was designed to assess the safety and efficacy of a Q-NDY laser fitted with an MDF handpiece in the treatment of enlarged pores and acne scars.Materials and MethodsTen patients with enlarged pores and acne scars were recruited into the study as volunteers. Clinical photographs were taken at baseline and then at six weeks (A1) and three months (A2) after the final treatment, based on which a quintile scale physician global assessment (PGA) was obtained at A2 scored by two independent blinded dermatologists. Patients subjectively scored their satisfaction with the treatment in a questionnaire at A2, also on a quintile scale.ResultsIn general, patients showed a statistically significant improvement in both the pores and acne scars at both A1 and A2, with a trend towards continued improvement between the first and second assessments, more particularly for the acne scars. The average percentage improvements for the pores at A1 and A2 were 48.45 ± 16.1% and 57.8 ± 15.2% (p = 0.001 for both), respectively, for acne scars, the respective values were 27.8 ± 15.0% and 34.2 ± 24.3% (p = 0.0008 for A1, 0.0004 for A2). No difference was seen between the subjects who had three sessions and those who had four, suggesting that the 3-treatment protocol was ideal, although numbers were too small to make any generalization. The average PGA score was 3.3/4 and the average subject satisfaction score was 3.4/4. The average pain score was 3.7 (range 3-5), and no adverse events were reported during both the treatment and follow-up periods.ConclusionFurther controlled studies in larger populations are warranted to confirm the optimistic results of this pilot study.
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