보건의료 빅데이터를 이용한 유아기 우식증과 칸디다증의 연관성 분석
Association between Candidiasis and Early Childhood Caries : Analysis Using Healthcare Big Data
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이 연구의 목적은 칸디다증과 유아기 우식증의 연관성을 밝히고, 생후 1년 내의 칸디다증 또는 칸디다 구내염 경험이 유아기 우식증의 위험 인자로 고려될 수 있는지 알아보는 것이었다. 이를 위해 건강 보험 심사 평가원에서 2010년 1월부터 2012년 12월까지 태어난 어린이들의 의료 급여 이용 기록을 제공받았으며, 이 중 치과 진료 기록이 없는 경우는 배제하였다. 연구 대상을 칸디다증 경험 여부, 칸디다 구내염 경험 여부에 따라 나누어 치아 우식유병률을 비교하였다. 또한 생후 1년 이내에 의료 기록을 갖는 어린이들을 만 1세 이전의 칸디다증 경험 여부, 칸디다 구내염 경험 여부에 따라 분류해 각 집단의 만 1세 이후 치아 우식 유병률을 비교하였다. 칸디다증 또는 칸디다 구내염을 진단받았던 어린이 집단의 치아 우식 유병률은 두 질환을 경험하지 않은 어린이 집단과 유의한 차이를 나타냈다. 만 1세 이전에 칸디다증 또는 칸디다 구내염을 진단받았던 어린이 집단에서 만 1세 이후부터 만 6세 이전까지 치아 우식에 이환된 어린이의 비율은 두 질환을 진단받지 않은 어린이 집단과 의미 있는 차이를 보였다.
Abstract
The aim of this study was to identify the association between candidiasis and early childhood caries and to investigate whether the experience of candidiasis or oral candidiasis before age 1 can be considered as a risk factor for early childhood caries. The database used in this study was provided by Health Insurance Review and Assessment Service. Medical records of children born from January 2010 to December 2012 were obtained, and those without dental records were excluded. Subjects were divided into several groups based on the experience of candidiasis or oral candidiasis before age 6: candidiasis group and non-candidiasis group; oral candidiasis group and non-oral candidiasis group. Another categorization was done according to the experience of candidiasis or oral candidiasis before age 1. The incidence rate of early childhood caries in each group were compared. The prevalence of dental caries in children who have been diagnosed with candidiasis or oral candidiasis before age 6 was significantly different from those who have not experienced candidiasis. Similarly, children who have suffered from candidiasis or oral candidiasis before age 1 had significantly different incidence of caries from the children without candidiasis experience.
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