갑상선암의 고용량 131I 치료 시 입원기간의 최적화방안 연구
A Study on Ways to Optimize the Period of Hospitalization During High-Dose 131I Treatment of the Thyroid Cancer
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본 연구는 고용량 방사성옥소 치료환자의 선량률을 거리와 시간대별로 산출하여 방사성옥소 치료를 위한 입원기간의 최적화와 개선방안을 제한 하고자 하였다. 그 결과 100mCi 고용량 옥소치료환자의 24시간 후에 배꼽에서 1,035μSv/hr, 50cm에서 109 μSv/hr, 100cm에서 33μSv/hr로 감쇠 되었다. 150mCi 고용량 옥소치료환자의 24시간 후에 배꼽에서 637μSv/hr, 50cm에서 100μSv/hr, 100cm에서 40μSv/hr로 감쇠 되었다. 180mCi 고용량 옥소치료환자의 24시간 후에 배꼽에서 1,251μSv/hr, 50cm에서 140μSv/hr, 100cm에서 56μSv/hr로 감쇠 되었다. 퇴원기준을 미국 원자력 규제위원회 고시에 70.4μSv/hr이므로 본 연구 결과보다 빠른 퇴원이 가능하다. 치료 환자들의 계속적인 증가 추세로 볼 때 치료병실의 부족을 해소 할 수 있다.
Abstract
This study attempts to propose ways to optimize and improve the period of hospitalization for the radioiodine treatment by calculating the dose rate of patients treated with high-dose radioiodine by distance and time slot. As a result, 24 hours after the patient was treated with 100 mCi high-dose iodine, the dose rate was attenuated to 1,035μSv/hr at the navel, to 109μSv/hr at 50 cm, and to 33μSv/hr at 100 cm. 24 hours after the patient was treated with 150 mCi high-dose iodine, the dose rate was attenuated to 637μSv/hr at the navel, to 100μSv/hr at 50 cm, and to 40μSv/hr at 100 cm. 24 hours after the patient was treated with 180 mCi high-dose iodine, the dose rate was attenuated to 1,251μSv/hr at the navel, 140μSv/hr at 50 cm, and to 56μSv/hr at 100 cm. In light of the current criterion for discharge recommended by the US Nuclear Regulatory Commission being 70.4μSv/hr, the present study indicates earlier discharge is feasible by applying a new scheme. This suggests that the proposed scheme in this study will help to solve the problem of shortage of treatment beds with the increasing trend of patients with thyroid cancer taken into consideration.
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