어린이의 하악골에서 발생한 Burkitt 림프종
BURKITT’S LYMPHOMA OF THE MANDIBLE IN A CHILD
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초록
Burkitt 림프종은 B림프구 기원의 악성종양으로 비호지킨 림프종(non-Hodgkin’s lymphoma)의 한 종류이다. Burkitt 림프종은 임상적으로 아프리카에서 나타나는 지역형(endemic), 세계 각지에서 발생하는 산발형(sporadic), 면역결핍상태와관련되어 나타나는 형태로 나눌 수 있다. 과거에는 그 예후가 매우 불량했으나, 최근에는 집중적인 화학요법으로 인한 치료성공률이 50-80%에 달한다. 많은 경우 악골을 포함하고 있으며 임상증상으로는 심하게 흔들리는 치아, 치아의 변위 그리고치은의 발적 및 부종 등이 있다. 본 증례는 진행속도가 상당히 빠른 Burkitt 림프종에 이환된 환아에 대한 내용이다. 악골에 생긴 병소로 내원하였으며, 치과에서 처음 진단하였고 신속하고 적절한 치료를 통해 양호한 결과를 얻었다.
Abstract
Burkitt’s lymphoma is a malignant tumor originated from B lymphocyte and a type of non-hodgkin lymphoma. It is clinically classified by endemic, sporadic and immune deficient forms. In the past, it had poor prognosis but in recent years survival rate is 50~80% treated by intensive chemotherapeutic regimens. Mostly it is a lesion of the jaws. Clinical symptoms are severe tooth mobility, displacement, gingival redness and swelling. This case is about a patient with aggressively progressing Burkitt’s lymphoma of the jaws. Initial diagnosis was done in dental hospital and it has shown satisfactory outcome by prompt and appropriate treatment.
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