Dental Treatment Patterns in Pediatric Patients with Rare Diseases: A Retrospective Analysis at Yonsei University Dental Hospital
0
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
This study aimed to investigate dental treatment patterns in pediatric patients with rare diseases at Yonsei University Dental Hospital over 3 years. Data of 786 pediatric patients diagnosed with rare diseases who received dental treatment between January 2020 and December 2022 were analyzed retrospectively. Patients were identified through electronic medical record screening for rare disease codes registered with the Korea Disease Control and Prevention Agency. Demographics, rare disease categories, and dental treatment methods and modalities were analyzed using chi-square tests, Fisher’s exact tests, t-tests, and logistic regression. Significant differences in dental treatment needs and methods were observed among categories. Patients with nervous system diseases were less likely to receive preventive or restorative treatments, such as sealants (p = 0.0062) and composite restoration (p = 0.0171), and had a higher prevalence of disabilities (p < 0.00001), leading to greater dental care challenges. Conversely, patients with congenital malformations required more extensive treatments, including stainless-steel crowns (p = 0.0118) and surgery (p = 0.0234), often under general anesthesia (p = 0.0337). The study underscores the importance of tailored dental care protocols and interdisciplinary collaboration to address the needs of pediatric patients with rare diseases, enhancing their oral health outcomes and quality of life.
Abstract
This study aimed to investigate dental treatment patterns in pediatric patients with rare diseases at Yonsei University Dental Hospital over 3 years. Data of 786 pediatric patients diagnosed with rare diseases who received dental treatment between January 2020 and December 2022 were analyzed retrospectively. Patients were identified through electronic medical record screening for rare disease codes registered with the Korea Disease Control and Prevention Agency. Demographics, rare disease categories, and dental treatment methods and modalities were analyzed using chi-square tests, Fisher’s exact tests, t-tests, and logistic regression. Significant differences in dental treatment needs and methods were observed among categories. Patients with nervous system diseases were less likely to receive preventive or restorative treatments, such as sealants (p = 0.0062) and composite restoration (p = 0.0171), and had a higher prevalence of disabilities (p < 0.00001), leading to greater dental care challenges. Conversely, patients with congenital malformations required more extensive treatments, including stainless-steel crowns (p = 0.0118) and surgery (p = 0.0234), often under general anesthesia (p = 0.0337). The study underscores the importance of tailored dental care protocols and interdisciplinary collaboration to address the needs of pediatric patients with rare diseases, enhancing their oral health outcomes and quality of life.
참고문헌 (55)
- 2021Annual Report on the Rare Disease Patients in Korea, "Korea Disease Control and Prevention Agency", Korea Disease Control and Prevention Agency, 2~ (2023)
- 2021Annual Report on the Rare Disease Patients in Korea, "Korea Disease Control and Prevention Agency", Korea Disease Control and Prevention Agency, 62~70 (2023)
- Friedlander AH, "The pathophysiology, medical management and dental implications of fragile X, Rett, and Prader-Willi syndromes", J Calif Dent Assoc, 31, pp.693~702 (2003)
- Stojanović L, "Etiological aspects of anterior open bite", Med Pregl, 60, pp.151~155 (2007)
- Carter P, "Stereotypical hand movements in 144 subjects with Rett syndrome from the population-based Australian database", Mov Disord, 25, pp.282~288 (2010)
- Rizkallah J, "Evaluation of the severity of malocclusions in children affected by osteogenesis imperfecta with the peer assessment rating and discrepancy indexes", Am J Orthod Dentofacial Orthop, 143, pp.336~341 (2013)
- Ribeiro EM, "A clinical multicenter study of orofacial features in 26 brazilian patients with different types of mucopolysaccharidosis", Cleft Palate Craniofac J, 52, pp.352~358 (2015)
- Tosi LL, "Initial report of the osteogenesis imperfecta adult natural history initiative", Orphanet J Rare Dis, 10, pp.146~ (2015)
- Ruy Carneiro NC, "Oral health of children and adolescents with mucopolysaccharidosis and mother’s Sense of Coherence", Spec Care Dentist, 37, pp.223~229 (2017)
- Shaw L, "Correlation of manual dexterity and comprehension with oral hygiene and periodontal status in mentally handicapped adults", Community Dent Oral Epidemiol, 17, pp.187~189 (1989)
- Thornton JB, "Oral hygiene levels and periodontal disease prevalence among residents with mental retardation at various residential settings", Spec Care Dentist, 9, pp.186~190 (1989)
- Traci MA, "Assessing secondary conditions among adults with developmental disabilities : a preliminary study", Ment Retard, 40, pp.119~131 (2002)
- Scarpa M, "Mucopolysaccharidosis type II : European recommendations for the diagnosis and multidisciplinary management of a rare disease", Orphanet J Rare Dis, 6, pp.72~ (2011)
- Wang X, "Genetic and environmental factors associated with dental caries in children : the Iowa Fluoride Study", Caries Res, 46, pp.177~184 (2012)
- Grossmann N, "Nasal airflow and olfactory function after the repair of cleft palate(with and without cleft lip)", Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 100, pp.539~544 (2005)
- Mani M, "Factors related to quality of life and satisfaction with nasal appearance in patients treated for unilateral cleft lip and palate", Cleft Palate Craniofac J, 50, pp.432~439 (2013)
- Sjogreen L, "Oral health and oromotor function in rare diseases-a database study", Swed Dent J, 39, pp.23~37 (2015)
- Debossan SAT, "Access to oral health care services for individuals with rare genetic diseases affecting skeletal development", Spec Care Dentist, 42, pp.32~40 (2022)
- Molina-García A, "Impact of rare diseases in oral health", Med Oral Patol Oral Cir Bucal, 21, pp.E587~E594 (2016)
- Yu JW, "A survey on the current status and the opinion of professional oral health care for oral cancer patients", J Korean Soc Dent Hyg, 19, pp.1025~1036 (2019)
- "Oral cancer: Prevention and patient management"[URL]
- Oliveira AC, "Utilization of oral health care for Down syndrome patients", Rev Saude Publica, 42, pp.693~699 (2008)
- Liu Z, "Impact of oral health behaviors on dental caries in children with intellectual disabilities in Guangzhou, China", Int J Environ Res Public Health, 11, pp.11015~11027 (2014)
- Braúna AP, "Risk factors for dental caries in children with developmental disabilities", Braz Oral Res, 30, pp.S1806-83242016000100266~ (2016)
- Hanisch M, "Association between oral health-related quality of life in people with rare diseases and their satisfaction with dental care in the health system of the Federal Republic of Germany", Int J Environ Res Public Health, 15, pp.1732~ (2018)
- Macedo G, "Access to dental care of special patients : the perception of primary care dentists", Rev Ciênc Plur, 4, pp.67~80 (2018)
- Janas A, "Dental issues in Rett syndrome", Dev Period Med, 19, pp.478~481 (2015)
- "International Statistical Classification of Diseases and Related Health Problems"[URL]
- Cines DB, "Congenital and acquired thrombocytopenia", Hematology Am Soc Hematol Educ Program, 2004, pp.390~406 (2004)
- Martin R, "Recognition and diagnosis of mucopolysaccharidosis II(Hunter syndrome)", Pediatrics, 121, pp.E377~E386 (2008)
- Bálint G, "Hereditary disorders mimicking and", or causing premature osteoarthritis, 2000, pp.14, 219~250
- You SJ, "Factors influencing the evolution of West syndrome to Lennox-Gastaut syndrome", Pediatr Neurol, 41, pp.111~113 (2009)
- Ko BL, "Dental Management of a Pediatric Patient with Moyamoya Syndrome : A Rare Clinical Entity", Pediatr Dent, 40, pp.56~58 (2018)
- Bo H, "Dental Management Considerations in a Pediatric Patient with Moyamoya Disease", J Dent Child(Chic), 84, pp.100~105 (2017)
- Kumar A, "Familial atrioventricular septal defect : possible genetic mechanisms", Br Heart J, 71, pp.79~81 (1994)
- Wang PP, "Williams syndrome, Down syndrome, and cognitive neuroscience", Am J Dis Child, 147, pp.1246~1251 (1993)
- Al-Hathlol W, "Challenges in the Dental Management of Rett Syndrome under General Anesthesia : A Rare Disease", Case Rep Dent, 2022, pp.4038221~ (2022)
- Ribeiro RA, "Oral manifestations in Rett syndrome : a study of 17 cases", Pediatr Dent, 19, pp.349~352 (1997)
- Mahdi SS, "Oral Manifestations of Rett Syndrome-A Systematic Review", Int J Environ Res Public Health, 18, pp.1162~ (2021)
- Raluy-Callado M, "The impact of Hunter syndrome(mucopolysaccharidosis type II)on health-related quality of life", Orphanet J Rare Dis, 8, pp.101~ (2013)
- Cumella S, "Needs for oral care among people with intellectual disability not in contact with Community Dental Services", J Intellect Disabil Res, 44, pp.45~52 (2000)
- Anders PL, "Oral health of patients with intellectual disabilities : a systematic review", Spec Care Dentist, 30, pp.110~117 (2010)
- Jacobsen PL, "Epilepsy and the dental management of the epileptic patient", J Contemp Dent Pract, 9, pp.54~62 (2008)
- Regis RR, "Oral findings and dental treatment in a child with West syndrome", Spec Care Dentist, 29, pp.259~263 (2009)
- Bryan RB, "Management of dental patients with seizure disorders", Dent Clin North Am, 50, pp.607~623 (2006)
- Friedlander AH, "The pathophysiology, medical management, and dental implications of autism", J Calif Dent Assoc, 31, pp.681~691 (2003)
- Friedlander AH, "The pathophysiology, medical management, and dental implications of children and young adults having attention-deficit hyperactivity disorder", J Calif Dent Assoc, 31, pp.669~678 (2003)
- Castro T, "Oral characteristics and medical considerations in the dental treatment of individuals with Williams syndrome", Spec Care Dentist, 39, pp.108~113 (2019)
- Fuertes-Gonzalez MC, "Oral health in a group of patients with Rett syndrome in the regions of Valencia and Murcia(Spain) : a case-control study", Med Oral Patol Oral Cir Bucal, 19, pp.E598~E604 (2014)
- Alpoz AR, "Bruxism in Rett syndrome : a case report", J Clin Pediatr Dent, 23, pp.161~163 (1999)
- Buccino MA, "Rett syndrome-a rare and often misdiagnosed syndrome : case report", Pediatr Dent, 11, pp.151~157 (1989)
- Kilbaugh TJ, "Sedation and analgesia in children with developmental disabilities and neurologic disorders", Int J Pediatr, 2010, pp.189142~ (2010)
- Hanamoto H, "Effect of midazolam in autism spectrum disorder: A retrospective observational analysis", Acta Anaesthesiol Scand, 67, pp.606~612 (2023)
- Friedlander L, "Management of rare diseases of the Head, Neck and Teeth : results of a French population-based prospective 8-year study", Orphanet J Rare Dis, 12, pp.94~ (2017)
- Arriagada-Vargas C, "Rare disorders : diagnosis and therapeutic planning for patients seeking orthodontic treatment", J Clin Med, 11, pp.1527~ (2022)
