경동맥 초음파 검사의 유용성에 대한 연구
Usefulness of Ultrasonography of Carotid Artery
1
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
본 연구에서는 경동맥 주위에 경동맥 내막-중막 두께(IMT) 증가로 발생하는 동맥경화성 폐색증을 알아보고, 경동맥 초음파 검사를 실시한 202명의 대상으로 다음과 같은 결론을 얻었다. 1. 연구 대상자 202명의 일반적 특징은 남자가 120명(59.4%), 여자가 82명(40.6%)이었으며, 평균 연령은 58세였다. 2. 전체 대상자 중 당뇨(DM) 54명(26.7%), 고지혈증(Hyperlipidemia)은 60명(29.7%), 고혈압(Hypertension) 86명(42.6%), 심전도(EKG) 61명(30.2%)으로 나타났다. 3. IMT는 Left IMT가 Right IMT보다 두께가 증가하였으며, 남성이 여성보다 IMT가 두꺼워졌고, 연령이 증가할수록 IMT가 더 증가하였다. 4. IMT & MRA와의 관계는 MRA을 시행한 115명은 검사하지 않은 87명 보다 IMT 두께와의 상관관계가 있는 것으로 나타났다(p<0.01). 5. IMT가 증가할수록 DM, HTN와의 상관관계가 나타났으며, EKG(심전도) Hyperlipidemia(고지혈증)은 상관관계가 없는 것으로 나타났다. 6. MRA을 시행한 115명의 환자에서 MCA의 협착이 있는 군은 Left, Right IMT가 0.94mm, 0.96mm으로 두께가 증가되어 p<0.01로 상관관계가 있는 것으로 나타났으며, IMT가 두꺼울수록 MRA를 실시한 후 MCA에서 동맥 협착(stenosis)으로 나타났다.
Abstract
This study examined 202 patients who was diagnosed as arteriosclerosis obliterans around carotid artery caused by its increase in IMT and who have been tested by carotid artery sonography. The results are as follows : 1. Out of 202 research subjects, 120(59.4%) were male, 82(40.6%) female, and the average age was 58. 2. Among the subjects, 54(26.7%) were diagnosed as DM, 60(29.7%) with hyperlipidemia, 86(42.6%) with hypertension, 61(30.2%) with EGK. 3. There was more increase in the left IMT than in the right IMT, more increase in male subjects than female subjects, and more increase with age. 4. The relationship between IMT & MRA was that subjects tested by MRA showed greater statistically significant correlation than those not tested by MRA(p<0.01). 5. The increase in IMT was correlated with DM and HTN, but not with EKG and hyperlipidemia. 6. Among subjects tested by MRA, those diagnosed with MCA stenosis showed increase upto 0.94 in the left IMT and 0.96 in the right IMT; there was a significant correlation(p<0.01). Thicker IMT was positively correlated with diagnosis of MCA stenosis after MRA test.
참고문헌 (31)
- Davis PH, "Carotid intima-medial thickness is related to cardiovascular risk factors measured from childhood through age", 104, pp.2815~2819 (2001)
- Tonstad S, "Risk factors related to carotid intima-media thickness and plaque in children with familial hypercholesterolemia and control subjects", 16, pp.984~991 (1996)
- Crouse JR, "Risk factors and segment-specific carotid arterial enlargement in the atherosclerosis risk in communities(ARIC) cohort", pp.69~75 (1996), Stroke
- Burke GL, "Arterial wall thickness is associated with pre valent cardiovascular disease in middle-aged adults", pp.26386~26391 (1995), Stroke
- Pignoli P, "Imtimal plus medial thickness of the arterial wall: a direct measurement with ultrasound imaging", pig(li p), pp.1399~74 1406 (1986)
- Wofford JL, "Relation of extent of extracraninal carotid artery atherosclerosis as measured by B-mode ultrasound to the extent of coronary atherosclerosis", pp.1786~1794 (1991)
- O'Leary DH, "Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults", 340, pp.14~22 (1999)
- Pignoli P, "Intimal plus medial thickness of the arterial wall: a direct measurement with ultrasound imageing", pig(li p), pp.1399~74 1406 (1986)
- 조유리, "한국인의 경동맥 내막-중막 두께 정상치와 죽상 경화증 위험인자와의 상관관계", 64(3), pp.275~283 (2003)
- 고영국, "인슐린 비의존형 당뇨병 환자에서 고해상도 B-mode 초음파로 측정한 경동맥 내중막 두께와 죽상경화증 위험인자들과의 관계", 23, pp.234~242 (1999)
- 신이철, "동맥 탄성도 검사로 동맥경화 위험인자와 관상동맥 질환을 가진 환자의 감별에 도움이 되는가?", Korean Circulation Journal, 34(9), pp.845~855 (2004), 대한심장학회
- Pignoli P, "Intimal plus medial thickness of the arterial wall: a direct measurement with ultrasound imageing", pig(li p), pp.1399~74 1406 (1986)
- Poli A, "Ultrasonographic measurement of the common carotid artery wall thickness in hypercholesterolemic patients A new model for the quantitation and follow-up of preclinical atherosclerosis in living human subject", pig(li p), pp.253~70 261 (1988)
- "Progression of carotid atherosclerosis and its determinants a population- based ultrasonography study", pp.33~81 40 (1990)
- Simon A Gariepy J, "Intima-media thickness a new tool for diagnosis and treatment of cardiovascular risk", 20, pp.159~169 (2002)
- O'Leary DH, "Carotid artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults", 340, pp.14~22 (1999), New Engl J Med
- Hillen T, "Carotid atherosclerosis, vascular risk profile and mortality in a population-based sample of functionally healthy elderly subjects: the Berlin ageing study", 247, pp.679~688 (2000)
- Touboul PJ, "Common carotid artery intima-media thickness and brain infarction. GENIC case-control study", 102, pp.313~318 (2000)
- Chambless LE, "Carotid wall thickness is predictive of incident clinical stroke. The Atherosclerosis Risk in Communities (ARIC) study", 151, pp.478~487 (2000)
- Grobbee DE, "Carotid intima-media thickness as an indicator of generalized atherosclerosis", pp.567~573 (1994)
- Yu Sun, "Carotid atherosclerosis, intima media thickness and risk factors-an analysis of 1781 asymptomatic subjects in Taiwan", 164, pp.89~94 (2002)
- 조유리, "한국인의 경동맥 내중막 두께정상치와 죽상경화증 위험인자와의 상관관계", 64, pp.275~283 (2003)
- O'Leary DH, "Distribution and correlates of sonographically detected carotid artery disease in the Cardiovascular Health Study. The CHS Collaborative Research Group", 23(12), pp.1752~1760 (1992)
- "Risk factors in stroke Astatement for physicians by the subcommittee on risk actors and stroke of stroke council", pp.1105~15 11 (1984)
- Wolf PA, "Probability of stroke A risk profile from the Framingham study", pp.312~8 (1991)
- Donahue RB, "Diabetes and risk of stroke", pp.949~52 (1987)
- Moore WS, "Effect on flow rate and vessel calibre on critical arterial stenosis", pp.1~9 (1979)
- Norris JW, "Vascular risks of asymptomatic carotid stenosis", pp.1485~90 (1991)
- Chamblee LE, "carotid wall thickness is predictive of incident clinical stroke: The Atherosclerosis Risk in Communities(ARIC) study", 151, pp.478~487 (2000)
- Amminbakhsh As, "Carotid intima- media thickness measurements: what defines an abnormality? A systematic review", 22, pp.149~157 (1999)
- Shimada K, "Silent cerebrovascular disease in the elderly. Correlation with ambulatory pressure", pp.692~16 699 (1990)