성인 여성의 월경력 및 산과적 요인이 골밀도에 미치는 영향
Effects of Menstrual History and Reproductive Factors on Bone Mineral Density Among Women
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Objectives : The present study aimed to reveal the effects of menstrual history and obstetric factors on a decrease in bone mineral density (BMD) among women in an urban area. Methods : A total of 756 women were recruited from a city in the middle of this country from Jan. 1st through Dec. 31st, 2007. They underwent anthropometric examinations and BMD and were given self-administered questionnaires about sociodemographic, pregnancy, childbirth and physiological data. Results : The rate of women with reduced bone mass was 54.5%, and the bone mass had a significantly negative correlation with age, age of menarche, period after last delivery and number of offsprings. On the contrary, it had a significantly positive correlation with height, weight, BMI and age of first delivery. After adjustment for age, level of education, monthly income, weight, height and BMI, the risk ratios of menstrual history and obstetric risk factors for the decrease in bone mass was higher for the later age of menarche, post-menopause rather than pre-menopause, the longer period after last delivery, the younger age at first delivery and the greater number of offsprings. For independent effects of menstrual history and obstetric risk factors on a decrease in lumbar bone mass using the hierarchial multiple regression analysis, the influence increased in following orders; age of menarche, period after last delivery, presence of menopause or not, age of first delivery. Conclusion : The study results showed that menstrual history and obstetric risk factors could have an effect on a decrease in BMD independently of sociodemographic and physical characteristics. Therefore it suggests that desirable bone health strategy should include bone loss prevention programs with specific emphasis on these reproduction- related factors.
Abstract
Objectives : The present study aimed to reveal the effects of menstrual history and obstetric factors on a decrease in bone mineral density (BMD) among women in an urban area. Methods : A total of 756 women were recruited from a city in the middle of this country from Jan. 1st through Dec. 31st, 2007. They underwent anthropometric examinations and BMD and were given self-administered questionnaires about sociodemographic, pregnancy, childbirth and physiological data. Results : The rate of women with reduced bone mass was 54.5%, and the bone mass had a significantly negative correlation with age, age of menarche, period after last delivery and number of offsprings. On the contrary, it had a significantly positive correlation with height, weight, BMI and age of first delivery. After adjustment for age, level of education, monthly income, weight, height and BMI, the risk ratios of menstrual history and obstetric risk factors for the decrease in bone mass was higher for the later age of menarche, post-menopause rather than pre-menopause, the longer period after last delivery, the younger age at first delivery and the greater number of offsprings. For independent effects of menstrual history and obstetric risk factors on a decrease in lumbar bone mass using the hierarchial multiple regression analysis, the influence increased in following orders; age of menarche, period after last delivery, presence of menopause or not, age of first delivery. Conclusion : The study results showed that menstrual history and obstetric risk factors could have an effect on a decrease in BMD independently of sociodemographic and physical characteristics. Therefore it suggests that desirable bone health strategy should include bone loss prevention programs with specific emphasis on these reproduction- related factors.
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